Immunology of ENT Disorders

Immunology of ENT Disorders
Author: Glenis K. Scadding
Publisher: Springer Science & Business Media
Total Pages: 236
Release: 2012-12-06
Genre: Medical
ISBN: 9401114366

Until recently, the contribution of immunological knowledge to the under standingand management ofENTdisorders was slight, being largely confined to the appreciation that many rhinitic patients were allergic. Happily, this situation is rapidly changing: the immunological basis of many disorders of the ears, nose and throat is becoming recognized and the mechanisms of the reactions involved are being elucidated. From this, rational therapy should evolve. This book aims to highlight some of the areas in which immunological mechanisms are involved in otorhinolaryngology. It is written by experts in their respective fields of immunology and allergy, otology, rhinology and pathology. It opens with an overview ofthe pathways ofthe immune response and the cells and molecules involved, leading to an appreciation of the normal defence mechanisms of the upper respiratory tract and possible areas offailure. There is then a chapter on HIV infection and how this may present to otorhinolaryngologists. The normal function of the tonsil and the immunological effects oftonsillectomy are then considered. The varying roles of fungi in ENT disorders ranging from commensal through allergen to invasive organisms is assessed by Professor R. J. Hay. Perhaps the most obvious immunological contribution to management thus far lies in the immunocytochemical diagnosis of pathological conditions of the ears, nose and throat and this is covered in a chapter by Professor Leslie Michaels.

Adamantiades-Behçet's Disease

Adamantiades-Behçet's Disease
Author: Christos Zouboulis
Publisher: Springer Science & Business Media
Total Pages: 612
Release: 2006-04-11
Genre: Medical
ISBN: 0306483823

It is with great pleasure that I write this Foreword to the Proceedings of the International Conference on Behçet’s Disease which was held in Berlin in June 2002. This was the first International Conference held under the auspices of the International Society for Behçet’s Disease which was founded in 2000 in Seoul. First, I congratulate our colleagues in Berlin, led by Professor Christos Zouboulis of the Department of Dermatology at the Free University of Berlin, for having organised a most successful conference and for having compiled these proceedings so rapidly. It will be realised immediately on scanning the contents of this book that the conference was truly international with 210 participants from 26 countries, as Professor Zouboulis has noted in his preface. These included basic scientists, epidemiologists, pathologists, clinicians and, importantly, representatives from patient organisations. The latter held their own conference alongside the scientific-medical conference to mutual benefit. The combined session of patients and doctors (abstracts on pp 601 – 626) gave the opportunity for an exchange of information and fruitful discussion. The wide ranging scope of the communications is evident from the index and it was most encouraging to see their origin – from all parts of the world, from senior and junior colleagues and, from many different disciplines. Many communications may be regarded as preliminary reports of research in progress and we look forward to seeing the definitive publications in appropriate journals in due course.

Interleukins in Cancer Biology

Interleukins in Cancer Biology
Author: Arseniy Yuzhalin
Publisher: Academic Press
Total Pages: 361
Release: 2014-06-27
Genre: Medical
ISBN: 0128013338

Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and remembering the most important facts. . - Summarizes and discusses existing facts on the impact of all known interleukins in occurrence, development, and progression of cancer - Categorizes and clarifies all interleukins based on their role in cancer - Contains comprehensive and exhaustive information on each molecule

Evidence-Based Clinical Practice in Otolaryngology

Evidence-Based Clinical Practice in Otolaryngology
Author: Luke Rudmik
Publisher: Elsevier Health Sciences
Total Pages: 203
Release: 2018-01-20
Genre: Medical
ISBN: 0323544614

Get a quick, expert overview of the many key facets of today's otolaryngology practice with this concise, practical resource. Dr. Luke Rudmik and a leading team of experts in the field address high-interest clinical topics in this fast-changing field. - Presents an evidence-based, clinical approach to leading topics in otolaryngology. - Covers key topics such as management of vertigo; management of adult sensorineural hearing loss; reflux in sinusitis; balloon catheter dilation in rhinology; epistaxis; functional rhinoplasty; sublingual immunotherapy for allergic rhinitis; pediatric obstructive sleep apnea; pediatric tonsillectomy; evaluation and management of unilateral vocal fold paralysis; management of hoarseness; endoscopic skull base resection for malignancy; management of glottic cancer; management of well-differentiated thyroid cancer; and management of the clinical node-negative neck in early stage oral cavity squamous cell carcinoma. - Consolidates today's available information and experience in this challenging area into one convenient resource.

Immunology of Renal Disease

Immunology of Renal Disease
Author: C.D. Pusey
Publisher: Springer Science & Business Media
Total Pages: 299
Release: 2012-12-06
Genre: Medical
ISBN: 9401139024

Although it has been appreciated for many years that immune processes underlie most types of glomerulonephritis, it is the recent explosion in knowl edge of cellular and molecular immunology that has prompted another book on the subject. The understanding of the mechanisms involved in renal injury requires the integration of information from in vitro cell-culture systems, experimental models of disease, and clinical studies. This volume draws on all of these sources in an attempt to explain current concepts of nephritis. Increased emphasis is placed on autoimmune processes, as opposed to the deposition of circulating immune complexes, although it will be apparent that these may overlap in the area of "in situ" immune complex formation. Of central importance in autoimmunity is the relationship between antigen pre senting cells (including B cells) expressing MHC class II molecules, autoan tigenic peptides, T helper lymphocytes, and various effector cells. The mechanisms by which the immune system may lead to tissue injury are also becoming better understood, and consideration is given to the role of inflam matory cells, the complement proteins, and soluble factors such as cytokines and eicosanoids.

Allergy and Immunotoxicology in Occupational Health

Allergy and Immunotoxicology in Occupational Health
Author: Takemi Otsuki
Publisher: Springer
Total Pages: 159
Release: 2016-10-12
Genre: Medical
ISBN: 9811003513

This book offers a collection of the latest clinical and research findings related to allergies, one of the most frequently treated conditions in occupational medicine. The chapters not only cover asthma but also elaborate on contact dermatitis, rhinitis, and other allergic conditions, providing readers with a comprehensive overview of the substances disrupting autoimmunity and their effects on the human body. Allergy and Immunotoxicology in Occupational Health is a valuable resource for professionals and researchers in the occupational health sector, who will discover novel insights into immune effects, providing a foundation for future considerations of the health impairments caused by environmental and occupational exposure to these substances.

Oxford Handbook of ENT and Head and Neck Surgery

Oxford Handbook of ENT and Head and Neck Surgery
Author: Rogan Corbridge
Publisher: OUP Oxford
Total Pages: 243
Release: 2009-12-24
Genre: Medical
ISBN: 0191039640

This second edition of a best-selling Oxford Medical Handbook provides a comprehensive guide to the practice of ENT and head and neck surgery in a concise, practical, and easily accessible format. For use on the ward or for revision purposes, this new edition is organised anatomically and each section provides a summary of the essential approach to a specific presenting complaint. Quick access chapters are included detailing emergency conditions and their acute management. This new edition includes expanded sections on anatomy, paediatrics, drugs, practical and surgical procedures, and emergencies. There are new chapters covering ENT manifestations in HIV/AIDS and sleep disorders. Still the only pocket-sized reference of ENT available, this handbook is unique in offering diagnostic flowcharts which guide readers based on specific sets of symptoms. Patient-centred and practical, this book represents a more accurate experience for those typically faced with ENT and head and neck surgery in clinical practice.

Immunological Aspects of Gastroenterology

Immunological Aspects of Gastroenterology
Author: Y.R. Mahida
Publisher: Springer Science & Business Media
Total Pages: 359
Release: 2012-12-06
Genre: Medical
ISBN: 940100790X

Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

Immunology of Liver Disease

Immunology of Liver Disease
Author: H.C. Thomas
Publisher: Springer Science & Business Media
Total Pages: 212
Release: 2012-12-06
Genre: Medical
ISBN: 9401114285

The role of the immune response in both the pathology of liver disease and in the modulation ofliver injury has been the subject of intense research. This book aims to present the current understanding of the involvement of the immune response in liver disease. The first chapters examine the role of the immune response in viral infections of the liver. These viruses cause hepatitis of varying severity and it is thought that many of the mechanisms responsible for liver cell injury are immunologically mediated. In addition three of these viruses, hepatitic B, C, and D, are associated with persistent infection and chronic liver disease. The role of the immune response in viral persistence is discussed. Further chapters are devoted to the three major autoimmune liver diseases which are thought to be the result of loss of tolerance to autologous liver tissue. There has been much recent research on cellular immune responses in these diseases but knowledge of the immunological processes which lead to the breakdown of tolerance and the mechanisms of tissue damage are limited. Other research has concentrated on the identification of the antigens which are the targets of this immune response. Linkage disequilibrium between MHC alleles and autoimmune diseases has suggested a role for immunogenetic factors.