Molecular Basis Of Hepatic Metaplasia Of The Pancreas
Download Molecular Basis Of Hepatic Metaplasia Of The Pancreas full books in PDF, epub, and Kindle. Read online free Molecular Basis Of Hepatic Metaplasia Of The Pancreas ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
| Author | : Anthony Atala |
| Publisher | : Academic Press |
| Total Pages | : 1076 |
| Release | : 2012-12-31 |
| Genre | : Technology & Engineering |
| ISBN | : 0123859433 |
New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world's experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system. - Provides comprehensive coverage on this highly topical subject - Contains contributions by the foremost authorities and premiere names in the field of stem cell research - Companion website - http://booksite.elsevier.com/9780123859426/ - contains over 250 color figures in presentation format
| Author | : Joel F. Habener |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 413 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461516692 |
Diabetes mellitus is rapidly increasing in prevalence throughout both developed and developing countries. The social and economic burden of this disease is estimated to cost 14 billion dollars worldwide. In the USA alone, 15 million individuals are diabetic, nearly half of them unaware of their condition. Complications of diabetes mellitus are the leading causes for blindness, limb amputation and chronic renal failure and kidney transplantation in industrialized countries. Further, diabetes mellitus per se and the metabolic derangement associated with diabetes are important risk factors for cardiovascular disease. Diabetes, as defined by an elevated fasting blood glucose level is presently subdivided in etiologically distinct groups. The most prevalent being type 2 (adult onset) diabetes characterized by insulin resistance and failure of the ~-cell to supply insulin in amounts sufficient to meet the body's needs. Type 1 (juvenile) diabetes, most commonly with an onset during childhood and adolescence, is caused by an auto-immune destruction of the pancreatic ~-cells. The causations of both type 1 and type 2 diabetes involve a combination of complex genetic traits and environmental influences. A third category are the mature onset diabetes of the young (MODY). This comparatively small group of patients (-10% of diabetes) presents relative early in life «30 years of age) compared to the more common late onset type 2 diabetes.
| Author | : T. S. Okada |
| Publisher | : |
| Total Pages | : 248 |
| Release | : 1991 |
| Genre | : Science |
| ISBN | : |
The term `transdifferentiation' is used to describe `metamorphosis' of one fully developed cell type into another. There has been much scepticism about the validity of this concept. This book examines the experimental evidence and aims to settle the dispute.
| Author | : United States. Public Health Service. Office of the Surgeon General |
| Publisher | : |
| Total Pages | : 728 |
| Release | : 2010 |
| Genre | : Government publications |
| ISBN | : |
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
| Author | : Stephen Pandol |
| Publisher | : Morgan & Claypool Publishers |
| Total Pages | : 66 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 1615041389 |
The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.
| Author | : Robert Lanza |
| Publisher | : Academic Press |
| Total Pages | : 681 |
| Release | : 2009-06-05 |
| Genre | : Science |
| ISBN | : 0080884970 |
First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. - Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries - Contributions by Nobel Laureates and leading international investigators - Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough - Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate - Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references
| Author | : F. T. Bosman |
| Publisher | : International Agency for Research on Cancer |
| Total Pages | : 424 |
| Release | : 2010-10-15 |
| Genre | : Medical |
| ISBN | : |
"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].
| Author | : Douglas B. Evans |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 413 |
| Release | : 2002 |
| Genre | : Medical |
| ISBN | : 0387951857 |
The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
| Author | : Anthony Atala |
| Publisher | : Gulf Professional Publishing |
| Total Pages | : 580 |
| Release | : 2001-10-12 |
| Genre | : Science |
| ISBN | : 0124366368 |
This reference book combines the tools, experimental protocols, detailed descriptions and know-how for the successful engineering of tissues and organs in one volume.
| Author | : Pablo Muriel |
| Publisher | : Academic Press |
| Total Pages | : 917 |
| Release | : 2017-03-02 |
| Genre | : Science |
| ISBN | : 0128043210 |
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. - Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. - Provides in vivo and in vitro models to study human liver pathology. - Explains the beneficial effects of antioxidants on liver diseases. - Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
