Langerhans Cell Histiocytosis And Other Histiocytic Disorders
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| Author | : Oussama Abla |
| Publisher | : Springer |
| Total Pages | : 391 |
| Release | : 2017-11-17 |
| Genre | : Medical |
| ISBN | : 3319596322 |
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
| Author | : Rudolph Maarten Egeler |
| Publisher | : |
| Total Pages | : 213 |
| Release | : 1993 |
| Genre | : Histiocytosis |
| ISBN | : 9789090064055 |
| Author | : Sheila Weitzman |
| Publisher | : Cambridge University Press |
| Total Pages | : 0 |
| Release | : 2011-02-17 |
| Genre | : Medical |
| ISBN | : 9780521184168 |
This comprehensive reference on histiocytic disorders considers the genetics, pathophysiology, and clinical management of this wide range of diseases. It covers all aspects of hystiocytic disorders--from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis, to the uncommon cutaneous and extracutaneous histiocytic disorders. Current views on the function of normal histiocytes in the immune system, the pathogenesis, underlying genetic defects, clinical presentation, treatment, controversies in therapy, salvage therapies and the late consequences are also presented.
| Author | : Sheila Weitzman |
| Publisher | : Cambridge University Press |
| Total Pages | : 528 |
| Release | : 2011-02-17 |
| Genre | : Medical |
| ISBN | : 9781139444170 |
As a comprehensive reference on all aspects of the histiocytic disorders, Histiocytic Disorders of Children and Adults stands out a seminal text on the genetics, pathophysiology and clinical management of this wide range of diseases. The chapters, written by acknowledged experts in the field, cover all aspects of hystiocytic disorders, from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis, to the uncommon cutaneous and extracutaneous histiocytic disorders. Views on the function of normal histiocytes in the immune system, the pathogenesis, underlying genetic defects, clinical presentation, treatment, controversies in therapy, salvage therapies and the late consequences are discussed in detail. Originally published in 2005, this book will be a valuable resource to clinicians and researchers who wish to learn more about histiocytic disorders.
| Author | : Nishant Gupta |
| Publisher | : Springer Nature |
| Total Pages | : 384 |
| Release | : 2021-01-28 |
| Genre | : Medical |
| ISBN | : 3030633659 |
This book is a comprehensive reference on diffuse cystic lung diseases (DCLDs). DCLDs are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. In recent years, tremendous advancements have been made in these diseases leading to improved understanding of the underlying pathophysiology, and improved outcomes with targeted therapies. The authors, who are leading experts in the field, delineate DCLDs as a separate category distinct from other interstitial lung diseases, and have created this textbook specifically dedicated to this disease group. This book begins with a chapter introducing the definition and classification of DCLDs. Subsequent chapters address the pathogenic mechanisms underlying pulmonary cyst formation and provide a detailed overview of the radiological and pathological features of DCLDs. The common as well as uncommon causes of DCLDs are comprehensively reviewed in individual chapters, as are the varied clinical presentations and extrapulmonary manifestations, and approaches to management and treatment. The book culminates in a final chapter that presents a practical algorithmic approach to diagnosis that progresses from least invasive to most invasive approaches. This textbook provides a one-stop, comprehensive and integrated, clinical, radiologic, and pathologic overview of DCLDs that will be as useful to the practicing clinician as it is to the clinical investigator.
| Author | : Xiaoguang Cheng |
| Publisher | : Springer Nature |
| Total Pages | : 329 |
| Release | : 2021-03-11 |
| Genre | : Medical |
| ISBN | : 9813361506 |
This book provides a detailed description of typical imaging features of bone tumors and tumor-like lesions in the shoulder and elbow. Each chapter deals with one major bone tumor or tumor-like lesion, for example, giant cell tumor, bone cyst, osteochondroma, chondrosarcoma, Ewing sarcoma, bone metastases, lymphoma, etc. Typical cases are carefully selected from thousands of clinical cases accompanying with comprehensive imaging information of X-ray, CT and MRI. In-depth analysis and differential diagnostic tips from experienced bone tumor specialist are presented at the end of each case. This book will be useful and worthy to musculoskeletal radiologists, orthopaedic surgeons, general radiologists, and oncologists.
| Author | : Mani T. Valarmathi |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 152 |
| Release | : 2021-09-22 |
| Genre | : Medical |
| ISBN | : 1839629304 |
A rare disease is any disease or condition that affects a small percentage of the population. Many rare conditions are life-threatening or chronically debilitating, and unfortunately do not have appropriate treatments, rendering them incurable. In recent years, there has been substantial development in the area of rare disease research and its clinical applications, for instance, rare disease biology and genomics, epidemiology and preventions, early detection and screening, and diagnosis and treatment. In this context, this book consolidates the recent advances in rare disease biology and therapeutics, covering a wide spectrum of interrelated topics, and disseminates this essential knowledge in a comprehensible way to a greater scientific and clinical audience as well as patients, caregivers, and drug and device manufacturers, especially to support rare disease product development. Chapters cover such diseases as Felty’s syndrome, Löfgren’s syndrome, mesothelioma, epidermolysis bullosa, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 20 |
| Release | : 2012-01-09 |
| Genre | : Medical |
| ISBN | : 1464916985 |
Non-Langerhans-Cell Histiocytosis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Non-Langerhans-Cell Histiocytosis in a compact format. The editors have built Non-Langerhans-Cell Histiocytosis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Non-Langerhans-Cell Histiocytosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Non-Langerhans-Cell Histiocytosis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
| Author | : Michel R. Nasr |
| Publisher | : Springer |
| Total Pages | : 209 |
| Release | : 2019-03-23 |
| Genre | : Medical |
| ISBN | : 3030115151 |
Lymph node pathology is a complex and rapidly evolving field that requires integration of morphologic findings with a number of ancillary studies, as well as clinical information, to diagnose neoplastic and non-neoplastic hematopoietic disorders. Lymphomas are currently classified according to the 2016 Revision of the World Health Organization (WHO) Classification, which emphasizes, and for some diagnoses mandates, the integration of clinical information in diagnostic decision making. Successful collaboration and teamwork between pathology and clinical specialties (especially hematology/oncology) are paramount for excellent patient care. In addition to diagnosis, pathology plays a significant role in lymphoma prognostication and therefore contributes to patient’s management and follow-up. Lymph Node Pathology for Clinicians provides a concise overview of different entities in lymph node pathology with the primary audience being clinicians. Not all entities are covered, but, rather, the most common and/or clinically most relevant ones were included. This text is intended as a quick reference for a clinician to become familiar with pathologic aspects of lymphomas and the thought process of a pathologist. Particular consideration is given to relevant diagnostic and prognostic ancillary studies. Organized with an interdisciplinary approach for effective management of lymph node disorders, this text aims to educate our clinical colleagues on the most important aspects of lymph node pathology.
| Author | : Adekunle M. Adesina |
| Publisher | : Springer |
| Total Pages | : 327 |
| Release | : 2016-10-03 |
| Genre | : Medical |
| ISBN | : 3319334328 |
This text was created to fill a void in the practice of pediatric neuropathology. It is a practical and well-illustrated book representing a collection of interesting, common and unusual tumors for a diagnostic exercise by the reader. The wide reception of the first edition by the pathology community is testament to its relevance and utility in the pathologic diagnosis of pediatric brain tumors. This edition covers topics ranging from neuroimaging, the use of crush and touch preps during intraoperative consultation, classic histological features of pediatric brain tumors, tumor variants, and a miscellaneous group of challenging tumors. Chapters consist of essential diagnostic information and features highlighting recognized variants and their differential diagnoses. A section on molecular pathology and electron microscopy is also included for each tumor category, along with a list of classic reviews and innovative articles on each of the tumor entities as suggested reading at the end of each chapter. Atlas of Pediatric Brain Tumors, Second Edition represents the state of the art in pediatric neuropathology with easy utility beside the microscope.
