Metabolic and Vascular Imaging Biomarkers for Brain Aging and Alzheimer’s Disease
| Author | : Ai-Ling Lin |
| Publisher | : Frontiers Media SA |
| Total Pages | : 242 |
| Release | : 2020-08-10 |
| Genre | : Science |
| ISBN | : 2889639053 |
Metabolic And Vascular Imaging Biomarkers For Brain Aging And Alzheimers Disease
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Neuroanatomy and Pathology of Sporadic Alzheimer's Disease
| Author | : Heiko Braak |
| Publisher | : Springer |
| Total Pages | : 168 |
| Release | : 2014-12-11 |
| Genre | : Medical |
| ISBN | : 3319126792 |
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail
Biomarkers in Alzheimer's Disease
| Author | : Tapan Khan |
| Publisher | : Academic Press |
| Total Pages | : 278 |
| Release | : 2016-08-02 |
| Genre | : Psychology |
| ISBN | : 0128051477 |
Biomarkers in Alzheimer's Disease provides a comprehensive overview of all modalities of Alzheimer's disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer's disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer's disease, and for differential diagnosis of Alzheimer's disease with other non-Alzheimer's dementia. - Presents a comprehensive overview detailing all modalities of Alzheimer's disease biomarkers - Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer's Disease - Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer's disease and the technological advancement of biomarkers techniques
Neuroimaging in Dementia
| Author | : Frederik Barkhof |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 295 |
| Release | : 2011-02-11 |
| Genre | : Medical |
| ISBN | : 3642008186 |
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with cognitive decline. It sets out the key clinical and imaging features of the various causes of dementia and directs the reader from clinical presentation to neuroimaging and on to an accurate diagnosis whenever possible. After an introductory chapter on the clinical background, the available "toolbox" of structural and functional neuroimaging techniques is reviewed in detail, including CT, MRI and advanced MR techniques, SPECT and PET, and image analysis methods. The imaging findings in normal ageing are then discussed, followed by a series of chapters that carefully present and analyze the key findings in patients with dementias. Throughout, a practical approach is adopted, geared specifically to the needs of clinicians (neurologists, radiologists, psychiatrists, geriatricians) working in the field of dementia, for whom this book will prove an invaluable resource.
Ageing and Dementia
| Author | : Kurt Jellinger |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 400 |
| Release | : 2002-08-20 |
| Genre | : Gardening |
| ISBN | : 9783211837979 |
Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Cerebrospinal Fluid Biomarkers
| Author | : Charlotte E. Teunissen |
| Publisher | : Humana |
| Total Pages | : 236 |
| Release | : 2022-05-19 |
| Genre | : Medical |
| ISBN | : 9781071613214 |
This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.
Diseases of the Brain, Head and Neck, Spine 2020–2023
| Author | : Juerg Hodler |
| Publisher | : Springer Nature |
| Total Pages | : 252 |
| Release | : 2020-02-14 |
| Genre | : Medical |
| ISBN | : 303038490X |
This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Cognitive Changes and the Aging Brain
| Author | : Kenneth M. Heilman |
| Publisher | : Cambridge University Press |
| Total Pages | : |
| Release | : 2019-12-05 |
| Genre | : Medical |
| ISBN | : 1108688497 |
This book describes the changes in the brain and in cognitive functions that occur with aging in the absence of a neurological, psychiatric, or medical disease. It discusses aging-related changes in many brain functions, including memory, language, sensory perception, motor function, creativity, attention, executive functions, emotions and mood. The neural mechanisms that may account for specific aging-related changes in cognition, perception and behavior are explored, as well as the means by which aging-related cognitive decrements can be managed and possibly ameliorated. Consequently, this book will be of value to clinicians, including neurologists, psychiatrists, geriatricians, primary care physicians, psychologists and speech-language pathologists. In addition, researchers and graduate students who want to learn about the aging brain will find this an indispensable guide.
Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment
| Author | : David J. Libon |
| Publisher | : |
| Total Pages | : 505 |
| Release | : 2020 |
| Genre | : Health & Fitness |
| ISBN | : 0190634235 |
"Cerebrovascular and Alzheimer disease often occur together, but are usually studied apart. This book offers a timely integrated approach to both diseases. Beginning with a section on epidemiology and neuropsychology, this volume goes on to discuss and explore the neuropathological and neurophysiological mechanisms of these disorders. This book then develops a novel concept of an Alzheimer disease/vascular dementia spectrum. Sections on neuroimaging, as well as treatments and interventions follow. The editors have succeeded in gathering an impressive group of clinicians and scientists, who are well qualified by their achievements and leadership to make important contributions to this new integrated approach to dementing disorders. This important book should have broad appeal to anyone studying or caring for patients with dementing disorders, as it is comprehensive, yet focused on a unitary, complementary and pragmatic approach"--
Limbic-predominant Age-related TDP-43 Encephalopathy
| Author | : Beller Health |
| Publisher | : Independently Published |
| Total Pages | : 114 |
| Release | : 2019-05-13 |
| Genre | : |
| ISBN | : 9781097268511 |
Book 9 focuses on a new dementia type, LATE, mistaken as Alzheimer's disease until now.LATE stands for Limbic-predominant age-related TDP-43 encephalopathy, the protein buildup responsible for this dementia. This book is organic, like the series, meaning we never consider our books as finished. Science evolves, which is why our books go through continuous updates. Since LATE is a new dementia classification, we expect continuous further information to emerge. Watch Amazon alerts for potential digital updates. We provide free digital copies on all paperback purchases, so everybody receives free updates.
