Horizons in Cancer Research. Volume 79

Horizons in Cancer Research. Volume 79
Author: Hiroto S. Watanabe
Publisher:
Total Pages: 0
Release: 2021-03-04
Genre: Medical
ISBN: 9781536193305

This compilation includes details about recent innovations in the field of cancer treatment as well as best practices for managing the disease in various forms. The first chapter deals with the potential anticancer properties of the plant Trigonella foenum-graecum, also known as fenugreek. Following this, the authors provide clinically relevant information on physical therapy for women with breast cancer as well as targeted therapy for metastatic triple-negative breast cancer. Then, the authors discuss the evolution of the field of systematic therapy for urothelial cancer, which ranges from chemotherapy to immune checkpoint inhibitor use. The final chapter highlights the chemo-preventive efficacy of phytochemicals in modulating the epigenetic mechanisms involved in the initiation and progression of cancer.

Topics in Anti-Cancer Research: Volume 10

Topics in Anti-Cancer Research: Volume 10
Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
Total Pages: 169
Release: 2021-12-13
Genre: Medical
ISBN: 981503930X

Topics in Anti-Cancer Research covers new developments in the field of cancer diagnosis and drug therapy. Novel drugs as anticancer agents include natural and synthetic phenazirines and other anti-cancer compounds. The series also covers information on the current understanding of the pathology and molecular biology of specific neoplasms. The diversity of research topics published in this book series give broad and valuable perspectives for cancer researchers, clinicians, cancer professionals aiming to develop novel anti-cancer targets and patents for the treatment of various cancers. The topics covered in this volume are: - Peptides can play a major role in combating cancer diseases - Studying of the CLL after treatment using fractal parameter of neoplastic lymphocytes detection (ΛNLD) - Mechanistic insight of rhenium-based compounds as anti- cancer agents - Targeting cancer-specific inflammatory components in cancer therapeutics - Marine natural products as a source of novel anticancer agents: a treasure from the ocean - PDX clinical trial design in anti-cancer research

Oxford Textbook of Oncology

Oxford Textbook of Oncology
Author: David J. Kerr
Publisher: Oxford University Press
Total Pages: 2837
Release: 2016-01-28
Genre: Medical
ISBN: 0191065110

Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

The Carbonic Anhydrases

The Carbonic Anhydrases
Author: W.R. Chegwidden
Publisher: Birkhäuser
Total Pages: 614
Release: 2013-11-11
Genre: Science
ISBN: 303488446X

Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene target studies. Since the early use of CA inhibitors as diuretics and in treating congestive heart failure, the enzyme has been target of considerable clinical attention. Much of this is now focused on endeavours to produce a new generation of such drugs for the effective treatment of glaucoma and other potential applications. Recent data, suggesting links between CA and various disease processes, including cancer, have stimulated further...

The Cancer Atlas

The Cancer Atlas
Author: Ahmedin Jemal
Publisher:
Total Pages: 0
Release: 2015
Genre: Cancer
ISBN: 9781604432282

This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.

New Research on Hematological Malignancies

New Research on Hematological Malignancies
Author: David K. Gioia
Publisher: Nova Science Publishers
Total Pages: 155
Release: 2021
Genre: Medical
ISBN: 9781536199895

"Hematological malignancies, defined as cancers that affect the blood, bone marrow, and lymph nodes, represent a serious health care challenge for oncologists. Chapter One focuses on cytogenetic and molecular markers and summarizes their importance in identification, treatment and prognosis in patients with myeloproliferative neoplasms. Chapter Two details the efficacy of treatment of myeloid hematologic malignancies with isocitrate dehydrogenase mutations by inhibitors of this enzyme. Chapter Three describes the use of Selinexor and other drugs for the treatment of hematologic malignancies. Chapter Four explains the utility of poly(ADP-ribose) polymerase inhibitors in the treatment of myelodysplastic syndrome and acute myeloid leukemia"--

Horizons in Cancer Research

Horizons in Cancer Research
Author: Hiroto S. Watanabe
Publisher:
Total Pages: 0
Release: 2021-12-31
Genre: Medical
ISBN: 9781685074326

This volume presents some of the latest research surrounding cancer. Chapter One provides a background on the importance of magnesium homeostasis, reviews the pre-clinical and clinical studies using magnesium therapy for cisplatin-induced acute kidney injury, and proposes future investigations to improve the translatability of these results to cancer treatment. Chapter Two discusses various liquid biomarkers of ovarian cancer such as exosomes, cell free DNA, miRNAs, circulating tumor cells, secretory proteins and autoantibodies and their subsequent detection via various nanobiosensors. Chapter Three explores the potential of mouse xenograft models for elucidating resistance mechanisms to cancer therapeutics. Chapter Four summarizes melatonin's beneficial effects in ovarian follicular cells and oocytes, followed by a comprehensive description of melatonin as an alternative treatment for ovarian cancer. Chapter Five deals with the gene signatures potentially implicated in the development of endometrial cancer. Lastly, Chapter Six updates current understanding of the role of glucocorticoid receptor-mediated actions in triple-negative breast cancer.