Innovations in Supercritical Fluids

Innovations in Supercritical Fluids
Author: Keith W. Hutchenson
Publisher:
Total Pages: 488
Release: 1995
Genre: Science
ISBN:

Presents an overview of supercritical fluid science and technology with emphasis on developments in solubility and modeling. Provides comprehensive coverage of current research, including molecular interactions and simulations, phase behavior, chemical reactions in supercritical fluids, supercritical water oxidation, and forest products applications. Addresses various aspects of the supercritical water oxidation process, including fundamental kinetics and modeling, simulations of hydrogen bonding and solvation, catalysis, use of unconventional oxidants, corrosion issues, reactor design and simulation, and applications. Includes a new technique for the rapid and accurate mapping of critical curve phase boundaries.

Chemical Engineering Design

Chemical Engineering Design
Author: Gavin Towler
Publisher: Elsevier
Total Pages: 1321
Release: 2012-01-25
Genre: Technology & Engineering
ISBN: 0080966608

Chemical Engineering Design, Second Edition, deals with the application of chemical engineering principles to the design of chemical processes and equipment. Revised throughout, this edition has been specifically developed for the U.S. market. It provides the latest US codes and standards, including API, ASME and ISA design codes and ANSI standards. It contains new discussions of conceptual plant design, flowsheet development, and revamp design; extended coverage of capital cost estimation, process costing, and economics; and new chapters on equipment selection, reactor design, and solids handling processes. A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data, and Excel spreadsheet calculations, plus over 150 Patent References for downloading from the companion website. Extensive instructor resources, including 1170 lecture slides and a fully worked solutions manual are available to adopting instructors. This text is designed for chemical and biochemical engineering students (senior undergraduate year, plus appropriate for capstone design courses where taken, plus graduates) and lecturers/tutors, and professionals in industry (chemical process, biochemical, pharmaceutical, petrochemical sectors). New to this edition: - Revised organization into Part I: Process Design, and Part II: Plant Design. The broad themes of Part I are flowsheet development, economic analysis, safety and environmental impact and optimization. Part II contains chapters on equipment design and selection that can be used as supplements to a lecture course or as essential references for students or practicing engineers working on design projects. - New discussion of conceptual plant design, flowsheet development and revamp design - Significantly increased coverage of capital cost estimation, process costing and economics - New chapters on equipment selection, reactor design and solids handling processes - New sections on fermentation, adsorption, membrane separations, ion exchange and chromatography - Increased coverage of batch processing, food, pharmaceutical and biological processes - All equipment chapters in Part II revised and updated with current information - Updated throughout for latest US codes and standards, including API, ASME and ISA design codes and ANSI standards - Additional worked examples and homework problems - The most complete and up to date coverage of equipment selection - 108 realistic commercial design projects from diverse industries - A rigorous pedagogy assists learning, with detailed worked examples, end of chapter exercises, plus supporting data and Excel spreadsheet calculations plus over 150 Patent References, for downloading from the companion website - Extensive instructor resources: 1170 lecture slides plus fully worked solutions manual available to adopting instructors

Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture

Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture
Author: Gintaras V. Reklaitis
Publisher: John Wiley & Sons
Total Pages: 418
Release: 2017-10-09
Genre: Science
ISBN: 0470942371

Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product. The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry. Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scientists involved in product and process development, as well as teachers, on how to utilize QbD practices and applications effectively while complying with government regulations. The material is divided into three main sections: the first six chapters address the role of key technologies, including process modeling, process analytical technology, automated process control and statistical methodology in supporting QbD and establishing the associated design space. The second section consisting of seven chapters present a range of thoroughly developed case studies in which the tools and methodologies discussed in the first section are used to support specific drug substance and drug-product QbD related developments. The last section discussed the needs for integrated tools and reviews the status of information technology tools available for systematic data and knowledge management to support QbD and related activities. Highlights Demonstrates Quality by Design (QbD) concepts through concrete detailed industrial case studies involving of the use of best practices and assessment of regulatory implications Chapters are devoted to applications of QbD methodology in three main processing sectors—drug substance process development, oral drug product manufacture, parenteral product processing, and solid-liquid processing Reviews the spectrum of process model types and their relevance, the range of state-of-the-art real-time monitoring tools and chemometrics, and alternative automatic process control strategies and methods for both batch and continuous processes The role of the design space is demonstrated through specific examples and the importance of understanding the risk management aspects of design space definition is highlighted Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture is an ideal book for practitioners, researchers, and graduate students involved in the development, research, or studying of a new drug and its associated manufacturing process.

The Use of Dispersants in Marine Oil Spill Response

The Use of Dispersants in Marine Oil Spill Response
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 341
Release: 2020-04-24
Genre: Nature
ISBN: 0309478219

Whether the result of an oil well blowout, vessel collision or grounding, leaking pipeline, or other incident at sea, each marine oil spill will present unique circumstances and challenges. The oil type and properties, location, time of year, duration of spill, water depth, environmental conditions, affected biomes, potential human community impact, and available resources may vary significantly. Also, each spill may be governed by policy guidelines, such as those set forth in the National Response Plan, Regional Response Plans, or Area Contingency Plans. To respond effectively to the specific conditions presented during an oil spill, spill responders have used a variety of response optionsâ€"including mechanical recovery of oil using skimmers and booms, in situ burning of oil, monitored natural attenuation of oil, and dispersion of oil by chemical dispersants. Because each response method has advantages and disadvantages, it is important to understand specific scenarios where a net benefit may be achieved by using a particular tool or combination of tools. This report builds on two previous National Research Council reports on dispersant use to provide a current understanding of the state of science and to inform future marine oil spill response operations. The response to the 2010 Deepwater Horizon spill included an unprecedented use of dispersants via both surface application and subsea injection. The magnitude of the spill stimulated interest and funding for research on oil spill response, and dispersant use in particular. This study assesses the effects and efficacy of dispersants as an oil spill response tool and evaluates trade-offs associated with dispersant use.

Advanced Oxidation Processes for Water and Wastewater Treatment

Advanced Oxidation Processes for Water and Wastewater Treatment
Author: Simon Parsons
Publisher: IWA Publishing
Total Pages: 370
Release: 2004-03-01
Genre: Science
ISBN: 1843390175

The suitability of Advanced Oxidation Processes (AOPs) for pollutant degradation was recognised in the early 1970s and much research and development work has been undertaken to commercialise some of these processes. AOPs have shown great potential in treating pollutants at both low and high concentrations and have found applications as diverse as ground water treatment, municipal wastewater sludge destruction and VOCs control. Advanced Oxidation Processes for Water and Wastewater Treatment is an overview of the advanced oxidation processes currently used or proposed for the remediation of water, wastewater, odours and sludge. The book contains two opening chapters which present introductions to advanced oxidation processes and a background to UV photolysis, seven chapters focusing on individual advanced oxidation processes and, finally, three chapters concentrating on selected applications of advanced oxidation processes. Advanced Oxidation Processes for Water and Wastewater Treatment will be invaluable to readers interested in water and wastewater treatment processes, including professionals and suppliers, as well as students and academics studying in this area. Dr Simon Parsons is a Senior Lecturer in Water Sciences at Cranfield University with ten years' experience of industrial and academic research and development.

Sustainable Development of Algal Biofuels in the United States

Sustainable Development of Algal Biofuels in the United States
Author: National Research Council
Publisher: National Academies Press
Total Pages: 247
Release: 2013-01-18
Genre: Science
ISBN: 0309260329

Biofuels made from algae are gaining attention as a domestic source of renewable fuel. However, with current technologies, scaling up production of algal biofuels to meet even 5 percent of U.S. transportation fuel needs could create unsustainable demands for energy, water, and nutrient resources. Continued research and development could yield innovations to address these challenges, but determining if algal biofuel is a viable fuel alternative will involve comparing the environmental, economic and social impacts of algal biofuel production and use to those associated with petroleum-based fuels and other fuel sources. Sustainable Development of Algal Biofuels was produced at the request of the U.S. Department of Energy.

Industrial Environmental Chemistry

Industrial Environmental Chemistry
Author: Donald T. Sawyer
Publisher: Springer Science & Business Media
Total Pages: 310
Release: 2013-12-11
Genre: Science
ISBN: 1489923209

This monograph consists of manuscripts submitted by invited speakers who participated in the symposium "Industrial Environmental Chemistry: Waste Minimization in Industrial Processes and Remediation of Hazardous Waste," held March 24-26, 1992, at Texas A&M University. This meeting was the tenth annual international symposium sponsored by the Texas A&M Industry-University Cooperative Chemistry Program (IUCCP). The program was developed by an academic-industrial steering committee consisting of the co-chairmen, Professors Donald T. Sawyer and Arthur E. Martell of the Texas A&M University Chemistry Department, and members appointed by the sponsoring companies: Bernie A. Allen, Jr., Dow Chemical USA; Kirk W. Brown, Texas A&M University; Abraham Clearfield, Texas A&M University; Greg Leyes, Monsanto Company; Jay Warner, Hoechst-Celanese Corporation; Paul M. Zakriski, BF Goodrich Company; and Emile A. Schweikert, Texas A&M University (IUCCP Coordinator). The subject of this conference reflects the interest that has developed in academic institutions and industry for technological solutions to environmental contamination by industrial wastes. Progress is most likely with strategies that minimize waste production from industrial processes. Clearly the key to the protection and preservation of the environment will be through R&D that optimizes chemical processes to minimize or eliminate waste streams. Eleven of the papers are directed to waste minimization. An additional ten papers discuss chemical and biological remediation strategies for hazardous wastes that contaminate soils, sludges, and water.

Supercritical Fluid Technology for Drug Product Development

Supercritical Fluid Technology for Drug Product Development
Author: Peter York
Publisher: CRC Press
Total Pages: 815
Release: 2004-03-23
Genre: Medical
ISBN: 1135538174

Interconnecting the fundamentals of supercritical fluid (SCF) technologies, their current and anticipated utility in drug delivery, and process engineering advances from related methodological domains and pharmaceutical applications, this volume unlocks the potential of supercritical fluids to further the development of improved pharmaceutical prod

Innovative Wastewater Treatment & Resource Recovery Technologies: Impacts on Energy, Economy and Environment

Innovative Wastewater Treatment & Resource Recovery Technologies: Impacts on Energy, Economy and Environment
Author: Juan M. Lema
Publisher: IWA Publishing
Total Pages: 690
Release: 2017-06-15
Genre: Science
ISBN: 1780407866

This book introduces the 3R concept applied to wastewater treatment and resource recovery under a double perspective. Firstly, it deals with innovative technologies leading to: Reducing energy requirements, space and impacts; Reusing water and sludge of sufficient quality; and Recovering resources such as energy, nutrients, metals and chemicals, including biopolymers. Besides targeting effective C,N&P removal, other issues such as organic micropollutants, gases and odours emissions are considered. Most of the technologies analysed have been tested at pilot- or at full-scale. Tools and methods for their Economic, Environmental, Legal and Social impact assessment are described. The 3R concept is also applied to Innovative Processes design, considering different levels of innovation: Retrofitting, where novel units are included in more conventional processes; Re-Thinking, which implies a substantial flowsheet modification; and Re-Imagining, with completely new conceptions. Tools are presented for Modelling, Optimising and Selecting the most suitable plant layout for each particular scenario from a holistic technical, economic and environmental point of view.

Scaffolding In Tissue Engineering

Scaffolding In Tissue Engineering
Author: Peter X. Ma
Publisher: CRC Press
Total Pages: 656
Release: 2005-08-19
Genre: Medical
ISBN: 1420027565

The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.