Data Analysis for the Life Sciences with R

Data Analysis for the Life Sciences with R
Author: Rafael A. Irizarry
Publisher: CRC Press
Total Pages: 537
Release: 2016-10-04
Genre: Mathematics
ISBN: 1498775861

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

Deep Learning for the Life Sciences

Deep Learning for the Life Sciences
Author: Bharath Ramsundar
Publisher: O'Reilly Media
Total Pages: 236
Release: 2019-04-10
Genre: Science
ISBN: 1492039802

Deep learning has already achieved remarkable results in many fields. Now it’s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields. Ideal for practicing developers and scientists ready to apply their skills to scientific applications such as biology, genetics, and drug discovery, this book introduces several deep network primitives. You’ll follow a case study on the problem of designing new therapeutics that ties together physics, chemistry, biology, and medicine—an example that represents one of science’s greatest challenges. Learn the basics of performing machine learning on molecular data Understand why deep learning is a powerful tool for genetics and genomics Apply deep learning to understand biophysical systems Get a brief introduction to machine learning with DeepChem Use deep learning to analyze microscopic images Analyze medical scans using deep learning techniques Learn about variational autoencoders and generative adversarial networks Interpret what your model is doing and how it’s working

Physics of the Life Sciences

Physics of the Life Sciences
Author: Jay Newman
Publisher: Springer Science & Business Media
Total Pages: 721
Release: 2010-03-23
Genre: Science
ISBN: 0387772596

Each chapter has three types of learning aides for students: open-ended questions, multiple-choice questions, and quantitative problems. There is an average of about 50 per chapter. There are also a number of worked examples in the chapters, averaging over 5 per chapter, and almost 600 photos and line drawings.

Global Transformations in the Life Sciences, 1945–1980

Global Transformations in the Life Sciences, 1945–1980
Author: Patrick Manning
Publisher: University of Pittsburgh Press
Total Pages: 292
Release: 2018-06-07
Genre: Science
ISBN: 0822986051

The second half of the twentieth century brought extraordinary transformations in knowledge and practice of the life sciences. In an era of decolonization, mass social welfare policies, and the formation of new international institutions such as UNESCO and the WHO, monumental advances were made in both theoretical and practical applications of the life sciences, including the discovery of life’s molecular processes and substantive improvements in global public health and medicine. Combining perspectives from the history of science and world history, this volume examines the impact of major world-historical processes of the postwar period on the evolution of the life sciences. Contributors consider the long-term evolution of scientific practice, research, and innovation across a range of fields and subfields in the life sciences, and in the context of Cold War anxieties and ambitions. Together, they examine how the formation of international organizations and global research programs allowed for transnational exchange and cooperation, but in a period rife with competition and nationalist interests, which influenced dramatic changes in the field as the postcolonial world order unfolded.

Writing in the Life Sciences

Writing in the Life Sciences
Author: Laurence S. Greene
Publisher: Oxford University Press, USA
Total Pages: 482
Release: 2010-01-01
Genre: Science
ISBN: 9780195170467

Practicing scientists know that the quality of their livelihood is strongly connected to the quality of their writing, and critical thinking is the most necessary and valuable tool for effectively generating and communicating scientific information. Writing in the Life Sciences is an innovative, process-based text that gives beginning writers the tools to write about science skillfully by taking a critical thinking approach. Laurence Greene emphasizes "writing as thinking" as he takes beginning writers through the important stages of planning, drafting, and revising their work. Throughout, he uses focused and systematic critical reading and thinking activities to help scientific writers develop the skills to effectively communicate. Each chapter addresses a particular writing task rather than a specific type of document. The book makes clear which tasks are important for all writing projects (i.e., audience analysis, attending to instructions) and which are unique to a specific writing project (rhetorical goals for each type of document). Ideal for Scientific Writing courses and writing-intensive courses in various science departments (e.g., Biology, Environmental Studies, etc.), this innovative, process-based text goes beyond explaining what scientific writing is and gives students the tools to do it skillfully.

Dual Use Research of Concern in the Life Sciences

Dual Use Research of Concern in the Life Sciences
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 115
Release: 2017-10-01
Genre: Science
ISBN: 0309458889

The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.

Model Based Inference in the Life Sciences

Model Based Inference in the Life Sciences
Author: David R. Anderson
Publisher: Springer Science & Business Media
Total Pages: 203
Release: 2007-12-22
Genre: Science
ISBN: 0387740759

This textbook introduces a science philosophy called "information theoretic" based on Kullback-Leibler information theory. It focuses on a science philosophy based on "multiple working hypotheses" and statistical models to represent them. The text is written for people new to the information-theoretic approaches to statistical inference, whether graduate students, post-docs, or professionals. Readers are however expected to have a background in general statistical principles, regression analysis, and some exposure to likelihood methods. This is not an elementary text as it assumes reasonable competence in modeling and parameter estimation.

Planning a Career in Biomedical and Life Sciences

Planning a Career in Biomedical and Life Sciences
Author: Avrum I. Gotlieb
Publisher: Academic Press
Total Pages: 144
Release: 2014-12-08
Genre: Science
ISBN: 0128025700

Planning a Career in Biomedical and Life Sciences presents useful information, insights, and tips to those pursuing a career in the biomedical and life sciences. The book focuses on making educated choices during schooling, training, and job searching in both the academic and non-academic sectors. The premise of Planning a Career in Biomedical and Life Sciences is that by understanding the full path of a career in either the biomedical or life science fields, you can proactively plan your career, recognize any opportunities that present themselves, and be well prepared to address important aspects of your own professional development. Topics include choosing your training path, selecting the best supervisor/mentor, and negotiating a job offer. Provides strategies on evaluating biomedical and life sciences education and professional development opportunities in a thorough and systematic fashion. Discusses possible pitfalls and offers insight into how to navigate them successfully at various points of a scientist’s career. Offers valuable advice on how to make the best choices for yourself at any stage in your career.

Valuation in Life Sciences

Valuation in Life Sciences
Author: Boris Bogdan
Publisher: Springer Science & Business Media
Total Pages: 378
Release: 2010-04-19
Genre: Business & Economics
ISBN: 3642108202

Valuation is a hot topic among life sciences professionals. There is no clear understanding on how to use the different valuation approaches and how to determine input parameters. Some do not value at all, arguing that it is not possible to get realistic and objective numbers out of it. Some claim it to be an art. In the following chapters we will provide the user with a concise val- tion manual, providing transparency and practical insight for all dealing with valuation in life sciences: project and portfolio managers, licensing executives, business developers, technology transfer managers, entrep- neurs, investors, and analysts. The purpose of the book is to explain how to apply discounted cash flow and real options valuation to life sciences p- jects, i.e. to license contracts, patents, and firms. We explain the fun- mentals and the pitfalls with case studies so that the reader is capable of performing the valuations on his own and repeat the theory in the exercises and case studies. The book is structured in five parts: In the first part, the introduction, we discuss the role of the players in the life sciences industry and their p- ticular interests. We describe why valuation is important to them, where they need it, and the current problems to it. The second part deals with the input parameters required for valuation in life sciences, i.e. success rates, costs, peak sales, and timelines.

Managing Discovery in the Life Sciences

Managing Discovery in the Life Sciences
Author: Philip A. Rea
Publisher: Cambridge University Press
Total Pages: 557
Release: 2018-02
Genre: Business & Economics
ISBN: 1107130905

Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.