Metallothioneins And Related Chelators
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| Author | : Astrid Sigel |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 544 |
| Release | : 2015-07-24 |
| Genre | : Science |
| ISBN | : 3110436272 |
These sulfur-rich chelators, being important in metal ion homeostasis, find increasing attention. MILS-5, written by 30 internationally recognized experts, focuses on this hot topic. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. This book is an essential resource for scientists working in a wide range of disciplines from environmental toxicology and inorganic biochemistry all the way through to physiology and medicine.
| Author | : Y.P. Abrol |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 424 |
| Release | : 2013-06-29 |
| Genre | : Science |
| ISBN | : 9401702896 |
Sulphur (S) plays a pivotal role in various plant growth and development processes being a constituent of sulphur-containing amino acids, cysteine and methionine, and other metabolites viz., glutathione and phytochelatins, co-factor of enzymes which contribute to stress repair and amelioration of heavy metal toxicity. Besides, a number of S-containing components are biologically active and, thus, a source for use as medicinal value. The basic global issue before the agricultural scientist and world community is to evolve cultivars and develop methodologies for efficient use of inputs to enhance agricultural productivity. This is particularly true of the developing countries which are going to see maximum rise in population with changing food demands and declining availability of land. Amongst the inputs, nutrients play a crucial role. The major requirement is for N, P and K followed by several micro-nutrients. In this context reports of world-wide S deficiency in the agricultural systems are relevant. The reasons are many. Broadly speaking reduction inS emission, use of S-free N, P and K fertilizers and higher biomass production contributed the maximum. Despite the need for sulphur as an essential plant nutrient and the substantial returns expected from its use, very little attention has been given to fill the gap between supply and demand of S.
| Author | : Parvaiz Ahmad |
| Publisher | : Elsevier |
| Total Pages | : 654 |
| Release | : 2016-02-02 |
| Genre | : Technology & Engineering |
| ISBN | : 0128031832 |
Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. - Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants - Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation - Covers sustainable technologies in uptake and removal of heavy metals
| Author | : Astrid Sigel |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 603 |
| Release | : 2014-01-27 |
| Genre | : Science |
| ISBN | : 9400775008 |
MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.
| Author | : Rajendra Prasad |
| Publisher | : Cambridge Scholars Publishing |
| Total Pages | : 490 |
| Release | : 2024-02-26 |
| Genre | : Medical |
| ISBN | : 1527552675 |
This pioneering book offers a distinctive exploration of a previously uncharted realm; the book effectively amalgamates the fields of biochemistry, molecular biology, and molecular genetics concerning essential element-related genetic disorders, employing a coherent and logical approach. The result is a comprehensive guide to essential metals metabolism, covering their regulation, functions, and corresponding genetic disorders. It serves as an authoritative guide for a diverse audience, including medical students, medical nutritionists, medical geneticists, and basic medical scientists. This innovative perspective is particularly pertinent in an age where interdisciplinary collaboration is essential for comprehensive patient care and medical practice. By fostering a practice-centred approach in clinical medicine, the book will inspire clinicians to embrace a holistic viewpoint. Simultaneously, it beckons basic medical scientists to delve into the enigmatic domain of genetic disorders associated with essential elements.
| Author | : Lucia Banci |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 642 |
| Release | : 2013-04-18 |
| Genre | : Science |
| ISBN | : 9400755619 |
Metallomics and the Cell provides in an authoritative and timely manner in 16 stimulating chapters, written by 37 internationally recognized experts from 9 nations, and supported by more than 3000 references, several tables, and 110 illustrations, mostly in color, a most up-to-date view of the "metallomes" which, as defined in the "omics" world, describe the entire set of biomolecules that interact with or are affected by each metal ion. The most relevant tools for visualizing metal ions in the cell and the most suitable bioinformatic tools for browsing genomes to identify metal-binding proteins are also presented. Thus, MILS-12 is of relevance for structural and systems biology, inorganic biological chemistry, genetics, medicine, diagnostics, as well as teaching, etc.
| Author | : Astrid Sigel |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 608 |
| Release | : 2015-07-24 |
| Genre | : Science |
| ISBN | : 3110436604 |
Volume 7, devoted to the vital and rapidly expanding research area around metal-carbon bonds (see also MILS-6), focuses on the environment. With more than 2500 references, 35 tables, and nearly 50 illustrations, many of these in color, it is an essential resource for scientists working in the wide range from organometallic chemistry, inorganic biochemistry, environmental toxicology all the way through to physiology and medicine. In 14 stimulating chapters, written by 29 internationally recognized experts, Organometallics in Environment and Toxicology highlights in an authoritative and timely manner environmental cycles of elements involving organometal(loid) compounds as well as the analytical determination of such species. This book examines methane formation involving the nickel coenzyme F430, as well as the organometal(loid) compounds formed by tin, lead, arsenic, antimony, bismuth, selenium, tellurium, and mercury. In addition, it deals with the environmental bioindication, biomonitoring, and bioremediation of organometal(loid)s, and it terminates with methylated metal(loid) species occurring in humans by evaluating assumed and proven health effects caused by these compounds.
| Author | : Rudolfs K. Zalups |
| Publisher | : CRC Press |
| Total Pages | : 442 |
| Release | : 2010-05-21 |
| Genre | : Medical |
| ISBN | : 142005998X |
With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses
| Author | : Astrid Sigel |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 386 |
| Release | : 2012-01-02 |
| Genre | : Science |
| ISBN | : 9400721722 |
Interplay between Metal Ions and Nucleic Acids provides in an authoritative and timely manner in 12 stimulating chapters, written by 24 internationally recognized experts from 8 nations, and supported by nearly 1500 references, about 20 tables, and 125 illustrations, many in color, a most up-to-date view on metal ion-nucleic acid interactions; the characterization of which is covered in solution and in the solid state. The volume concentrates on modern developments encompassing topics in the wide range from G-quadruplexes via DNAzymes, catalysis at the DNA scaffold, and metal-mediated base pairs to peptide nucleic acids (PNAs) being thus of relevance, e.g., for chemistry and nanotechnology but also for molecular biology and (genetic) diagnostics.
| Author | : Robert R. Crichton |
| Publisher | : Elsevier |
| Total Pages | : 383 |
| Release | : 2007-12-11 |
| Genre | : Science |
| ISBN | : 0080556221 |
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters
