Biochemical Adaptation

Biochemical Adaptation
Author: Pater W. Hochachka
Publisher: Princeton University Press
Total Pages: 559
Release: 2014-07-14
Genre: Science
ISBN: 1400855411

This book discusses biochemical adaptation to environments from freezing polar oceans to boiling hot springs, and under hydrostatic pressures up to 1,000 times that at sea level. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

The Cell Theory

The Cell Theory
Author: John Randal Baker
Publisher: Facsimiles-Garl
Total Pages: 168
Release: 1988
Genre: Science
ISBN:

Protein Adaptation in Extremophiles

Protein Adaptation in Extremophiles
Author: Khawar Sohail Siddiqui
Publisher: Nova Publishers
Total Pages: 270
Release: 2008
Genre: Medical
ISBN: 9781604560190

Life has evolved in an extraordinary way to deal with the most extreme physical and chemical conditions. Extremophilic (extreme-loving) organisms have been found in the superheated waters of deep ocean vents or the hypersaline and cold lakes of Antarctica and indeed often require the extreme conditions of their habitat to survive and thrive. The cellular machinery of extremophiles has developed unique adaptation strategies to effectively function in their given environment. Much scientific attention has focussed on the adaptation of proteins as they have both structural and catalytic functions and hence play key roles in all cellular processes. Moreover, their ability to perform in or withstand extreme physical and chemical conditions has made extremophilic proteins attractive bio-catalysts for a range of industrial and biotechnological applications. This novel and significant book comprehensively summarises our current understanding regarding the structure-function-stability relationship of extremophilic proteins. Leading experts in the field extensively review and comment on the adaptation of proteins to the whole spectrum of physical and chemical extremes. This book represents an important and indispensable reference for students, teachers and researchers with interest or activities in the fascinating area of extremophiles.

The Lives of a Cell

The Lives of a Cell
Author: Lewis Thomas
Publisher: Penguin
Total Pages: 162
Release: 1978-02-23
Genre: Science
ISBN: 1101667052

Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us."

Ensuring the Integrity, Accessibility, and Stewardship of Research Data in the Digital Age

Ensuring the Integrity, Accessibility, and Stewardship of Research Data in the Digital Age
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 179
Release: 2009-11-17
Genre: Computers
ISBN: 0309147824

As digital technologies are expanding the power and reach of research, they are also raising complex issues. These include complications in ensuring the validity of research data; standards that do not keep pace with the high rate of innovation; restrictions on data sharing that reduce the ability of researchers to verify results and build on previous research; and huge increases in the amount of data being generated, creating severe challenges in preserving that data for long-term use. Ensuring the Integrity, Accessibility, and Stewardship of Research Data in the Digital Age examines the consequences of the changes affecting research data with respect to three issues - integrity, accessibility, and stewardship-and finds a need for a new approach to the design and the management of research projects. The report recommends that all researchers receive appropriate training in the management of research data, and calls on researchers to make all research data, methods, and other information underlying results publicly accessible in a timely manner. The book also sees the stewardship of research data as a critical long-term task for the research enterprise and its stakeholders. Individual researchers, research institutions, research sponsors, professional societies, and journals involved in scientific, engineering, and medical research will find this book an essential guide to the principles affecting research data in the digital age.

Physical Biology of the Cell

Physical Biology of the Cell
Author: Rob Phillips
Publisher: Garland Science
Total Pages: 1089
Release: 2012-10-29
Genre: Science
ISBN: 1134111584

Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that

Membrane Trafficking

Membrane Trafficking
Author: Ales Vancura
Publisher: Springer Science & Business Media
Total Pages: 430
Release: 2008-08-28
Genre: Science
ISBN: 9781588299253

As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.

The Sodium-Hydrogen Exchanger

The Sodium-Hydrogen Exchanger
Author: Morris Karmazyn
Publisher: Springer Science & Business Media
Total Pages: 356
Release: 2003-06-30
Genre: Science
ISBN: 9781402074745

I am extremely honored and pleased to have the opportunity to write a few introductory words for this timely volume on Na + /It exchange. This is a field of investigation that I entered into by challenge and necessity, embraced with passion and fmally left in my quest for new discoveries in growth control. Ten years, one third of my scientific life, has been devoted to uncovering the mysteries of intracellular pH (PH;) regulation with respect to growth factor action. I got started on this new topic in 1980, when I heard a rather provocative hypothesis presented by Enrique Rozengurt at an ICN-UCLA Keystone meeting on "Cell Surface and Malignancy". He showed that all mitogens induced amiloride-sensitive Na + entry into resting cells and proposed that, if a compound stimulates Na + influx, it could be a mitogen. In support of his proposal Enrique reported that the amphipathic polypeptide, mellitin, which induced Na+ influx, was indeed mitogenic for 3T3 cells. This was only correlation at this stage. However, I was fascinated by this talk. I immediately approached Enrique to inform him of my skepticism about this beautiful story, and to indicate that I would only be convinced when I succeeded in isolating mutant fibroblasts lacking the amiloride-sensitive Na+ transporter. ''Good luck!" was his response.