Manuscript Genetics
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| Author | : Dirk van Hulle |
| Publisher | : |
| Total Pages | : 260 |
| Release | : 2008 |
| Genre | : Literary Criticism |
| ISBN | : |
By taking the principles of manuscript genetics and using them to engage in a comparative study of James Joyce and Samuel Beckett, Dirk Van Hulle has produced a provocative work that re-imagines the links between the two authors. His elegant readings reveal that the most striking similarities between these two lie not in their nationality or style but in their shared fascination with the process of revision. Van Hulle's thoughtful application of genetic theory--the study of a work from manuscript to final form in its various iterations--marks a new phase in this dynamic field of inquiry. As one of only a handful of books in English dealing with this emerging area of study, Manuscript Genetics, Joyce's Know-How, Beckett's Nohow will be indispensable not only to Joyce and Beckett scholars but also to anyone interested in genetic criticism.
| Author | : Lily E. Kay |
| Publisher | : Stanford University Press |
| Total Pages | : 476 |
| Release | : 2000 |
| Genre | : Science |
| ISBN | : 9780804734172 |
This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technologyand consequently as a book of life. This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the book of life metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic book of life.
| Author | : Elise K. Burton |
| Publisher | : Stanford University Press |
| Total Pages | : 464 |
| Release | : 2021-01-26 |
| Genre | : History |
| ISBN | : 1503614573 |
The Middle East plays a major role in the history of genetic science. Early in the twentieth century, technological breakthroughs in human genetics coincided with the birth of modern Middle Eastern nation-states, who proclaimed that the region's ancient history—as a cradle of civilizations and crossroads of humankind—was preserved in the bones and blood of their citizens. Using letters and publications from the 1920s to the present, Elise K. Burton follows the field expeditions and hospital surveys that scrutinized the bodies of tribal nomads and religious minorities. These studies, geneticists claim, not only detect the living descendants of biblical civilizations but also reveal the deeper past of human evolution. Genetic Crossroads is an unprecedented history of human genetics in the Middle East, from its roots in colonial anthropology and medicine to recent genome sequencing projects. It illuminates how scientists from Turkey to Yemen, Egypt to Iran, transformed genetic data into territorial claims and national origin myths. Burton shows why such nationalist appropriations of genetics are not local or temporary aberrations, but rather the enduring foundations of international scientific interest in Middle Eastern populations to this day.
| Author | : Sahotra Sarkar |
| Publisher | : Rowman & Littlefield |
| Total Pages | : 225 |
| Release | : 2021-09-15 |
| Genre | : Science |
| ISBN | : 1786614391 |
The emergence of CRISPR/Cas9 technology has revolutionized gene editing. The Nobel prize for chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna, the scientists responsible for its discovery, in 2020 and it is considered the frontier of sophisticated medical science. This technology contains the promise that both gene therapy and eugenic control of human evolution is possible, even plausible, in our near future. This book looks at these developements in the context of the history of previous social and scientific attempts at genetic editing, and explores the policy and ethical challenges they raise. It presents the case for altering the human germ-line (which contains and controls hereditary genetic information) to eliminate a large number of genetic diseases controlled by a single or few genes, while pointing out that gene therapy is likely to be ineffective for diseases with more complex causes. In parallel it explores the possibility of genetic enhancement in a set of case studies. But it also argues that, in general, genetic enhancement is ethically problematic and should be approached with caution. Given the success of CRISPR/Cas9 gene editing, and the explosion of related techniques, in practice it would be virtually impossible to ban germ-line editing in our future. A more useful goal is to put regulation in place, with oversight that represents the interests of society. That, in turn, requires an informed public discussion of these issues, which is the intention of this book.
| Author | : Hans Walter Gabler |
| Publisher | : Open Book Publishers |
| Total Pages | : 242 |
| Release | : 2018-02-20 |
| Genre | : Literary Criticism |
| ISBN | : 1783743662 |
This collection of essays from world-renowned scholar Hans Walter Gabler contains writings from a decade and a half of retirement spent exploring textual criticism, genetic criticism, and literary criticism. In these sixteen stimulating contributions, he develops theories of textual criticism and editing that are inflected by our advance into the digital era; structurally analyses arts of composition in literature and music; and traces the cultural implications discernible in book design, and in the canonisation of works of literature and their authors. Distinctive and ambitious, these essays move beyond the concerns of the community of critics and scholars. Gabler responds innovatively to the issues involved and often endeavours to re-think their urgencies by bringing together the orthodox tenets of different schools of textual criticism. He moves between a variety of topics, ranging from fresh genetic approaches to the work of James Joyce and Virginia Woolf, to significant contributions to the theorisation of scholarly editing in the digital age. Written in Gabler’s fluent style, these rich and elegant compositions are essential reading for literary and textual critics, scholarly editors, readers of James Joyce, New Modernism specialists, and all those interested in textual scholarship and digital editing under the umbrella of Digital Humanities.
| Author | : Fred W. Allendorf |
| Publisher | : John Wiley & Sons |
| Total Pages | : 636 |
| Release | : 2012-12-17 |
| Genre | : Science |
| ISBN | : 0470671459 |
Loss of biodiversity is among the greatest problems facing the world today. Conservation and the Genetics of Populations gives a comprehensive overview of the essential background, concepts, and tools needed to understand how genetic information can be used to conserve species threatened with extinction, and to manage species of ecological or commercial importance. New molecular techniques, statistical methods, and computer programs, genetic principles, and methods are becoming increasingly useful in the conservation of biological diversity. Using a balance of data and theory, coupled with basic and applied research examples, this book examines genetic and phenotypic variation in natural populations, the principles and mechanisms of evolutionary change, the interpretation of genetic data from natural populations, and how these can be applied to conservation. The book includes examples from plants, animals, and microbes in wild and captive populations. This second edition contains new chapters on Climate Change and Exploited Populations as well as new sections on genomics, genetic monitoring, emerging diseases, metagenomics, and more. One-third of the references in this edition were published after the first edition. Each of the 22 chapters and the statistical appendix have a Guest Box written by an expert in that particular topic (including James Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, and Lisette Waits). This book is essential for advanced undergraduate and graduate students of conservation genetics, natural resource management, and conservation biology, as well as professional conservation biologists working for wildlife and habitat management agencies. Additional resources for this book can be found at: www.wiley.com/go/allendorf/populations.
| Author | : Catherine Bliss |
| Publisher | : Stanford University Press |
| Total Pages | : 359 |
| Release | : 2018-01-16 |
| Genre | : Social Science |
| ISBN | : 1503603962 |
Sociogenomics has rapidly become one of the trendiest sciences of the new millennium. Practitioners view human nature and life outcomes as the result of genetic and social factors. In Social by Nature, Catherine Bliss recognizes the promise of this interdisciplinary young science, but also questions its implications for the future. As she points out, the claim that genetic similarities cause groups of people to behave in similar ways is not new—and a dark history of eugenics warns us of its dangers. Over the last decade, sociogenomics has enjoyed a largely uncritical rise to prominence and acceptance in popular culture. Researchers have published studies showing that things like educational attainment, gang membership, and life satisfaction are encoded in our DNA long before we say our first word. Strangely, unlike the racial debates over IQ scores in the '70s and '90s, sociogenomics has not received any major backlash. By exposing the shocking parallels between sociogenomics and older, long-discredited, sciences, Bliss persuasively argues for a more thoughtful public reception of any study that reduces human nature to a mere sequence of genes. This book is a powerful call for researchers to approach their work in more socially responsible ways, and a must-read for anyone who wants to better understand the scholarship that impacts how we see ourselves and our society.
| Author | : S D Gangane |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 293 |
| Release | : 2021-04-15 |
| Genre | : Medical |
| ISBN | : 8131262103 |
The sixth edition of this book is revised as per guidelines of National Medical Commission in accordance with the competency-based curriculum of Genetics. This book forms a concise version chiefly designed to cater to the needs of undergraduate students. The aim has been to offer the basic principles without superfluous details. • Text is presented in a simple and precise manner, with complex information summarized in tables and line diagrams, which makes the learning easier for students. • Presentation is visually more appealing with the insertion of clinical pictures along with the text. • Recapitulation of summary at the end of chapters would also help students to quickly review and revise the subject before examination. • Questions given at the end of each chapter along with answers for self-assessment of the topics studied. • Prepares students for both theory and viva voce. Salient Features • Text is presented in a simple and precise manner, with complex information summarized in tables and line diagrams, which makes the learning easier for students. • Presentation is visually more appealing with the insertion of clinical pictures along with the text. • Recapitulation of summary at the end of chapters would also help students to quickly review and revise the subject before examination. • Questions given at the end of each chapter along with answers for self-assessment of the topics studied. • Prepares students for both theory and viva voce. Online Resources Complimentary access to full e-book along with animations at www.medenact.com
| Author | : Yii-Jan Lin |
| Publisher | : Oxford University Press |
| Total Pages | : 219 |
| Release | : 2016 |
| Genre | : Religion |
| ISBN | : 019027980X |
New Testament textual critics who used language to group texts into families and genealogies were not pioneering new approaches, but rather borrowing the metaphors and methods of natural scientists. Texts began to be classified into "families, tribes, and nations," and later were racialized as "African" or "Asian," with distinguishable "textual physiognomies" and "textual complexions." These genealogies would later be traced to show the inheritance of "corruptions" and "contamination" through generations, an understanding of textual diversity reflective of eighteenth- and ninteenth-century European anxieties over racial corruption and degeneration. While these biological metaphors have been powerful tools for textual critics, they also produce problematic understandings of textual "purity" and agency, with the use of scientific discourse artificially separating the work of textual criticism from literary interpretation.
| Author | : S D Gangane |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 313 |
| Release | : 2012-04-25 |
| Genre | : Medical |
| ISBN | : 813124606X |
This 4th edition is thoroughly updated version of the 3rd edition with its intact simple to-the-point presentation of knowledge, which makes the book examination friendly. This edition will be useful not only to the undergraduates, but also to the postgraduates, immunologists and geneticists. - A chapter on "Stem Cell Therapy" - Inclusion of Summary at the end of each chapter - The concept of personalized medicine under Pharmacogenetics - Information updation in nearly all chapters - A chapter on "Stem Cell Therapy" - Inclusion of Summary at the end of each chapter - The concept of personalized medicine under Pharmacogenetics - Information updation in nearly all chapters
