Neurochemical Aspects Of Alzheimers Disease
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| Author | : Akhlaq A. Farooqui |
| Publisher | : Academic Press |
| Total Pages | : 416 |
| Release | : 2017-05-25 |
| Genre | : Psychology |
| ISBN | : 0128099380 |
Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders. Provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies for Alzheimer's disease Written for researchers, clinicians, and advanced graduate students in neurology, neuroscience, neurochemistry, and neuropharmacology Acts as the first book to provide a comprehensive description of the signal transduction processes associated with pathogenesis of Alzheimer's disease
| Author | : Hanna Falk Erhag |
| Publisher | : Springer Nature |
| Total Pages | : 254 |
| Release | : 2022-01-10 |
| Genre | : Social Science |
| ISBN | : 3030780635 |
This open access book provides insight on how to interpret capability in ageing – one’s individual ability to perform actions in order to reach goals one has reason to value – from a multidisciplinary approach. With for the first time in history there being more people in the world aged 60 years and over than there are children below the age of 5, the book describes this demographic trends as well as the large global challenges and important societal implications this will have such as a worldwide increase in the number of persons affected with dementia, and in the ratio of retired persons to those still in the labor market. Through contributions from many different research areas, it discussed how capability depends on interactions between the individual (e.g. health, genetics, personality, intellectual capacity), environment (e.g. family, friends, home, work place), and society (e.g. political decisions, ageism, historical period). The final chapter summarizes the differences and similarities in these contributions. As such this book provides an interesting read for students, teachers and researchers at different levels and from different fields interested in capability and multidisciplinary research.
| Author | : Joseph T. Coyle |
| Publisher | : |
| Total Pages | : 344 |
| Release | : 1987 |
| Genre | : Medical |
| ISBN | : |
| Author | : Robert Katzman |
| Publisher | : |
| Total Pages | : 524 |
| Release | : 1983 |
| Genre | : Medical |
| ISBN | : |
| Author | : David Dawbarn |
| Publisher | : |
| Total Pages | : 495 |
| Release | : 2007 |
| Genre | : Medical |
| ISBN | : 0198566611 |
Alzheimer's disease is the most common form of dementia in the elderly; 450,000 people in the UK and 4.5 million people in the USA suffer with this disease. This 3rd edition of Neurobiology of Alzheimer's Disease gives a comprehensive and readable introduction to the disease, from molecular pathology to clinical practice. The book is intended for readers new to the field, and it also covers an extensive range of themes for those with in-depth knowledge of Alzheimer's disease. It will therefore act either as an introduction to the whole field of neurodegeneration or it will help experienced researchers to access the latest research in specialist topics. Each chapter is written by eminent scientists leading their fields in neuropathology, clinical practice and molecular neurobiology; appendices detail disease-associate proteins, their sequences, familial mutations and known structures. It will be essential reading for students interested in neurodegeneration and for researchers and clinicians, giving a coherent and cohesive approach to the whole area of research, and allowing access at different levels. For those in the pharmaceutical industry it describes the underlying molecular mechanisms involved in the pathogenesis of Alzheimer's disease and explains how current and potential therapeutics may work.
| Author | : Shelley Jane Allen |
| Publisher | : |
| Total Pages | : 638 |
| Release | : 1985 |
| Genre | : |
| ISBN | : |
| Author | : C.G. Gottfries |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 111 |
| Release | : 2013-03-13 |
| Genre | : Medical |
| ISBN | : 3709133459 |
Neurotransmitter changes taking place in the brain of patients with dementia disorders, mainly Alzheimer type dementia, are reported. Their role in the pathogenesis of Alzheimer's disease is discussed; and the neurochemical changes are considered as a base for formulating treatment strategies. By studying markers in the cerebrospinal fluid, diagnostic methods may be achieved that will aid in diagnosing subgroups of dememtia.
| Author | : Francois Boller |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 183 |
| Release | : 2013-03-08 |
| Genre | : Medical |
| ISBN | : 3642466907 |
This volume presents the proceedings of the symposium held in Toulouse on April 24, 1989, on the topic "Biological Markers of Alzheimer's Disease. " This sym posium was the fourth of a continuing and successful series of Colloques Medecine et Recherche organized by the Fondation IPSEN pour la Recherche Therapeutique, addressing various aspects of contemporary research in the field of Alzheimer's disease (AD). The series started in September 1987 with "Im munology and Alzheimer's Disease," followed 6 months later in Paris by "Gene tics and Alzheimer's Disease" and in September 1988 in Montpellier by "Neuronal Grafting and Alzheimer's Disease. " The present symposium was organized for the purpose of gathering the most current ideas concerning biological markers of AD. The papers presented at this symposium may be roughly subdivided into three groups. The first deals with the markers of AD at the level of the brain itself. These markers are studied either through the cerebrospinal fluid or through techniques such as nuclear magnetic resonance (NMR) - approaches which respectively aim at demonstrating the cerebral changes indicated by the debris resulting from the disease, or studying the possible neurochemical abnormalities that occur in the earlier stages of AD.
| Author | : Abel Lajtha |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 332 |
| Release | : 2008-06-06 |
| Genre | : Medical |
| ISBN | : 0387326707 |
The nervous system is highly fragile, especially during aging, illness and trauma. This book addresses a small sampling of major constituents of neural function at the cellular and molecular level that play crucial roles in development and aging.
| Author | : Piotr Lewczuk |
| Publisher | : |
| Total Pages | : 81 |
| Release | : 2003 |
| Genre | : |
| ISBN | : |
