Neurobiology Diagnosis And Treatment In Autism
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| Author | : Daria Riva |
| Publisher | : John Libbey Eurotext |
| Total Pages | : 242 |
| Release | : 2013-05-01 |
| Genre | : Medical |
| ISBN | : 2742008365 |
Autism is an extremely complex neurodevelopmental disorder that is expressed in a spectrum of phenotypes and is characterised by impaired reciprocal social communication and stereotyped patterns of interests and activities. Its aetiopathogenesis remains poorly understood. This exhaustive synthesis discusses various aspects: A focus on the neurobiology of autism: the candidate genes implicate an involvement of numerous brain regions and a concomitant malfunctioning of neurotransmitter, immunologic, and other mechanisms; The most incisive rehabilitation models in their original formulation and the results achieved with the same or similar protocols in Italian centres (understanding, language therapy, social skill training; The psychopharmacologic options for the condition of autism per se and for its associated, very frequent, comorbidities. It suggests a potential influence on professional practice and enables an up-to-date approach to effective diagnosis and treatment.
| Author | : Joseph D. Buxbaum |
| Publisher | : Academic Press |
| Total Pages | : 494 |
| Release | : 2012-10-25 |
| Genre | : Medical |
| ISBN | : 012391924X |
Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available
| Author | : Steven O. Moldin |
| Publisher | : CRC Press |
| Total Pages | : 559 |
| Release | : 2006-04-25 |
| Genre | : Medical |
| ISBN | : 1420004204 |
Taking an all-inclusive look at the subject, Understanding Autism: From Basic Neuroscience to Treatment reviews state-of-the-art research on the diagnosis, treatment, and prevention of autism. The book addresses potential mechanisms that may underlie the development of autism and the neural systems that are likely to be affected by these molecular,
| Author | : Andreas M. Grabrucker |
| Publisher | : |
| Total Pages | : 117 |
| Release | : 2021 |
| Genre | : |
| ISBN | : |
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
| Author | : Randi Jenssen Hagerman |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 401 |
| Release | : 2014 |
| Genre | : Medical |
| ISBN | : 019993780X |
This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have lead to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.
| Author | : Fred R. Volkmar |
| Publisher | : John Wiley & Sons |
| Total Pages | : 788 |
| Release | : 2005-04-29 |
| Genre | : Psychology |
| ISBN | : 0471721107 |
Now expanded to two volumes, this invaluable reference work provides a comprehensive review of all information presently available about these disorders, drawing on findings and clinical experience from a number of related disciplines such as psychiatry, psychology, neurobiology, pediatrics, etc. The Handbook covers descriptive and diagnostic characteristics, biological contributions, intervention techniques, legal and social issues. The Third Edition is updated to include the newest work in animal models, genetics, neuropsychological processes, screening and assessment methods.
| Author | : Katarzyna Chawarska |
| Publisher | : Guilford Press |
| Total Pages | : 369 |
| Release | : 2010-05-19 |
| Genre | : Psychology |
| ISBN | : 1606239708 |
A review of the current science of identifying and treating autism spectrum disorders in young children examines research issues, approaches to assessment, and developmental, behavioral, and medical intervention models.
| Author | : Gary B. Mesibov |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 136 |
| Release | : 2005-12-29 |
| Genre | : Psychology |
| ISBN | : 0306476797 |
This volume, the first in the series, explores the high-functioning group of people within the spectrum of autism disorders. It is the culmination of over a decade of clinical work and research, including the most current information available about this group. Written in a style that is accessible to both seasoned clinicians and concerned lay persons, this volume is a unique resource.
| Author | : Tatyana B Glezerman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 315 |
| Release | : 2012-08-27 |
| Genre | : Medical |
| ISBN | : 1461441129 |
For years, the typical presentation of autism—the developmental delays, the social and linguistic deficits—has been well known. Despite great variation among children with this condition, certain symptoms are considered hallmarks of the disorder. Less understood is why these symptoms come together to construct autism. And as autism rates continue to rise, this information is ever more vital to accurate diagnosis and treatment. Autism and the Brain offers answers by showing a new neuropsychology of the autistic spectrum, reviewing general brain organization, and relating specific regions and structures to specific clinical symptoms. The author identifies deficiencies in areas of the left-hemisphere associated with the self and identity as central to autism. From this primary damage, the brain further reorganizes to compensate, explaining the diverse behaviors among low- and high-functioning individuals as well as autistic savants. The result is a unique three-dimensional view of brain structure, function, and pathology, with in-depth focus on how the autistic brain: Perceives the world. Understands and uses words. Perceives faces. Understands spatial relations and numbers. Understands feelings and registers emotions. Perceives the self as separate from others. Acts in the world. Challenging readers to re-think their assumptions, Autism and the Brain is breakthrough reading for researchers, clinicians, and graduate students in fields as varied as child and adolescent psychiatry; clinical child, school, and developmental psychology; neuroscience/neurobiology; special education and educational psychology; social work; communication disorders; and public health and policy.
| Author | : Dennis S. Charney |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 1259 |
| Release | : 2013-07-04 |
| Genre | : Medical |
| ISBN | : 0199934959 |
Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.
