Insulin Action
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| Author | : Alan R. Saltiel |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 223 |
| Release | : 2007-10-05 |
| Genre | : Medical |
| ISBN | : 0387722041 |
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
| Author | : Ashok K. Srivastava |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 206 |
| Release | : 1998-05-31 |
| Genre | : Science |
| ISBN | : 9780792381136 |
In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.
| Author | : Sudhesh Kumar |
| Publisher | : John Wiley & Sons |
| Total Pages | : 624 |
| Release | : 2005-01-14 |
| Genre | : Medical |
| ISBN | : 9780470850084 |
Diabetes is now one of the major causes of morbidity worldwide. In many cases, the onset of diabetes is progressive, developing via a condition of insulin resistance. This book considers the development of this condition, its consequences and clinical and therapeutic aspects. The book reviews the normal biology of insulin action on glucose, lipids and proteins. It considers the pathological basis for insulin resistance in animal models and humans, and discusses the influence of heredity, dietary factors and exercise. Clinical consequences including dyslipidaemia, hypertension and polycystic ovary syndrome, and therapeutic strategies for treatment are also examined. * Provides an expert review of the phenomenon of insulin resistance * Brings together a host of recent research for the first time * Written by leading experts in biological and clinical research
| Author | : Ashok K. Srivastava |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 189 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 1461556473 |
In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.
| Author | : Richard I. G. Holt |
| Publisher | : John Wiley & Sons |
| Total Pages | : 1104 |
| Release | : 2017-03-06 |
| Genre | : Medical |
| ISBN | : 1118912020 |
Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world. The fifth edition features an array of brand new chapters, on topics including: Ischaemic Heart Disease Glucagon in Islet Regulation Microbiome and Diabetes Diabetes and Non-Alcoholic Fatty Liver Disease Diabetes and Cancer End of Life Care in Diabetes as well as a new section on Psychosocial aspects of diabetes. In addition, all existing chapters are fully revised with the very latest developments, including the most recent guidelines from the ADA, EASD, DUK and NICE. Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates Via the companion website, readers can access a host of additional online materials such as: 200 interactive MCQ's to allow readers to self-assess their clinical knowledge every figure from the book, available to download into presentations fully searchable chapter pdfs Once again, Textbook of Diabetes provides endocrinologists and diabetologists with a fresh, comprehensive and multi-media clinical resource to consult time and time again.
| Author | : Leonid Poretsky |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 788 |
| Release | : 2002 |
| Genre | : Diabetes |
| ISBN | : 9781402071140 |
Diabetes mellitus is a very common disease which affects approximately 150,000,000 worldwide. With its prevalence rising rapidly, diabetes continues to mystify and fascinate both practitioners and investigators by its elusive causes and multitude of This textbook is written for endocrinologists, specialists in other disciplines who treat diabetic patients, primary care physicians, housestaff and medical students. It covers, in a concise and clear manner, all aspects of the disease, from its pathogenesis on the molecular and cellular levels to its most modern therapy.
| Author | : Maurice Edward Krahl |
| Publisher | : |
| Total Pages | : 220 |
| Release | : 1961 |
| Genre | : Medical |
| ISBN | : |
| Author | : Gerald M. Reaven |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 388 |
| Release | : 1999-04 |
| Genre | : Medical |
| ISBN | : 9780896035881 |
In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.
| Author | : Derek LeRoith |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1606 |
| Release | : 2004 |
| Genre | : Medical |
| ISBN | : 9780781740975 |
Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.
| Author | : Francesc Posas |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 322 |
| Release | : 2008-01-24 |
| Genre | : Science |
| ISBN | : 3540755691 |
In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.
