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| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 269 |
| Release | : 2011-09-16 |
| Genre | : Science |
| ISBN | : 0123876982 |
This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
| Author | : Rowland H. Davis |
| Publisher | : Oxford University Press |
| Total Pages | : 352 |
| Release | : 2000-08-17 |
| Genre | : Science |
| ISBN | : 9780198028574 |
This book will serve as the definitive reference work on the basic physiology, biochemistry, development, genetics, and molecular biology of Neurospora, together with a description of basic laboratory methods. Among the filamentous fungi, Neurospora is a basic model organism, used initially in the establishment of the one-gene, one-enzyme principle, and it has become a favored research organism in a variety of biological problems since that time. Until now, there has been no standard guide to the organism. The book reviews early research since 1927 and describes the current state of the major research programs now being pursued. Each chapter includes detailed literature references for the scholar and experimentalist. Both researchers in the filamentous fungi and biologists requiring information about Neurospora will find this an invaluable resource because it gathers 75 years of scattered research literature into a coherent account.
| Author | : Ulrich Kück |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 372 |
| Release | : 2013-03-09 |
| Genre | : Science |
| ISBN | : 3662103648 |
Mycology, the study of fungi, originated as a subdiscipline of botany and was a descriptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgeff, Kniep and Lindegren are all associated with this early period of fungal genetics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for bio chemical traits. Such fundamental research, conducted largely with Neurospora crassa, led to the one gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cere visiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.
| Author | : David D. Perkins |
| Publisher | : Academic Press |
| Total Pages | : 337 |
| Release | : 2000-10-11 |
| Genre | : Science |
| ISBN | : 0080545505 |
The fungi have been major players in the molecular revolution that has transformed biology. Because they can be manipulated as microorganisms, yeast and Neurospora provide information that is difficult to acquire with plants and animals, and experimental findings with fungi often throw light on corresponding processes in plants and animals. The filamentous fungus Neurospora crassa has become a valuable model organism because of its favorable features for genetic analysis and because of the vast store of information that has been acquired during 75 years of research. This compendium provides researchers and students with a concise account of current knowledge about the genes and genome of Neurospora, setting the stage for research that will follow completion of the genome sequence. This book, which is fully documented and abundantly illustrated, will be an indispensable tool in any laboratory that uses fungi for research in molecular genetics, classical genetics, developmental genetics, or cell biology. Molecular, genetic, and phenotypic information for over 1000 nuclear genes Genetic maps Linkage group assignments for 1000 loci 2300 references, 68 figures Guide to electronic and other sources of information Summary information on the mitochondrial genome cDNAs identified from different stages of life Classical, cytogenetic, and molecular data, anticipating completion of the genome sequence
| Author | : Rowland H. Davis |
| Publisher | : Oxford University Press |
| Total Pages | : 538 |
| Release | : 2000-08-17 |
| Genre | : Science |
| ISBN | : 0190284072 |
This book will serve as the definitive reference work on the basic physiology, biochemistry, development, genetics, and molecular biology of Neurospora, together with a description of basic laboratory methods. Among the filamentous fungi, Neurospora is a basic model organism, used initially in the establishment of the one-gene, one-enzyme principle, and it has become a favored research organism in a variety of biological problems since that time. Until now, there has been no standard guide to the organism. The book reviews early research since 1927 and describes the current state of the major research programs now being pursued. Each chapter includes detailed literature references for the scholar and experimentalist. Both researchers in the filamentous fungi and biologists requiring information about Neurospora will find this an invaluable resource because it gathers 75 years of scattered research literature into a coherent account.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 983 |
| Release | : 2019-06-04 |
| Genre | : Medical |
| ISBN | : 0128139404 |
Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine. Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine
| Author | : Durgadas Prabhakar Kasbekar |
| Publisher | : Caister Academic Press Limited |
| Total Pages | : 0 |
| Release | : 2013 |
| Genre | : Science |
| ISBN | : 9781908230126 |
Building on over 70 years of genetics research, Neurospora continues to be the leading model for the study of the genomics and molecular biology of filamentous fungi. The ease of culture, amenability to genetic and molecular genetic analysis, and the close correlation between genetic and biochemical traits are some of its advantages. Research with Neurospora has provided insights unachievable from work with simpler systems and difficult to extract from more complicated ones, cementing its position as a leading model system. In recent years the application of modern high throughput analyses had led to a deluge of information on the genomics and molecular biology of Neurospora. This timely book aims to distil the most important findings to provide a snapshot of the current research landscape. In this book, internationally recognised Neurospora experts critically review the most important research and demonstrate the breadth of applications to industrial biology, biofuels, agriculture, and human health. The opening chapter is an introduction to the organism. Following chapters cover topics such as: carotenoid biosynthesis, polysaccharide deconstruction, genome biology, genome recombination, gene regulation, signal transduction, self-recognition, development, circadian rhythms and mutation. The book closes with a fascinating look at the history and future trends for research on Neurospora gene and genome analysis. This volume is essential for everyone working with Neurospora and other filamentous fungi. A recommended book for all biology, agriculture and medical libraries.
| Author | : Walter Theodore Federer |
| Publisher | : |
| Total Pages | : 172 |
| Release | : 1963 |
| Genre | : Neurospora |
| ISBN | : |
| Author | : Cees Bos |
| Publisher | : CRC Press |
| Total Pages | : 457 |
| Release | : 2020-11-25 |
| Genre | : Science |
| ISBN | : 1000105717 |
This is a concise guide to the combined use of classical and molecular methods for the genetic analysis and breeding of fungi. It presents basic concepts and experimental designs, and demonstrates the power of fungal genetics for applied research in biotechnology and phytopathology. Case studies of Saccharomyces cerevisiae, Candida albicans, Aspergillus niger, Neurospora crassa, Podospora anserina, Phytophthora infestans and others are included.
| Author | : Kevin Kavanagh |
| Publisher | : John Wiley & Sons |
| Total Pages | : 315 |
| Release | : 2011-08-04 |
| Genre | : Science |
| ISBN | : 111997769X |
Fungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi. Later chapters move on to include more detailed coverage of topics such as antibiotic and chemical commodities from fungi, new chapters on biotechnological use of fungal enzymes and fungal proteomics, and fungal diseases of humans, antifungal agents for use in human therapy and fungal pathogens of plants.
