Introduction to the Thermodynamically Constrained Averaging Theory for Porous Medium Systems

Introduction to the Thermodynamically Constrained Averaging Theory for Porous Medium Systems
Author: William G. Gray
Publisher: Springer Science & Business Media
Total Pages: 609
Release: 2014-02-19
Genre: Science
ISBN: 3319040103

Thermodynamically constrained averaging theory provides a consistent method for upscaling conservation and thermodynamic equations for application in the study of porous medium systems. The method provides dynamic equations for phases, interfaces, and common curves that are closely based on insights from the entropy inequality. All larger scale variables in the equations are explicitly defined in terms of their microscale precursors, facilitating the determination of important parameters and macroscale state equations based on microscale experimental and computational analysis. The method requires that all assumptions that lead to a particular equation form be explicitly indicated, a restriction which is useful in ascertaining the range of applicability of a model as well as potential sources of error and opportunities to improve the analysis.

Introduction to Environmental Modeling

Introduction to Environmental Modeling
Author: William G. Gray
Publisher: Cambridge University Press
Total Pages: 449
Release: 2017
Genre: Science
ISBN: 1107571693

This textbook presents the timeless basic physical and mathematical principles and philosophy of environmental modeling to students who need to be taught how to think in a different way than they would for more narrowly-defined engineering or physics problems. Examples come from a range of hydrologic, atmospheric, and geophysical problems.

Quantitative Systems Pharmacology

Quantitative Systems Pharmacology
Author: Davide Manca
Publisher: Elsevier
Total Pages: 420
Release: 2018-07-18
Genre: Technology & Engineering
ISBN: 0444639675

Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource. - Outlines a model-based approach (based on Process Systems Engineering-OSE and Computer Aided Process Engineering-CAPE) in quantitative pharmacology - Explains how therapeutics work in the human body and how anatomy and physiology influences drug efficacy - Discusses how drugs are driven to specific targets using nanoparticles - Offers insight into how in vitro and in vivo experiments help understand the drug mechanism of action and optimize their performance - Includes case studies showing the positive outcome of these methods in personalized therapies, therapeutic drug monitoring, clinical trials analysis and drug formulation

Coupled Dynamics in Soil

Coupled Dynamics in Soil
Author: Yijian Zeng
Publisher: Springer Science & Business Media
Total Pages: 175
Release: 2012-12-14
Genre: Nature
ISBN: 3642340733

In arid and semi-arid areas, the main contributions to land surface processes are precipitation, surface evaporation and surface energy balancing. In the close-to-surface layer and root-zone layer, vapor flux is the dominant flux controlling these processes - process which, in turn, influence the local climate pattern and the local ecosystem. The work reported in this thesis attempts to understand how the soil airflow affects the vapor transport during evaporation processes, by using a two-phase heat and mass transfer model. The necessity of including the airflow mechanism in land surface process studies is discussed and highlighted.

Computational Modelling of Concrete Structures

Computational Modelling of Concrete Structures
Author: Günther Meschke
Publisher: CRC Press
Total Pages: 1034
Release: 2018-01-31
Genre: Technology & Engineering
ISBN: 1351726765

The EURO-C conference series (Split 1984, Zell am See 1990, Innsbruck 1994, Badgastein 1998, St. Johann im Pongau 2003, Mayrhofen 2006, Schladming 2010, St. Anton am Arlberg 2014, and Bad Hofgastein 2018) brings together researchers and practising engineers concerned with theoretical, algorithmic and validation aspects associated with computational simulations of concrete and concrete structures. Computational Modelling of Concrete Structures reviews and discusses research advancements and the applicability and robustness of methods and models for reliable analysis of complex concrete, reinforced concrete and pre-stressed concrete structures in engineering practice. The contributions cover both computational mechanics and computational modelling aspects of the analysis and design of concrete and concrete structures: Multi-scale cement and concrete research: experiments and modelling Aging concrete: from very early ages to decades-long durability Advances in material modelling of plain concrete Analysis of reinforced concrete structures Steel-concrete interaction, fibre-reinforced concrete, and masonry Dynamic behaviour: from seismic retrofit to impact simulation Computational Modelling of Concrete Structures is of special interest to academics and researchers in computational concrete mechanics, as well as industry experts in complex nonlinear simulations of concrete structures.

Handbook of Porous Media

Handbook of Porous Media
Author: Kambiz Vafai
Publisher: CRC Press
Total Pages: 946
Release: 2015-06-23
Genre: Science
ISBN: 1439885575

Handbook of Porous Media, Third Edition offers a comprehensive overview of the latest theories on flow, transport, and heat-exchange processes in porous media. It also details sophisticated porous media models which can be used to improve the accuracy of modeling in a variety of practical applications. Featuring contributions from leading experts i

Mathematical and Numerical Modeling in Porous Media

Mathematical and Numerical Modeling in Porous Media
Author: Martin A. Diaz Viera
Publisher: CRC Press
Total Pages: 372
Release: 2012-07-24
Genre: Mathematics
ISBN: 041566537X

Porous media are broadly found in nature and their study is of high relevance in our present lives. In geosciences porous media research is fundamental in applications to aquifers, mineral mines, contaminant transport, soil remediation, waste storage, oil recovery and geothermal energy deposits. Despite their importance, there is as yet no complete understanding of the physical processes involved in fluid flow and transport. This fact can be attributed to the complexity of the phenomena which include multicomponent fluids, multiphasic flow and rock-fluid interactions. Since its formulation in 1856, Darcy’s law has been generalized to describe multi-phase compressible fluid flow through anisotropic and heterogeneous porous and fractured rocks. Due to the scarcity of information, a high degree of uncertainty on the porous medium properties is commonly present. Contributions to the knowledge of modeling flow and transport, as well as to the characterization of porous media at field scale are of great relevance. This book addresses several of these issues, treated with a variety of methodologies grouped into four parts: I Fundamental concepts II Flow and transport III Statistical and stochastic characterization IV Waves The problems analyzed in this book cover diverse length scales that range from small rock samples to field-size porous formations. They belong to the most active areas of research in porous media with applications in geosciences developed by diverse authors. This book was written for a broad audience with a prior and basic knowledge of porous media. The book is addressed to a wide readership, and it will be useful not only as an authoritative textbook for undergraduate and graduate students but also as a reference source for professionals including geoscientists, hydrogeologists, geophysicists, engineers, applied mathematicians and others working on porous media.

Finite Volumes for Complex Applications VII-Elliptic, Parabolic and Hyperbolic Problems

Finite Volumes for Complex Applications VII-Elliptic, Parabolic and Hyperbolic Problems
Author: Jürgen Fuhrmann
Publisher: Springer
Total Pages: 499
Release: 2014-05-16
Genre: Mathematics
ISBN: 3319055917

The methods considered in the 7th conference on "Finite Volumes for Complex Applications" (Berlin, June 2014) have properties which offer distinct advantages for a number of applications. The second volume of the proceedings covers reviewed contributions reporting successful applications in the fields of fluid dynamics, magnetohydrodynamics, structural analysis, nuclear physics, semiconductor theory and other topics. The finite volume method in its various forms is a space discretization technique for partial differential equations based on the fundamental physical principle of conservation. Recent decades have brought significant success in the theoretical understanding of the method. Many finite volume methods preserve further qualitative or asymptotic properties, including maximum principles, dissipativity, monotone decay of free energy, and asymptotic stability. Due to these properties, finite volume methods belong to the wider class of compatible discretization methods, which preserve qualitative properties of continuous problems at the discrete level. This structural approach to the discretization of partial differential equations becomes particularly important for multiphysics and multiscale applications. Researchers, PhD and masters level students in numerical analysis, scientific computing and related fields such as partial differential equations will find this volume useful, as will engineers working in numerical modeling and simulations.

The Handbook of Groundwater Engineering, Third Edition

The Handbook of Groundwater Engineering, Third Edition
Author: John H. Cushman
Publisher: CRC Press
Total Pages: 1726
Release: 2016-11-25
Genre: Science
ISBN: 1315354535

This new edition adds several new chapters and is thoroughly updated to include data on new topics such as hydraulic fracturing, CO2 sequestration, sustainable groundwater management, and more. Providing a complete treatment of the theory and practice of groundwater engineering, this new handbook also presents a current and detailed review of how to model the flow of water and the transport of contaminants both in the unsaturated and saturated zones, covers the protection of groundwater, and the remediation of contaminated groundwater.

Advances in Chemical Engineering

Advances in Chemical Engineering
Author:
Publisher: Academic Press
Total Pages: 495
Release: 2008-09-22
Genre: Technology & Engineering
ISBN: 0080922929

The cross-fertilization of physico-chemical and mathematical ideas has a long historical tradition. This volume of Advances in Chemical Engineering is almost completely dedicated to a conference on "Mathematics in Chemical Kinetics and Engineering (MaCKiE-2007), which was held in Houston in February 2007, bringing together about 40 mathematicians, chemists, and chemical engineers from 10 countries to discuss the application and development of mathematical tools in their respective fields. - Updates and informs the reader on the latest research findings using original reviews - Written by leading industry experts and scholars - Reviews and analyzes developments in the field