Human Cytomegalovirus
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Author | : Thomas E. Shenk |
Publisher | : Springer Science & Business Media |
Total Pages | : 477 |
Release | : 2008-05-09 |
Genre | : Medical |
ISBN | : 3540773495 |
This volume has gathered some of the experts in the field to review aspects of our understanding of CMV and to offer perspectives of the current problems associated with CMV. The editors and authors hope that the chapters will lead to a better understanding of the virus that will assist in the development of new and unique antivirals, a protective vaccine, and a full understanding of CMV's involvement in human disease.
Author | : Ann Arvin |
Publisher | : Cambridge University Press |
Total Pages | : 1325 |
Release | : 2007-08-16 |
Genre | : Medical |
ISBN | : 1139461648 |
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author | : Jennifer Louten |
Publisher | : Academic Press |
Total Pages | : 412 |
Release | : 2022-05-28 |
Genre | : Science |
ISBN | : 0323914926 |
Essential Human Virology, Second Edition focuses on the structure and classification of viruses, virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses and emerging and dangerous viruses. Additionally, how viruses cause disease (pathogenesis) is highlighted, along with discussions on immune response to viruses, vaccines, anti-viral drugs, gene therapy, the beneficial uses of viruses, research laboratory assays and viral diagnosis assays. Fully revised and updated with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses, the book provides students with a solid foundation in virology. - Focuses on human diseases and the cellular pathology that viruses cause - Highlights current and cutting-edge technology and associated issues - Presents real case studies and current news highlights in each chapter - Features dynamic illustrations, chapter assessment questions, key terms, and a summary of concepts, as well as an instructor website with lecture slides, a test bank and recommended activities - Updated and revised, with new chapters on coronaviruses, nonliving infectious agents, and notable non-human viruses
Author | : David W. Kimberlin |
Publisher | : |
Total Pages | : 1100 |
Release | : 2021-05-15 |
Genre | : |
ISBN | : 9781610025218 |
The AAP's authoritative guide on preventing, recognizing, and treating more than 200 childhood infectious diseases. Developed by the AAP's Committee on Infectious Diseases as well as the expertise of the CDC, the FDA, and hundreds of physician contributors.
Author | : Wang-Shick Ryu |
Publisher | : Academic Press |
Total Pages | : 441 |
Release | : 2016-03-30 |
Genre | : Science |
ISBN | : 0128009993 |
Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author's more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. - Presents viruses within their family structure - Contains recommended journal articles with perspectives to put primary literature in context - Includes integrated recommended reading references within each chapter - Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor's manual, study guide, and test bank
Author | : Felicity N.E. Gavins |
Publisher | : Academic Press |
Total Pages | : 254 |
Release | : 2015-10-31 |
Genre | : Medical |
ISBN | : 0128013257 |
Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 472 |
Release | : 2001-02-21 |
Genre | : Medical |
ISBN | : 0309174988 |
Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Author | : Paul D. Griffiths |
Publisher | : Createspace Independent Publishing Platform |
Total Pages | : 0 |
Release | : 2012 |
Genre | : Cytomegalovirus infections |
ISBN | : 9781477566794 |
Paul Griffiths, Professor of Virology at the Royal Free Hospital and University College London studied medicine at St Bartholomew's Hospital in London and has spent his professional life in medical virology. He has an international reputation, unrivalled expertise and insight into the effect that viruses can have on patients and their families. Professor Griffiths uses this experience and stories of real patients to demonstrate how cytomegalovirus has avoided detection and treatment for so long. He introduces you to CMV, an intelligent virus which evolved millions of years ago intending to infect everyone on the planet during childhood, spreading silently throughout the world whilst remaining unrecognised. Professor Griffiths explains how modern living has jolted this stealth virus out of its complacency, rapidly altering the conditions it needs to survive. Over a period of 100 years (a blink of the eye in evolutionary time) humans have changed their world to become cleaner, longer living life forms which avoid childhood infections, have babies later in life, swap organs during transplantation and even suppress their immune systems with drugs or HIV. Professor Griffiths describes how and why this virus has come out of obscurity to become a top target for elimination. Although you may never have heard its name, there is a good chance that you, your family and your friends have encountered it. After you have heard The Stealth Virus tell its own story, its victims are given a voice too. This book describes how CMV is being confronted and introduces the researchers who will defend us against its insidious and sometimes devastating consequences. This book brings medical virology to life. It is dedicated to those who have encountered The Stealth Virus and to those who have declared war upon it.
Author | : John E. Craighead |
Publisher | : Academic Press |
Total Pages | : 466 |
Release | : 2000-03-15 |
Genre | : Medical |
ISBN | : 0080538487 |
Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context of the pathogenic mechanisms involved. The author provides a comprehensive review of the older and contemporary literature, considering both the common and much rarer complications of infection. Pathology and Pathogenesis of Human Viral Disease is written from the unique perspective of the clinical pathologist. It will help clinicians and pathologists gain a better understanding of changes that occur in viral infected cells, tissues, and organs. It will also serve as a pathology source book for virologists, internists, and pediatricians. - Provides a comprehensive, worldwide perspective of viral disease pathology - Bridges the fields of pathology and virology; integrating clinical disease with cell and tissue pathology - Addresses topics from the perspective of the clinical pathologist - Illustrates unique, viral induced pathological lesions - Considers common and uncommon complications of infection
Author | : Ronald Ross Watson |
Publisher | : Academic Press |
Total Pages | : 430 |
Release | : 2019-01-10 |
Genre | : Science |
ISBN | : 012814467X |
Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development. - Provides information on agents that affect metabolism and other health-related conditions in the liver - Explores the impact of composition, including differences based on country of origin and processing techniques - Addresses the most positive results from dietary interventions using bioactive foods to impact liver disease, including reduction of inflammation and improved function