Immune Memory and Vaccines: Great Debates

Immune Memory and Vaccines: Great Debates
Author: Shane Crotty
Publisher: Perspectives Cshl
Total Pages: 432
Release: 2018-01-31
Genre: Medical
ISBN: 9781621821540

"A subject collection from the Cold Spring Harbor perspectives in biology."

Ahead of the Curve

Ahead of the Curve
Author: Shane Crotty
Publisher: Univ of California Press
Total Pages: 303
Release: 2003-06
Genre: Biography & Autobiography
ISBN: 0520239040

A biography of one of America's most famous and important molecular biologists.

Immunization Safety Review

Immunization Safety Review
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 118
Release: 2003-11-26
Genre: Medical
ISBN: 0309168910

The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

The Panic Virus

The Panic Virus
Author: Seth Mnookin
Publisher: Simon and Schuster
Total Pages: 466
Release: 2012-01-03
Genre: Health & Fitness
ISBN: 1439158657

A searing account of how vaccine opponents have used the media to spread their message of panic, despite no scientific evidence to support them.

The Price We Pay

The Price We Pay
Author: Marty Makary
Publisher: Bloomsbury Publishing USA
Total Pages: 305
Release: 2019-09-10
Genre: Health & Fitness
ISBN: 1635574129

New York Times bestseller Business Book of the Year--Association of Business Journalists From the New York Times bestselling author comes an eye-opening, urgent look at America's broken health care system--and the people who are saving it--now with a new Afterword by the author. "A must-read for every American." --Steve Forbes, editor-in-chief, FORBES One in five Americans now has medical debt in collections and rising health care costs today threaten every small business in America. Dr. Makary, one of the nation's leading health care experts, travels across America and details why health care has become a bubble. Drawing from on-the-ground stories, his research, and his own experience, The Price We Pay paints a vivid picture of the business of medicine and its elusive money games in need of a serious shake-up. Dr. Makary shows how so much of health care spending goes to things that have nothing to do with health and what you can do about it. Dr. Makary challenges the medical establishment to remember medicine's noble heritage of caring for people when they are vulnerable. The Price We Pay offers a road map for everyday Americans and business leaders to get a better deal on their health care, and profiles the disruptors who are innovating medical care. The movement to restore medicine to its mission, Makary argues, is alive and well--a mission that can rebuild the public trust and save our country from the crushing cost of health care.

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research
Author: National Research Council
Publisher: National Academies Press
Total Pages: 113
Release: 1988-02-01
Genre: Science
ISBN: 0309038391

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Immunoproteomics

Immunoproteomics
Author: Kelly M. Fulton
Publisher: Humana
Total Pages: 0
Release: 2016-08-23
Genre: Medical
ISBN: 9781493963140

Providing current diverse approaches and techniques used to study the immunoproteome, Immunoproteomics: Methods and Protocols collects chapters from key researchers that deliver information to be used in diagnostics, disease progression, and vaccine correlates of protection analysis, to name but a few. This detailed volume includes techniques used for the study of the antibody targets of bacterial pathogens, viruses, and cancer, mass spectrometry-based approaches to characterize T-cell epitopes, chapters on detection and relative quantification of cytokines in serum, as well as in silico prediction of epitopes using sequence-based or modeling approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, Immunoproteomics: Methods and Protocols aids researchers in transferring these techniques to their own laboratories in addition to providing a reference to guide researchers toward appropriate techniques.

Micro- and Nanotechnology in Vaccine Development

Micro- and Nanotechnology in Vaccine Development
Author: Mariusz Skwarczynski
Publisher: William Andrew
Total Pages: 462
Release: 2016-09-20
Genre: Medical
ISBN: 0323400299

This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. - Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development - Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development - Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Values and Vaccine Refusal

Values and Vaccine Refusal
Author: Mark Navin
Publisher: Routledge
Total Pages: 250
Release: 2015-09-16
Genre: Philosophy
ISBN: 131765319X

Parents in the US and other societies are increasingly refusing to vaccinate their children, even though popular anti-vaccine myths – e.g. ‘vaccines cause autism’ – have been debunked. This book explains the epistemic and moral failures that lead some parents to refuse to vaccinate their children. First, some parents have good reasons not to defer to the expertise of physicians, and to rely instead upon their own judgments about how to care for their children. Unfortunately, epistemic self-reliance systematically distorts beliefs in areas of inquiry in which expertise is required (like vaccine immunology). Second, vaccine refusers and mainstream medical authorities are often committed to different values surrounding health and safety. For example, while vaccine advocates stress that vaccines have low rates of serious complications, vaccine refusers often resist vaccination because it is ‘unnatural’ and because they view vaccine-preventable diseases as a ‘natural’ part of childhood. Finally, parents who refuse vaccines rightly resist the utilitarian moral arguments – ‘for the greater good’ – that vaccine advocates sometimes make. Unfortunately, vaccine refusers also sometimes embrace a pernicious hyper-individualism that sanctions free-riding on herd immunity and that cultivates indifference to the interpersonal and social harms that unvaccinated persons may cause.