Microbiome Metabolome Brain Vagus Nerve Circuit In Disease And Recovery
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| Author | : Elena L. Paley |
| Publisher | : Elsevier |
| Total Pages | : 536 |
| Release | : 2023-01-25 |
| Genre | : Medical |
| ISBN | : 0443151989 |
Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold's reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book. - Addresses the emerging hypothesis of a dysfunctional microbiome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions - Covers dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea - Presents the conceptual model of food and gut microbial tryptamine vagus nerve circuit - Covers human health and intellectual abilities in the context of both the human genome and the human microbiome
| Author | : Elena L. Paley |
| Publisher | : Elsevier |
| Total Pages | : 320 |
| Release | : 2024-05-31 |
| Genre | : Science |
| ISBN | : 0443288313 |
Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis: A Conceptual Evolution of the Role of Microbiota Tryptamine in Human Diseases provides a detailed investigation into tryptamine, its underlying mechanisms, and metabolism across multiple diseases. The book explores key concepts of tryptamine, its biosynthetic pathways, and its influence in disease, specifically focusing on the Alzheimer's disease-associated gut bacterial sequence (ADAS). Various neurodegenerative conditions are covered alongside cancer, diabetes, infections, and chromosomal aberrations. Additionally, a chapter on gut tryptamine in domestic and agricultural animals is included. The book closes with case studies involving FDG-PET imaging in the context of tryptamine-treated mouse models and Alzheimer's disease patients.This book elucidates the implications of the gut microbiota-mediated tryptamine metabolism for human health, sharing insights into disease etiology, mechanisms, testing, prevention, and treatment. It is an ideal reference for researchers across the biomedical sciences. - Provides a detailed investigation into tryptamine and its role in human health - Explores the relationship between microbiome tryptamine metabolome and a range of diseases, including diabetes, cancer, Alzheimer's disease and Parkinson's disease - Considers the role of tryptamine in cell death and the impairment of genome activities - Paves the way for advances in disease prevention and treatment pathways
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 440 |
| Release | : 2020-10-23 |
| Genre | : Science |
| ISBN | : 0128202610 |
Biology of Aminoacyl-tRNA Synthetases, Volume 48 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on A narrative about our work on the endless frontier of editing, The puzzling evolution of aminoacyl-tRNA synthetases, Structural basis of the tRNA recognition by aminoacyl-tRNA synthetases, Catalytic strategies of aminoacyl-tRNA synthetases, Trans-editing by aminoacyl-tRNA synthetase-like editing domains, Adaptive and maladaptive mistranslation arising from aminoacyl-tRNA synthetases, Non-canonical inputs and outputs of tRNA aminoacylation, Structure and function of multi-tRNA synthetase complexes, Mitochondrial aminoacyl-tRNA synthetases, Non-canonical functions of human cytoplasmic tyrosyl-, tryptophanyl- and other aminoacyl-tRNA synthetases, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in The Enzymes series
| Author | : Ellen G. Strauss |
| Publisher | : Elsevier |
| Total Pages | : 476 |
| Release | : 2007-09-21 |
| Genre | : Medical |
| ISBN | : 0080553168 |
Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss' virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. - Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information - Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia - Further reading sections at the end of each chapter make it easy find key references - World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
| Author | : John Leonard Wilkinson |
| Publisher | : |
| Total Pages | : 324 |
| Release | : 1992 |
| Genre | : Medical |
| ISBN | : |
Neuroanatomy for Medical Students ...
| Author | : Paul Rea |
| Publisher | : Academic Press |
| Total Pages | : 178 |
| Release | : 2014-04-21 |
| Genre | : Science |
| ISBN | : 0128011874 |
Clinical Anatomy of the Cranial Nerves combines anatomical knowledge, pathology, clinical examination, and explanation of clinical findings, drawing together material typically scattered throughout anatomical textbooks. All of the pertinent anatomical topics are conveniently organized to instruct on anatomy, but also on how to examine the functioning of this anatomy in the patient. Providing a clear and succinct presentation of the underlying anatomy, with directly related applications of the anatomy to clinical examination, the book also provides unique images of anatomical structures of plastinated cadaveric dissections. These images are the only ones that exist in this form, and have been professionally produced in the Laboratory of Human Anatomy, University of Glasgow under the auspices of the author. These specimens offer a novel way of visualizing the cranial nerves and related important anatomical structures. Anatomy of cranial nerves described in text format with accompanying high-resolution images of professional, high-quality prosected cadaveric material, demonstrating exactly what the structures (and related ones) look like Succinct yet comprehensive format with quick and easy access to facts in clearly laid out key regions, common throughout the different cranial nerves Includes clinical examination and related pathologies, featuring diagnostic summaries of potential clinical presentations and clinically relevant questions on the anatomy of these nerves
| Author | : Mark Lyte |
| Publisher | : Springer |
| Total Pages | : 440 |
| Release | : 2014-07-05 |
| Genre | : Science |
| ISBN | : 1493908979 |
The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.
| Author | : Elena L. Paley |
| Publisher | : Academic Press |
| Total Pages | : 308 |
| Release | : 2021-03-13 |
| Genre | : Science |
| ISBN | : 0323884466 |
Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer's disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body. - Explores microbial metabolic pathways in the human body and implications for disease - Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways - Considers a variety of diseases and disorders, such as Alzheimer's disease, metabolic syndromes, Crohn's disease and Covid-19 - Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health
| Author | : Vasu D. Appanna |
| Publisher | : Springer |
| Total Pages | : 183 |
| Release | : 2018-02-05 |
| Genre | : Medical |
| ISBN | : 9811076847 |
This book offers a unique perspective on the invisible organ, a body part that has been visualized only recently. It guides the readers into the world of the microbial constituents that make humans the way they are. The vitamins they produce, the smell they generate, the signals they create, and the molecular guards they elaborate are some of the benefits they bestow on humans. After introducing the notion as to why microbes are an integral component in the development of humans, the book examines the genesis of the microbiome and describes how the resident bacteria work in partnership with the skin, digestive tract, sexual organs, mouth and lungs to execute vital physiological functions. It then discusses the diseases that are triggered by the disruption of the harmonious relationships amongst these diverse systems and provides microbial cures to ailments such as obesity and digestive complications. Finally, the book focuses on the future when the workings of the human microbes will be fully unravelled. Societal changes in health education, the establishment of the microbiome bank, the fight against hunger, space travel, designer traits and enhanced security are explained. Each chapter is accompanied by captivating illustrations and ends with a visual summary. Dr. Appanna has been researching for over 30 years on various aspects of microbial and human cellular systems. He is a professor of biochemistry and has also served as Department Chair and Dean of the Faculty at Laurentian University, Sudbury, Canada. The book is aimed at readers enrolled in medical, chiropractic, nursing, pharmacy, and health science programs. Practicing health-care professionals and continuing education learners will also find the content beneficial.
| Author | : Nathan Efron |
| Publisher | : |
| Total Pages | : 292 |
| Release | : 2004 |
| Genre | : Medical |
| ISBN | : |
The new 2nd edition of this practical manual has been completely updated and revised to reflect the most current knowledge, research findings, technological developments, and updates in contact lens materials. With its broad coverage and systematic approach, it provides an intuitive approach to understanding, diagnosing, and treating contact lens complications. This lavishly illustrated text is recognized as a definitive resource on contact lens for practitioners and students.
