Tests were conducted to define the various problems involved in the maintenance of an acceptable environment, the number of variables concerned with the man-machine concept, the operation, maintenance and evaluation of single units and integrated systems for the support of life in a simulated aerospace mission. The investigation covered primary problems and benefits associated with water recovery, personal hygiene, sanitation, nutrition, instrumentation, atmospheric conditions at various pressures and mixtures, clothing, crew accommodations, waste management and muscle-strength while confined in a chamber simulating an aerospace vehicle, and the facilities and support required to test and evaluate life support systems. (Author).