Culture of Animal Cells

Culture of Animal Cells
Author: R. Ian Freshney
Publisher: Wiley-Liss
Total Pages: 510
Release: 1993-12-29
Genre: Science
ISBN: 9780471589662

This masterful third edition of Freshney's Culture of Animal Cells updates and considerably expands the scope of its predecessor and still enables both the novice and the experiences researcher to apply the basic and more sophisticated techniques of tissue culture. New Topics covered include: the use of molecular techniques in cell culture, such as DNA fingerprinting, fluorescence in situ hybridization, and chromosome painting cell interactions in cell culture new methods for separating cells new or refined methods for accessing cytotoxicity, viability, and mutagenicity experimental details for culture of specialized cells types not covered in previous editions new or refined techniques for visualizing clues, including time-lapse photography and confocal microscopy The revised and expanded third edition offers the following features: over 350 new reference to the primary literature an international list of cell banks an international listing of reagants and commercial supplies a subject index a glossary Also available: 0471169021 Culture of Animal Cells: A Multimedia Guide CD-ROM $150 est. From the reviews: "I strongly recommend this volume for any laboratory wishing to culture mammalian cells" - Biotechnology "It is not very often that it is possible to say of a book, 'I don't know how I managed without it previously.' Here is such a book" - Cell Biology International Reports

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research
Author: National Research Council
Publisher: National Academies Press
Total Pages: 113
Release: 1988-02-01
Genre: Science
ISBN: 0309038391

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Management of Animal Care and Use Programs in Research, Education, and Testing

Management of Animal Care and Use Programs in Research, Education, and Testing
Author: Robert H. Weichbrod
Publisher: CRC Press
Total Pages: 917
Release: 2017-09-07
Genre: Medical
ISBN: 1498748457

AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals
Author: National Research Council
Publisher: National Academies Press
Total Pages: 246
Release: 2011-01-27
Genre: Science
ISBN: 0309154006

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Animal Cell Culture

Animal Cell Culture
Author: John M. Davis
Publisher: John Wiley & Sons
Total Pages: 389
Release: 2011-03-16
Genre: Science
ISBN: 0470975636

This is a comprehensive research guide that describes both the key new techniques and more established methods. Every chapter discusses the merits and limitations of the various approaches and then provides selected tried-and-tested protocols, as well as a plethora of good practical advice, for immediate use at the bench. It presents the most accessible and comprehensive introduction available to the culture and experimental manipulation of animal cells. Detailed protocols for a wide variety of methods provide the core of each chapter, making new methodology easily accessible. This book is an essential laboratory manual for all undergraduates and graduates about to embark on a cell culture project. It is a book which both experienced researchers and those new to the field will find invaluable.

Animal Cell Culture Techniques

Animal Cell Culture Techniques
Author: Martin Clynes
Publisher: Springer Science & Business Media
Total Pages: 624
Release: 2012-12-06
Genre: Science
ISBN: 3642804128

Cell culture techniques allow a variety of molecular and cell biological questions to be addressed, offering physiological conditions whilst avoiding the use of laboratory animals. In addition to basic techniques, a wide range of specialised practical protocols covering the following areas are included: cell proliferation and death, in-vitro models for cell differentiation, in-vitro models for toxicology and pharmacology, industrial application of animal cell culture, genetic manipulation and analysis of human and animal cells in culture.

Hearts and Minds

Hearts and Minds
Author: Julian McAllister Groves
Publisher: Temple University Press
Total Pages: 244
Release: 1997
Genre: Animal experimentation
ISBN: 9781439907696

Living in a university town that is a center of biomedical research, Groves found he could not ignore the intense opposition to research using animals. He began to analyze the formation and activities of local protest groups, attending meetings and talking to activists about their beliefs. To his surprise, many activists emphasized rational and scientific justifications for their commitment to the movement. Conversely, scientists frequently discussed their use of lab animals in the context of their attachment to pets or other animals and their concern for the environment. Groves seeks to understand these positions in connection with popular beliefs about the place of emotions in public life. Hearts and Minds looks past the placards and sound-bites to people's intellectual and psychological explanations for their positions. It discards worn generalizations and offers a nuanced portrait of people who are seriously engaged in reconciling their ethics and their behavior.

Animal Ethos

Animal Ethos
Author: Lesley A. Sharp
Publisher: University of California Press
Total Pages: 310
Release: 2018-11-06
Genre: Social Science
ISBN: 0520299256

What kinds of moral challenges arise from encounters between species in laboratory science? Animal Ethos draws on ethnographic engagement with academic labs in which experimental research involving nonhuman species provokes difficult questions involving life and death, scientific progress, and other competing quandaries. Whereas much has been written on core bioethical values that inform regulated behavior in labs, Lesley A. Sharp reveals the importance of attending to lab personnel’s quotidian and unscripted responses to animals. Animal Ethos exposes the rich—yet poorly understood—moral dimensions of daily lab life, where serendipitous, creative, and unorthodox responses are evidence of concerted efforts by researchers, animal technicians, veterinarians, and animal activists to transform animal laboratories into moral scientific worlds.

Laboratory Animal Welfare

Laboratory Animal Welfare
Author: Kathryn Bayne
Publisher: Academic Press
Total Pages: 335
Release: 2013-09-02
Genre: Medical
ISBN: 0123851041

Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.

Anthrax in Humans and Animals

Anthrax in Humans and Animals
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 219
Release: 2008
Genre: Business & Economics
ISBN: 9241547537

This fourth edition of the anthrax guidelines encompasses a systematic review of the extensive new scientific literature and relevant publications up to end 2007 including all the new information that emerged in the 3-4 years after the anthrax letter events. This updated edition provides information on the disease and its importance, its etiology and ecology, and offers guidance on the detection, diagnostic, epidemiology, disinfection and decontamination, treatment and prophylaxis procedures, as well as control and surveillance processes for anthrax in humans and animals. With two rounds of a rigorous peer-review process, it is a relevant source of information for the management of anthrax in humans and animals.