Histiocytic Disorders Of Children And Adults
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| Author | : Sheila Weitzman |
| Publisher | : Cambridge University Press |
| Total Pages | : 522 |
| Release | : 2011-02-17 |
| Genre | : Medical |
| ISBN | : 9781139444170 |
As a comprehensive reference on all aspects of the histiocytic disorders, Histiocytic Disorders of Children and Adults stands out a seminal text on the genetics, pathophysiology and clinical management of this wide range of diseases. The chapters, written by acknowledged experts in the field, cover all aspects of hystiocytic disorders, from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis, to the uncommon cutaneous and extracutaneous histiocytic disorders. Views on the function of normal histiocytes in the immune system, the pathogenesis, underlying genetic defects, clinical presentation, treatment, controversies in therapy, salvage therapies and the late consequences are discussed in detail. Originally published in 2005, this book will be a valuable resource to clinicians and researchers who wish to learn more about histiocytic disorders.
| Author | : Oussama Abla |
| Publisher | : Springer |
| Total Pages | : 391 |
| Release | : 2017-11-17 |
| Genre | : Medical |
| ISBN | : 3319596322 |
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
| Author | : Nishant Gupta |
| Publisher | : Springer Nature |
| Total Pages | : 384 |
| Release | : 2021-01-28 |
| Genre | : Medical |
| ISBN | : 3030633659 |
This book is a comprehensive reference on diffuse cystic lung diseases (DCLDs). DCLDs are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. In recent years, tremendous advancements have been made in these diseases leading to improved understanding of the underlying pathophysiology, and improved outcomes with targeted therapies. The authors, who are leading experts in the field, delineate DCLDs as a separate category distinct from other interstitial lung diseases, and have created this textbook specifically dedicated to this disease group. This book begins with a chapter introducing the definition and classification of DCLDs. Subsequent chapters address the pathogenic mechanisms underlying pulmonary cyst formation and provide a detailed overview of the radiological and pathological features of DCLDs. The common as well as uncommon causes of DCLDs are comprehensively reviewed in individual chapters, as are the varied clinical presentations and extrapulmonary manifestations, and approaches to management and treatment. The book culminates in a final chapter that presents a practical algorithmic approach to diagnosis that progresses from least invasive to most invasive approaches. This textbook provides a one-stop, comprehensive and integrated, clinical, radiologic, and pathologic overview of DCLDs that will be as useful to the practicing clinician as it is to the clinical investigator.
| Author | : Robert Wynn |
| Publisher | : Cambridge University Press |
| Total Pages | : 299 |
| Release | : 2017-02-16 |
| Genre | : Medical |
| ISBN | : 1107439361 |
A succinct summary of the key principles and facts that guide the everyday practice of modern, clinical paediatric hematology. Covering all the information necessary for examinations in the topic, this book is ideal for postgraduates studying paediatric hematology, as well as for junior doctors in training.
| Author | : Adekunle M. Adesina |
| Publisher | : Springer |
| Total Pages | : 327 |
| Release | : 2016-10-03 |
| Genre | : Medical |
| ISBN | : 3319334328 |
This text was created to fill a void in the practice of pediatric neuropathology. It is a practical and well-illustrated book representing a collection of interesting, common and unusual tumors for a diagnostic exercise by the reader. The wide reception of the first edition by the pathology community is testament to its relevance and utility in the pathologic diagnosis of pediatric brain tumors. This edition covers topics ranging from neuroimaging, the use of crush and touch preps during intraoperative consultation, classic histological features of pediatric brain tumors, tumor variants, and a miscellaneous group of challenging tumors. Chapters consist of essential diagnostic information and features highlighting recognized variants and their differential diagnoses. A section on molecular pathology and electron microscopy is also included for each tumor category, along with a list of classic reviews and innovative articles on each of the tumor entities as suggested reading at the end of each chapter. Atlas of Pediatric Brain Tumors, Second Edition represents the state of the art in pediatric neuropathology with easy utility beside the microscope.
| Author | : Bruce Smoller |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2021-10-07 |
| Genre | : Medical |
| ISBN | : 9783319538105 |
Bringing together thousands of the best dermatologic clinical and pathological photographs and figures from researchers and scientists around the world, this volume focuses on the most prevalent dermatologic disorders as they relate to cutaneous infectious and neoplastic conditions and procedural dermatology. It includes atypical presentations of various disorders, giving insight into differential diagnoses, helping to familiarize the reader with some of the rarest dermatologic disorders. Atlas of Dermatology, Dermatopathology and Venereology Volume 3 is written for dermatologists, dermatopathologists, and residents and summarizes data regarding any dermatologic disorder and syndrome. Each entry includes an introduction, clinical and pathological manifestations, diagnosis, differential diagnosis, and treatment and prognosis. div>/div/div/div
| Author | : S. David Hudnall |
| Publisher | : Springer |
| Total Pages | : 395 |
| Release | : 2019-08-02 |
| Genre | : Medical |
| ISBN | : 3030106306 |
This book is designed not as a comprehensive textbook, but instead as a short practical guide to diagnosis of neoplastic and non-neoplastic diseases of blood, bone marrow, and lymphoid tissues. Concise and easy to read, this text provides essential information in a bulleted text format. This simple format was chosen to provide essential information that may quickly be reviewed at the microscope. Each single-page entry begins with a brief one-line Snapshot description, followed by short descriptions of important clinical, morphologic, immunohistochemical, and genetic features, and ending with Caveats and Pearls and Differential Diagnosis. In most cases, entries are accompanied by a few high-quality histologic images. To keep the text concise, recommended texts and recent review articles are cited in the bibliography at the end of the book. To help quickly find alternative diagnoses, the index cross-references all differential diagnoses. The Pocket Guide to Diagnostic Hematopathology should be of use to practicing hematopathologists (academic and private) and hematologic oncologists, as well as trainees (fellows) in hematopathology and hematologic oncology.
| Author | : Robert O. Greer |
| Publisher | : Cambridge University Press |
| Total Pages | : 607 |
| Release | : 2017-07-06 |
| Genre | : Medical |
| ISBN | : 1316613992 |
A reference for tackling diagnostic dilemmas that pathologists and clinicians encounter when assessing pediatric head and neck disease.
| Author | : Michel R. Nasr |
| Publisher | : Springer |
| Total Pages | : 217 |
| Release | : 2019-03-23 |
| Genre | : Medical |
| ISBN | : 3030115151 |
Lymph node pathology is a complex and rapidly evolving field that requires integration of morphologic findings with a number of ancillary studies, as well as clinical information, to diagnose neoplastic and non-neoplastic hematopoietic disorders. Lymphomas are currently classified according to the 2016 Revision of the World Health Organization (WHO) Classification, which emphasizes, and for some diagnoses mandates, the integration of clinical information in diagnostic decision making. Successful collaboration and teamwork between pathology and clinical specialties (especially hematology/oncology) are paramount for excellent patient care. In addition to diagnosis, pathology plays a significant role in lymphoma prognostication and therefore contributes to patient’s management and follow-up. Lymph Node Pathology for Clinicians provides a concise overview of different entities in lymph node pathology with the primary audience being clinicians. Not all entities are covered, but, rather, the most common and/or clinically most relevant ones were included. This text is intended as a quick reference for a clinician to become familiar with pathologic aspects of lymphomas and the thought process of a pathologist. Particular consideration is given to relevant diagnostic and prognostic ancillary studies. Organized with an interdisciplinary approach for effective management of lymph node disorders, this text aims to educate our clinical colleagues on the most important aspects of lymph node pathology.
| Author | : Arthur Zimmermann |
| Publisher | : Springer |
| Total Pages | : 3517 |
| Release | : 2016-11-02 |
| Genre | : Medical |
| ISBN | : 9783319269559 |
This book covers all liver tumors and lesions that clinically and radiologically mimic liver tumors. It provides readers with a comprehensive overview of this complex and rapidly evolving field. All aspects of surgical pathology are addressed, supplemented by detailed presentations of the lesions’ cell-biologic and molecular features. In addition, the methods employed for diagnosis and diagnostic algorithms are discussed. It appeals to pathologists and hepatologists and serves as an invaluable aid to diagnosis.The field of liver tumors and tumor-like lesions in adults and children has experienced tremendous advances in recent years. Specifically, the recognition of novel entities, deepened insights into known tumors, and refinement of classifications have necessitated continual updates and reappraisals. In addition, previous understanding of hepatic carcinogenesis and tumor progression has been transformed by the very rapid evolution of our understanding of cell biology, genomics, signaling pathways, cell interactions, and mechanisms of invasion and spread of hepatic tumor cells. These general pathology issues must be combined with surgical pathology if a comprehensive understanding of liver tumor pathology is to be achieved.
