Influence of the Host on Tumor Development

Influence of the Host on Tumor Development
Author: Ronald B. Herberman
Publisher: Springer Science & Business Media
Total Pages: 202
Release: 2012-12-06
Genre: Medical
ISBN: 9400925301

It is widely recognized that the host response to tumor munotherapy of experimental metastases in animal systems progression is an important determinant in cancer growth which are beginning to be developed for ultimate clinical and progression. Indeed, as indicated in Volume I of this trials of human cancer metastasis. series, the process of cancer growth and progression, leading This volume explores a variety of host properties that to tumor invasion and metastasis, is dependent upon the influence tumor development including dormancy, regress complex, dynamic interactions between the properties of the ion, and recurrence. In addition, current knowledge of the tumor as well as the properties of the host. While Volume III response of the central nervous system to cancer, cardiac of this series reviews in great detail the influence of tumor and pulmonary complications, dermatologic effects and development on the host, this volume emphasizes the in hematologic complications of malignancies is presented. fluence of the host on tumor development. These host re The endocrine and metabolic function of cancer patients, as sponses include host anti-tumor immune reactivity, tumor well as the production of hormones by tumors is also review dormancy, cachexia, multiple endocrine and paraneoplastic ed.

Comparative Oncology

Comparative Oncology
Author: Alecsandru Ioan Baba
Publisher:
Total Pages: 787
Release: 2007
Genre: Electronic books
ISBN: 9789732714577

Influence of Tumor Development on the Host

Influence of Tumor Development on the Host
Author: L.A. Liotta
Publisher: Springer Science & Business Media
Total Pages: 250
Release: 2012-12-06
Genre: Medical
ISBN: 940092528X

Recent experimental evidence has made it increasingly clear In particular, this volume reviews the discrete steps involved that the properties of invasive, malignant cells during tumor in metastatic invasion: the interaction of invasive tumor cells development substantially impact on the host. This is under with extracellular matrices, the basement membrane, attach scored by a variety of biochemical properties of tumor cells ment to extracellular matrices, local proteolytic degradation during their differentiation and metastatic dissemination. of matrices, and the locomotion of invasive tumor cells These properties can be analyzed at different stages of tumor through such areas of localized degradation. The critical growth and progression and this volume explores the role of the cell surface in secondary tumor formation is characteristics of primary tumors as well as the shared reviewed as are important advances in the molecular biology characteristics of both primary and secondary tumors. of metastasis initiation and maintenance. Recent advances The primary tumor comes into existence following in the role of DNA methylation in the generation of tumor preneoplastic biochemical and cellular events that ultimate cell heterogeneity and tumor progression are also critically ly result in malignant transformation. Various aspects of summarized. Chapters in this volume also review molecular metabolism, predetermined by nutritional status, often play aspects of metastatic progression, and the use of the tech a basic role. Obesity, for example, is cancer-promoting. Cell nologies of DNA transfection and somatic cell fusion in the surface carbohydrates, cytoskeletal proteins, glycoproteins, exploration of molecular aspects of metastatic progression.

Ecology and Evolution of Cancer

Ecology and Evolution of Cancer
Author: Beata Ujvari
Publisher: Academic Press
Total Pages: 292
Release: 2017-02-08
Genre: Medical
ISBN: 0128043806

Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. - Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine - Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors - Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems - Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies

Essentials of Glycobiology

Essentials of Glycobiology
Author: Ajit Varki
Publisher: CSHL Press
Total Pages: 694
Release: 1999
Genre: Medical
ISBN: 9780879696818

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Inflammation and Cancer

Inflammation and Cancer
Author: Bharat B. Aggarwal
Publisher: Springer
Total Pages: 489
Release: 2014-05-12
Genre: Medical
ISBN: 3034808372

This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.

Physics of Cancer

Physics of Cancer
Author: Claudia Mierke
Publisher: Iph001
Total Pages: 500
Release: 2018-10-24
Genre: Science
ISBN: 9780750317511

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

The Growth of Biological Thought

The Growth of Biological Thought
Author: Ernst Mayr
Publisher: Harvard University Press
Total Pages: 996
Release: 1982
Genre: Science
ISBN: 9780674364462

Explores the development of the ideas of evolutionary biology, particularly as affected by the increasing understanding of genetics and of the chemical basis of inheritance.

The Genetics of Cancer

The Genetics of Cancer
Author: B.A. Ponder
Publisher: Springer Science & Business Media
Total Pages: 222
Release: 2012-12-06
Genre: Medical
ISBN: 9401106770

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.