Multiscale Modeling Of Brain Mechanics
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| Author | : Mark F. Horstemeyer |
| Publisher | : Elsevier |
| Total Pages | : 276 |
| Release | : 2021-11-02 |
| Genre | : Technology & Engineering |
| ISBN | : 0128181443 |
Multiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection. The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. Presents concepts in a theoretical and thermodynamic framework for each length scale Teaches readers not only how to use an existing multiscale model for each brain but also how to develop a new multiscale model Takes an integrated experimental-computational approach and gives structured multiscale coverage of the problems
| Author | : Mark F. Horstemeyer |
| Publisher | : Academic Press |
| Total Pages | : 278 |
| Release | : 2021-10-27 |
| Genre | : Technology & Engineering |
| ISBN | : 0128181451 |
Multiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection.The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. - Presents concepts in a theoretical and thermodynamic framework for each length scale - Teaches readers not only how to use an existing multiscale model for each brain but also how to develop a new multiscale model - Takes an integrated experimental-computational approach and gives structured multiscale coverage of the problems
| Author | : Dimitrios I. Fotiadis |
| Publisher | : John Wiley & Sons |
| Total Pages | : 404 |
| Release | : 2023-06-07 |
| Genre | : Science |
| ISBN | : 1119517346 |
Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.
| Author | : Jerzy Leszczynski |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 468 |
| Release | : 2009-10-03 |
| Genre | : Science |
| ISBN | : 9048126878 |
"Practical Aspects of Computational Chemistry" presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds, carbon nanotubes and hydrogen storage, adsorption and decomposition of organophosphorus compounds, X-ray crystallography, proton transfer, structure-activity relationships, a description of the REACH programs of the European Union for chemical regulatory purposes, reactions of nucleic acid bases with endogenous and exogenous reactive oxygen species and different aspects of nucleic acid bases, base pairs and base tetrads.
| Author | : Thomas S. Deisboeck |
| Publisher | : CRC Press |
| Total Pages | : 492 |
| Release | : 2010-12-08 |
| Genre | : Mathematics |
| ISBN | : 1439814422 |
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
| Author | : Vittorio Cristini |
| Publisher | : Cambridge University Press |
| Total Pages | : 299 |
| Release | : 2010-09-09 |
| Genre | : Technology & Engineering |
| ISBN | : 1139491504 |
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.
| Author | : Sergey N. Makarov |
| Publisher | : Springer Nature |
| Total Pages | : 395 |
| Release | : 2021 |
| Genre | : Biomedical engineering |
| ISBN | : 3030456234 |
The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.
| Author | : Young Kwon |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 634 |
| Release | : 2007-12-04 |
| Genre | : Technology & Engineering |
| ISBN | : 0387363181 |
This book presents the state-of-the-art in multiscale modeling and simulation techniques for composite materials and structures. It focuses on the structural and functional properties of engineering composites and the sustainable high performance of components and structures. The multiscale techniques can be also applied to nanocomposites which are important application areas in nanotechnology. There are few books available on this topic.
| Author | : Soheil Mohammadi |
| Publisher | : John Wiley & Sons |
| Total Pages | : 564 |
| Release | : 2023-06-09 |
| Genre | : Technology & Engineering |
| ISBN | : 1119033721 |
MULTISCALE BIOMECHANICS Model biomechanical problems at multiple scales with this cutting-edge technology Multiscale modelling is the set of techniques used to solve physical problems which exist at multiple scales either in space or time. It has been shown to have significant applications in biomechanics, the study of biological systems and their structures, which exist at scales from the macroscopic to the microscopic and beyond, and which produce a myriad of overlapping problems. The next generation of biomechanical researchers therefore has need of the latest multiscale modelling techniques. Multiscale Biomechanics offers a comprehensive introduction to these techniques and their biomechanical applications. It includes both the theory of multiscale biomechanical modelling and its practice, incorporating some of the latest research and surveying a wide range of multiscale methods. The result is a thorough yet accessible resource for researchers looking to gain an edge in their biomechanical modelling. Multiscale Biomechanics readers will find: Practical biomechanical applications for a variety of multiscale methods Detailed discussion of soft and hard tissues, and more An introduction to analysis of advanced topics ranging from stenting, drug delivery systems, and artificial intelligence in biomechanics Multiscale Biomechanics is a useful reference for researchers and scientists in any of the life sciences with an interest in biomechanics, as well as for graduate students in mechanical, biomechanical, biomedical, civil, material, and aerospace engineering.
| Author | : Michal Pavelka |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 294 |
| Release | : 2018-08-06 |
| Genre | : Science |
| ISBN | : 3110350955 |
One common feature of new emerging technologies is the fusion of the very small (nano) scale and the large scale engineering. The classical environment provided by single scale theories, as for instance by the classical hydrodynamics, is not anymore satisfactory. The main challenge is to keep the important details while still be able to keep the overall picture and simplicity. It is the thermodynamics that addresses this challenge. Our main reason for writing this book is to explain such general viewpoint of thermodynamics and to illustrate it on a very wide range of examples. Contents Levels of description Hamiltonian mechanics Irreversible evolution Reversible and irreversible evolution Multicomponent systems Contact geometry Appendix: Mathematical aspects
