Mass Spectrometry of Biological Materials, Second Edition

Mass Spectrometry of Biological Materials, Second Edition
Author: Barbara S. Larsen
Publisher: CRC Press
Total Pages: 490
Release: 1998-03-02
Genre: Science
ISBN: 9780824701574

Second Edition provides up-to-the-minute discussions on the application of mass spectrometry to the biological sciences. Shows how and why experiments are performed and furnishes details to facilitate duplication of results.

ToF-SIMS

ToF-SIMS
Author: J. C. Vickerman
Publisher: IM Publications
Total Pages: 742
Release: 2013
Genre: Mass spectrometry
ISBN: 1906715173

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is the most versatile of the surface analysis techniques that have been developed during the last 30 years. This is the Second Edition of the first book ToF-SIMS: Surface analysis by Mass Spectrometry to be dedicated to the subject and the treatment is comprehensive

Mass Spectrometry

Mass Spectrometry
Author: Edmond de Hoffmann
Publisher: Wiley
Total Pages: 420
Release: 2001-10-10
Genre: Science
ISBN: 9780471485650

Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Handbook Of Biomaterials Evaluation

Handbook Of Biomaterials Evaluation
Author: Andreas F von Recum
Publisher: CRC Press
Total Pages: 944
Release: 1998-12-18
Genre: Medical
ISBN: 9781560324799

This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials.

Infrared and Raman Spectroscopy of Biological Materials

Infrared and Raman Spectroscopy of Biological Materials
Author: Hans-Ulrich Gremlich
Publisher: CRC Press
Total Pages: 604
Release: 2000-09-25
Genre: Science
ISBN: 9780824704094

Infrared and Raman Spectroscopy of Biological Materials facilitates a comprehensive and through understanding of the latest developments in vibrational spectroscopy. It contains explains key breakthroughs in the methodologies and techniques for infrared, near-infrared, and Raman spectroscopy. Topics include qualitative and quantitative analysis, biomedical applications, vibrational studies of enzymatic catalysis, and chemometrics.

Chemical Genomics and Proteomics, Second Edition

Chemical Genomics and Proteomics, Second Edition
Author: Ferenc Darvas
Publisher: CRC Press
Total Pages: 247
Release: 2013-01-11
Genre: Medical
ISBN: 1439830525

Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplinary feature as well as the remarkable developments that have occurred. The new edition also covers innovative applications from cell biology to drug discovery to, more recently, clinical diagnostics and medical practice, which utilize the concepts of chemical genomics. The text provides an overview of the strategies and methodologies of chemical genomics, focusing on emerging technologies and recent applications in the areas of combination chemical genetics, toxicogenomics, drug chemical genomics and proteomics, and orthogonal chemical genetics. It describes the development and application of novel analytical methods used in lipodomics, such as steroidomics. The book also discusses biomarker discovery applications of microarray technologies using DNA, RNA, and protein and glycan arrays. Chapters cover further applications of biomolecular biomarkers for disease diagnosis, in small molecule drug R&D, and during therapeutic use of medicines. These include prognostic, disease specific, response (surrogate), and toxicity biomarkers. In addition, the text explores the principles of contemporary systems biology and genomics in experimental medicine—a new paradigm that demonstrates a network-oriented view and advanced statistical and informatics data management, opening the way toward personalized medicine. Finally, various in silico chemogenomics approaches are addressed for predicting binding of drug candidates to undesirable targets, which would help in designing better clinical candidates with fewer side effects. This new edition benefits a broad range of readers from industrial and academic researchers in drug discovery, medicinal chemistry, and molecular and cell biology to physicians in clinical diagnostics and students in related fields of study.

Introduction to Mass Spectrometry

Introduction to Mass Spectrometry
Author: J. Throck Watson
Publisher: John Wiley & Sons
Total Pages: 972
Release: 2013-07-09
Genre: Science
ISBN: 1118681584

Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry

Measuring Mass

Measuring Mass
Author: Michael A. Grayson
Publisher: Chemical Heritage Foundation
Total Pages: 164
Release: 2002
Genre: Science
ISBN: 9780941901314

Measuring Mass: From Positive Rays to Proteins is part of a celebration of fifty years of the Annual Conference on Mass Spectrometry and Allied Topics. As such, it is intended not only for practitioners of mass spectrometry but also for the lay reader interested in knowing more about the field. Many who practice the art and science of mass spectrometry are unaware of how the technique is applied outside their particular area of expertise. This short exposition will provide the practitioner and lay reader alike with an appreciation for the diverse applications of mass spectrometry in present-day scientific endeavors. Measuring Mass is also intended to celebrate the major events in the history of mass spectrometry. While a complete history of the field would require a tome of much greater size, this book provides a flavor of how mass spectrometry developed from an early-20th-century curiosity of the physics laboratory into the powerful analytical tool of today. The intertwined stories of advances in the technology and instrumentation of mass spectrometry with the demand to extend the tool to more complex analytical problems are explored in chapters on applications in geology, chemistry, biology, pharmaceuticals, space, the environment and forensic science.

Mass Spectrometry

Mass Spectrometry
Author: Edmond de Hoffmann
Publisher: John Wiley & Sons
Total Pages: 502
Release: 2013-04-03
Genre: Science
ISBN: 1118681940

The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.

Handbook of Near-Infrared Analysis, Second Edition

Handbook of Near-Infrared Analysis, Second Edition
Author: Donald A. Burns
Publisher: CRC Press
Total Pages: 834
Release: 2001-06-28
Genre: Science
ISBN: 9781420002577

With contributions from over 40 experts in the field, this reference presents comprehensive, single-source coverage of the instrumentation, computerization, calibration, and methods development of NIR spectroscopy. It provides novel applications for accurate time- and cost-effective analyses of pharmaceuticals, polymers, textiles, agricultural products, dairy products, foods, and beverages. Emphasizing trends in sample preparation, the book covers historical development, calibration transfer, biomedical applications, plastics, and counterfeiting; on-line, in-line, and at-line analyses for process control, multilinear regression and principal component analysis, and more.