Imidazole and Benzimidazole Synthesis

Imidazole and Benzimidazole Synthesis
Author: M. R. Grimmett
Publisher: Academic Press
Total Pages: 289
Release: 1997-06-02
Genre: Science
ISBN: 0080534457

Imidazole and Benzimidazole Synthesis is a comprehensive survey of the known methods of syntheses and ring modification. It brings together the multitude of synthesis of the imidazole ring in a systemic way interms of specific bond formation, and recommends the most attractive synthetic approaches. It also collects non-ring-synthetic approaches to classes of compounds such as nitro-, halogeno-, and amino-imidazoles, and covers the synthesis of N-substituted compounds and preparations of specific isomers. The only book in print dealing specifically with this topic Comprehensive survey of the known methods of synthesis and ring modification Recommends the most attractive synthetic approaches

Organic Reaction Mechanisms 2015

Organic Reaction Mechanisms 2015
Author: A. C. Knipe
Publisher: John Wiley & Sons
Total Pages: 717
Release: 2019-02-08
Genre: Science
ISBN: 1119125065

Organic Reaction Mechanisms 2015, the 51st annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2015. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.

Modern Arylation Methods

Modern Arylation Methods
Author: Lutz Ackermann
Publisher: John Wiley & Sons
Total Pages: 561
Release: 2009-04-22
Genre: Science
ISBN: 3527627332

Today, arylation methods are belonging to the most important reaction types in organic synthesis. Lutz Ackermann, a young and ambitious professor has gathered a number of top international authors to present the first comprehensive book on the topic. Starting from a historical review, the book covers hot topics like Palladium-catalyzed arylation of N-H and alpha-C-H-acidic Bonds, Copper-catalyzed arylation of N-H and O-H Bonds, direct arylation reactions, carbanion aromatic synthesis, arylation reactions of alkenes, alkynes and much more. This compact source of high quality information is indispensable to synthetic chemists and those working in the pharmaceutical and chemical industry.

Green Chemistry and Catalysis

Green Chemistry and Catalysis
Author: R. A. Sheldon
Publisher: John Wiley & Sons
Total Pages: 448
Release: 2007-06-27
Genre: Science
ISBN: 3527611010

This first book to focus on catalytic processes from the viewpoint of green chemistry presents every important aspect: · Numerous catalytic reductions and oxidations methods · Solid-acid and solid-base catalysis · C-C bond formation reactions · Biocatalysis · Asymmetric catalysis · Novel reaction media like e.g. ionic liquids, supercritical CO2 · Renewable raw materials Written by Roger A. Sheldon -- without doubt one of the leaders in the field with much experience in academia and industry -- and his co-workers, the result is a unified whole, an indispensable source for every scientist looking to improve catalytic reactions, whether in the college or company lab.

Iron Catalysis

Iron Catalysis
Author: Bernd Plietker
Publisher: Springer Science & Business Media
Total Pages: 227
Release: 2011-01-05
Genre: Science
ISBN: 3642146694

Juan I. Padrón and Víctor S. Martín: Catalysis by means of Fe-based Lewis acids; Hiroshi Nakazawa*, Masumi Itazaki: Fe–H Complexes in Catalysis; Kristin Schröder, Kathrin Junge, Bianca Bitterlich, and Matthias Beller: Fe-catalyzed Oxidation Reactions of Olefins, Alkanes and Alcohols: Involvement of Oxo- and Peroxo Complexes; Chi-Ming Che, Cong-Ying Zhou, Ella Lai-Ming Wong: Catalysis by Fe=X Complexes (X=NR, CR2); René Peters, Daniel F. Fischer and Sascha Jautze: Ferrocene and Half Sandwich Complexes as Catalysts with Iron Participation; Markus Jegelka, Bernd Plietker: Catalysis by Means of Complex Ferrates.

N-Heterocyclic Carbenes

N-Heterocyclic Carbenes
Author: Silvia Diez-Gonzalez
Publisher: Royal Society of Chemistry
Total Pages: 637
Release: 2016-11-04
Genre: Science
ISBN: 1782626816

In less than 20 years N-heterocyclic carbenes (NHCs) have become well-established ancillary ligands for the preparation of transition metal-based catalysts. This is mainly due to the fact that NHCs tend to bind strongly to metal centres, avoiding the need of excess ligand in catalytic reactions. Also, NHC‒metal complexes are often insensitive to air and moisture, and have proven remarkably resistant to oxidation. This book showcases the wide variety of applications of NHCs in different chemistry fields beyond being simple phosphine mimics. This second edition has been updated throughout, and now includes a new chapter on NHC‒main group element complexes. It covers the synthesis of NHC ligands and their corresponding metal complexes, as well as their bonding and stereoelectronic properties and applications in catalysis. This is complemented by related topics such as organocatalysis and biologically active complexes. Written for organic and inorganic chemists, this book is ideal for postgraduates, researchers and industrialists.

Green Chemistry

Green Chemistry
Author: Paul T. Anastas
Publisher: Oxford University Press, USA
Total Pages: 135
Release: 2000-01-01
Genre: Science
ISBN: 9780198506980

''As the summary of a vision, the book is brilliant. One can feel the enthusiasm of the authors throughout...I see it as a vehicle for initiating a fruitful dialogue between chemical producers and regulatory enforcers without the confrontation, which often characterizes such interactions.' ' -Martyn Poliakoff, Green Chemistry, February ' Its is an introductory text taking a broad view and intergrating a wide range of topics including synthetic methodologies, alternative solvents and catalysts, biosynthesis and alternative feedstocks. There are exercises for students and the last chapter deals with future trends' Aslib

Phosphorus Compounds

Phosphorus Compounds
Author: Maurizio Peruzzini
Publisher: Springer Science & Business Media
Total Pages: 477
Release: 2011-06-10
Genre: Science
ISBN: 9048138175

Each chapter of Phosphorus Compounds: Advanced Tools in Catalysis and Material Sciences have been carefully selected by the editors in order to represent a state-of-the-art overview of how phosphorus chemistry can provide solutions in various fields of applications. The editors have assembled an international array of world-renowned scientists and each chapter is written by experts in the fields of synthetic chemistry, homogeneous catalysis, dendrimers, theoretical calculations, materials science, and medicinal chemistry with a special focus on the chemistry of phosphorus compounds. Phosphorus Compounds: Advanced Tools in Catalysis and Material Sciences is of interest to a general readership ranging from advanced university course students to experts in academia and industry.

How to Overcome the Antibiotic Crisis

How to Overcome the Antibiotic Crisis
Author: Marc Stadler
Publisher: Springer
Total Pages: 497
Release: 2016-12-21
Genre: Medical
ISBN: 3319492845

This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the “bad bugs” are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.

P-stereogenic Ligands in Enantioselective Catalysis

P-stereogenic Ligands in Enantioselective Catalysis
Author: Arnald Grabulosa
Publisher: Royal Society of Chemistry
Total Pages: 521
Release: 2011
Genre: Science
ISBN: 1849731233

P-stereogenic ligands were among the first to be used in asymmetric catalysis but synthetic difficulties and prejudices have hampered their development. However, continuous screening for new chiral ligands means that they can no longer be ignored and this rigorous reference source reflects their renaissance.The book is filled with many examples from recent primary literature. The synthetic chemist will easily be able to follow the preparation methods which are accompanied by a description of the challenges and limitations. Those working in homogenous catalysis, and wanting to increase their repertoire of ligands, will be able to establish which have already been used in each reaction and their performance.This book provides comprehensive coverage of the application of P-stereogenic ligands in homogeneous catalysis. It begins with a brief chapter on generalities of P-stereogenic compounds: history, configurational stability, and interconversions among them.The book then goes on to describe the main preparative methods, from resolution of racemates to enantioselective catalysis, before focusing on the catalytic applications of P-stereogenic ligands. Chapter 7 describes the use of the ligands in catalytic hydrogenation and related reactions whereas chapter 8 deals with other reactions, mainly C-C bond forming reactions. The aim of these two final chapters is to give an outline of the usefulness of the ligands in homogeneous catalysis.