Multiple Autisms
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| Author | : Jennifer S. Singh |
| Publisher | : U of Minnesota Press |
| Total Pages | : 323 |
| Release | : 2015-12-01 |
| Genre | : Social Science |
| ISBN | : 1452949824 |
Is there a gene for autism? Despite a billion-dollar, twenty-year effort to find out—and the more elusive the answer, the greater the search seems to become—no single autism gene has been identified. In Multiple Autisms, Jennifer S. Singh sets out to discover how autism emerged as a genetic disorder and how this affects those who study autism and those who live with it. This is the first sustained analysis of the practices, politics, and meaning of autism genetics from a scientific, cultural, and social perspective. In 2004, when Singh began her research, the prevalence of autism was reported as 1 in 150 children. Ten years later, the number had jumped to 1 in 100, with the disorder five times more common in boys than in girls. Meanwhile the diagnosis changed to “autistic spectrum disorders,” and investigations began to focus more on genomics than genetics, less on single genes than on hundreds of interacting genes. Multiple Autisms charts this shift and its consequences through nine years of ethnographic observations, analysis of scientific and related literatures, and morethan seventy interviews with autism scientists, parents of children with autism, and people on the autism spectrum. The book maps out the social history of parental activism in autism genetics, the scientific optimism about finding a gene for autism and the subsequent failure, and the cost in personal and social terms of viewing and translating autism through a genomic lens. How is genetic information useful to people living with autism? By considering this question alongside the scientific and social issues that autism research raises, Singh’s work shows us the true reach and implications of a genomic gaze.
| Author | : Anna Stenning |
| Publisher | : Taylor & Francis |
| Total Pages | : 196 |
| Release | : 2024-03-05 |
| Genre | : Biography & Autobiography |
| ISBN | : 1003854184 |
Autism is a profoundly contested idea. The focus of this book is not what autism is or what autistic people are, but rather, it grapples with the central question: what does it take for autistic people to participate in a shared world as equals with other people? Drawing from her close reading of a range of texts, by autistic authors, filmmakers, bloggers, and academics, Anna Stenning highlights the creativity and imagination in these accounts and also considers the possibilities that emerge when the unexpected and novel aspects of experience are attended to and afforded their due space. Approaching these narrative accounts in the context of both the Anthropocene and neoliberalism Stenning unpacks and reframes understandings about autism and identity, agency and mattering, across sections exploring autistic intelligibility, autistic sensibility, and community-oriented collaboration and care. By moving away from the non-autistic stories about autism that have, over time, dominated public conception of the autistic experience and relationships, as well as the cognitive and psychoanalytic paradigms that have reduced autism and autistic people to a homogeneous group, the book instead reveals the multiplicity of autistic subjectivities and their subsequent understandings of oppression. It calls on readers to listen to what autistic people have to say about the possibilities of resistance and solidarity against intersecting currents and eddies of power, which endanger all who challenge the neoliberal conception of Life. A stirring and meaningful departure from atomized accounts of neurological difference, Narrating the Many Autisms ponders big questions about its topic and finds clarity and meaning in the sense-making practices of autistic individuals and groups. It will appeal to scholarly readers across the fields of disability studies, cultural studies, critical psychology, sociology, anthropology, and literature. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.
| Author | : Andreas M. Grabrucker |
| Publisher | : |
| Total Pages | : 117 |
| Release | : 2021 |
| Genre | : |
| ISBN | : |
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
| Author | : Paolo Sassone-Corsi |
| Publisher | : Springer |
| Total Pages | : 141 |
| Release | : 2016-04-04 |
| Genre | : Medical |
| ISBN | : 3319270699 |
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 397 |
| Release | : 2015-10-28 |
| Genre | : Medical |
| ISBN | : 0309376882 |
Children living in poverty are more likely to have mental health problems, and their conditions are more likely to be severe. Of the approximately 1.3 million children who were recipients of Supplemental Security Income (SSI) disability benefits in 2013, about 50% were disabled primarily due to a mental disorder. An increase in the number of children who are recipients of SSI benefits due to mental disorders has been observed through several decades of the program beginning in 1985 and continuing through 2010. Nevertheless, less than 1% of children in the United States are recipients of SSI disability benefits for a mental disorder. At the request of the Social Security Administration, Mental Disorders and Disability Among Low-Income Children compares national trends in the number of children with mental disorders with the trends in the number of children receiving benefits from the SSI program, and describes the possible factors that may contribute to any differences between the two groups. This report provides an overview of the current status of the diagnosis and treatment of mental disorders, and the levels of impairment in the U.S. population under age 18. The report focuses on 6 mental disorders, chosen due to their prevalence and the severity of disability attributed to those disorders within the SSI disability program: attention-deficit/hyperactivity disorder, oppositional defiant disorder/conduct disorder, autism spectrum disorder, intellectual disability, learning disabilities, and mood disorders. While this report is not a comprehensive discussion of these disorders, Mental Disorders and Disability Among Low-Income Children provides the best currently available information regarding demographics, diagnosis, treatment, and expectations for the disorder time course - both the natural course and under treatment.
| Author | : Craig M. Powell |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 421 |
| Release | : 2013 |
| Genre | : Family & Relationships |
| ISBN | : 0199744319 |
The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the human disease. These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated into novel, rational therapies. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments.
| Author | : American Psychiatric Association |
| Publisher | : American Psychiatric Publishing |
| Total Pages | : |
| Release | : 2021-09-24 |
| Genre | : |
| ISBN | : 9781955245180 |
| Author | : Chloe Silverman |
| Publisher | : Princeton University Press |
| Total Pages | : 352 |
| Release | : 2013-09-23 |
| Genre | : Family & Relationships |
| ISBN | : 0691159688 |
How the love and labor of parents have changed our understanding of autism Autism has attracted a great deal of attention in recent years, thanks to dramatically increasing rates of diagnosis, extensive organizational mobilization, journalistic coverage, biomedical research, and clinical innovation. Understanding Autism, a social history of the expanding diagnostic category of this contested illness, takes a close look at the role of emotion—specifically, of parental love—in the intense and passionate work of biomedical communities investigating autism. Chloe Silverman tracks developments in autism theory and practice over the past half-century and shows how an understanding of autism has been constituted and stabilized through vital efforts of schools, gene banks, professional associations, government committees, parent networks, and treatment conferences. She examines the love and labor of parents, who play a role in developing—in conjunction with medical experts—new forms of treatment and therapy for their children. While biomedical knowledge is dispersed through an emotionally neutral, technical language that separates experts from laypeople, parental advocacy and activism call these distinctions into question. Silverman reveals how parental care has been a constant driver in the volatile field of autism research and treatment, and has served as an inspiration for scientific change. Recognizing the importance of parental knowledge and observations in treating autism, this book reveals that effective responses to the disorder demonstrate the mutual interdependence of love and science.
| Author | : Lynn Waterhouse |
| Publisher | : Academic Press |
| Total Pages | : 482 |
| Release | : 2012-12-17 |
| Genre | : Psychology |
| ISBN | : 0123914132 |
The media, scientific researchers, and the Diagnostic and Statistical Manual all refer to "autism" as if it were a single disorder or a single disorder over a spectrum. However, autism is unlike any single disorder in a variety of ways. No single brain deficit is found to cause it, no single drug is found to affect it, and no single cause or cure has been found despite tremendous research efforts to find same. Rethinking Autism reviews the scientific research on causes, symptomology, course, and treatment done to date...and draws the potentially shocking conclusion that "autism" does not exist as a single disorder. The conglomeration of symptoms exists, but like fever, those symptoms aren't a disease in themselves, but rather a result of some other cause(s). Only by ceasing to think of autism as a single disorder can we ever advance research to more accurately parse why these symptoms occur and what the different and varied causes may be. - Autism is a massive worldwide problem with increasing prevalence rates, now thought to be as high as 1 in 38 children (Korea) and 1 in 100 children (CDC- US) - Autism is the 3rd most common developmental disability; 400,000 people in the United States alone have autism - Autism affects the entire brain, including communication, social behavior, and reasoning and is lifelong - There is no known cause and no cure - Funding for autism research quadrupled from 1995 to 2000 up to $45 million, and the Interagency Autism Coordinating Committee has recommended $1 billion funding from 2010-2015
| Author | : Catherine Tan |
| Publisher | : Columbia University Press |
| Total Pages | : 289 |
| Release | : 2024-01-23 |
| Genre | : Social Science |
| ISBN | : 0231556330 |
Winner 2024 Sociology of Disability in Society Outstanding Publication Award, Disability in Society Section, American Sociological Association Movements that take issue with conventional understandings of autism spectrum disorder, a developmental disability, have become increasingly visible. Drawing on more than three years of ethnographic fieldwork and interviews with participants, Catherine Tan investigates two autism-focused movements, shedding new light on how members contest expert authority. Examining their separate struggles to gain legitimacy and represent autistic people, she develops a new account of the importance of social movements as spaces for constructing knowledge that aims to challenge dominant frameworks. Spaces on the Spectrum examines the autistic rights and alternative biomedical movements, which reimagine autism in different and conflicting ways: as a difference to be accepted or as a sickness to treat. Both, however, provide a window into how ideas that conflict with dominant beliefs develop, take hold, and persist. The autistic rights movement is composed primarily of autistic adults who contend that autism is a natural human variation, not a disorder, and advocate for social and cultural inclusion and policy changes. The alternative biomedical movement, in contrast, is dominated by parents and practitioners who believe in the disproven idea that vaccines trigger autism and seek to reverse it with scientifically unsupported treatments. Both movements position themselves in opposition to researchers, professionals, and parents outside their communities. Spaces on the Spectrum offers timely insights into the roles of shared identity and communal networks in movements that question scientific and medical authority.
