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| Author | : Charles Emerson |
| Publisher | : Academic Press |
| Total Pages | : 521 |
| Release | : 1997 |
| Genre | : Medical |
| ISBN | : 0125641540 |
Methods in Muscle Biology is a comprehensive laboratory guide that details the methods used in the study of muscle biology. The techniques included embrace cell, developmental, and molecular biology, as well asphysiology, neurobiology, and medical research.
| Author | : Neil Spurway |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 285 |
| Release | : 2006-01-01 |
| Genre | : Medical |
| ISBN | : 0443100772 |
This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.
| Author | : Joseph J. Bass |
| Publisher | : Frontiers Media SA |
| Total Pages | : 145 |
| Release | : 2022-09-23 |
| Genre | : Science |
| ISBN | : 2832500676 |
| Author | : Michael Kyba |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2016-08-06 |
| Genre | : Science |
| ISBN | : 9781493938087 |
This volume focuses on the cell biology and physiology of skeletal muscle regeneration. This Book is a collection of classic and cutting edge protocols optimized for mice, but in most cases adaptable to rat or other mammalian models, that will allow an investigator to develop and implement a research study on skeletal muscle regeneration. Chapters address the three major areas of study: provoking regeneration by inducing damage to muscle, analyzing the progenitor cells of skeletal muscle, and quantifying overall muscle function. Subjects discussed include: inducing skeletal muscle injury by eccentric contraction; volumetric muscle loss; single myofiber isolation and culture; satellite cell transplantation; muscle clearing for whole mount immunostaining; luciferase tracking of muscle stem cells; mitochondrial and mitophagy flux analysis; in vivo assessment of muscle contractility; force measurements on single isolated myofibers; and analysis of aerobic respiration in intact skeletal muscle tissue by microplate respirometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to each respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Skeletal Muscle Regeneration in the Mouse: Methods and Protocols is an essential laboratory reference for research in skeletal muscle growth, damage, repair, degeneration, and regenerative therapy in the mouse model system.
| Author | : Camilla Bernardini |
| Publisher | : Humana Press |
| Total Pages | : 287 |
| Release | : 2017-10-25 |
| Genre | : Science |
| ISBN | : 9781493973736 |
This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on “Omics” techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.
| Author | : Joseph Hill |
| Publisher | : Academic Press |
| Total Pages | : 1469 |
| Release | : 2012-08 |
| Genre | : Medical |
| ISBN | : 012381510X |
Muscle: Fundamental Biology and Mechanisms of Disease will be the first reference covering cardiac, skeletal, and smooth muscle in fundamental, basic science, translational biology, disease mechanism, and therapeutics. Currently there are no publications covering the science behind the medicine, as the majority of books are 90% clinical and 10% science. Muscle: Fundamental Biology and Mechanisms of Disease will discuss myocyte biology, also known as muscle cell biology, providing information about the science behind clinical work and therapeutics with a 90% science and 10% clinical focus. A needed resource for researchers, clinical professionals, postdocs, and graduate students, this publication will further discuss basic biology development and physiology, how processes go awry in disease states, and how the defective pathways are targeted for therapy. This book will assist both the new and experienced clinician's and researcher's need for science translation of background research into clinical applications, bridging the gap between research and clinical knowledge.
| Author | : Sugi Haruo |
| Publisher | : |
| Total Pages | : 392 |
| Release | : 1998 |
| Genre | : Medical |
| ISBN | : |
Despite extensive physiological, biochemical, and structural studies, the mechanisms of muscle contraction operating in living muscle fibres are still not clearly understood. This book aims to describe and assess various experimental methods currently used in the field of muscle research. For each method discussed, there is a comprehensive description of its advantages, problems, and limitations. Each chapter also contains a summary of the central results to have been obtained using each method. Comprehensively written by experts in their respective fields, this book will be of interest to all investigators in muscle physiology.
| Author | : Jack A. Rall |
| Publisher | : Springer |
| Total Pages | : 480 |
| Release | : 2014-10-21 |
| Genre | : Medical |
| ISBN | : 1493920073 |
This book describes the evolution of ideas relating to the mechanism of muscular contraction since the discovery of sliding filaments in 1954. An amazing variety of experimental techniques have been employed to investigate the mechanism of muscular contraction and relaxation. Some background of these various techniques is presented in order to gain a fuller appreciation of their strengths and weaknesses. Controversies in the muscle field are discussed along with some missed opportunities and false trails. The pathway to ATP and the high energy phosphate bond will be discussed, as well as the discovery of myosin, contraction coupling and the emergence of cell and molecular biology in the muscle field. Numerous figures from original papers are also included for readers to see the data that led to important conclusions. This book is published on behalf of the American Physiological Society by Springer. Access to APS books published with Springer is free to APS members.
| Author | : Jerzy A. Zoladz |
| Publisher | : Academic Press |
| Total Pages | : 619 |
| Release | : 2018-11-05 |
| Genre | : Science |
| ISBN | : 0128145943 |
Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. - Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity - Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes - Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 384 |
| Release | : 1988-02-01 |
| Genre | : Medical |
| ISBN | : 0309037956 |
This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
