Helicobacter Pylori Protocols
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Author | : Christopher L. Clayton |
Publisher | : Springer Science & Business Media |
Total Pages | : 296 |
Release | : 1997-03-24 |
Genre | : Medical |
ISBN | : |
In Helicobacter pylori Protocols, leading experts bring together an outstanding collection state-of-the-art protocols for the identification and molecular manipulation of H. pylori. The authoritative contributors supply detailed and readily reproducible protocols for culturing H. pylori, for the isolation and restriction endonuclease digestion of H. pylori chromosomal DNA, and for the transformation and insertional mutagenesis of H. pylori. They also provide molecular epidemiological techniques, including ribotyping, PCR-RFLP, and RAPD-PCR. These procedures have been developed to solve the difficult technical problems created by the application of today's powerful bacterial genetic and molecular cloning techniques to H. pylori. Helicobacter pylori Protocols contains a wide variety of stand-alone techniques that are unfailingly reproducible. The book is certain to become a standard experimental and clinical laboratory reference for all those engaged in H. pylori work today.
Author | : T. Chiba |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 130 |
Release | : 2013-09-23 |
Genre | : Medical |
ISBN | : 3318024155 |
The discovery of proton pump inhibitors (PPIs) and their development over the years has dramatically changed the management of acid-related diseases. Today, the therapeutic domain of PPIs ranges from relief of symptoms to cure of mucosal lesions in the upper gastrointestinal tract. PPIs are among the most widely sold drugs in the world and are now even available as over-the-counter medication. This publication presents the experience of the last 25 years during which PPIs have become of enormous value in gastroenterology. The authors provide an update on a variety of subjects, starting with an introduction to the discovery and development of PPIs. This is followed by chapters on pharmacokinetics, pharmacodynamics and pharmacogenetics, gastroesophageal reflux disease, gastroprotection, Helicobacter pylori eradication treatment, peptic ulcer disease, functional dyspepsia, acid suppression in exocrine pancreatic insufficiency, and gastrointestinal and systemic side effects. Readers who are interested in a current overview of PPIs and their various applications will find this book of great value.
Author | : Shigeru Kamiya |
Publisher | : Springer Nature |
Total Pages | : 297 |
Release | : 2019-10-22 |
Genre | : Medical |
ISBN | : 303021916X |
This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.
Author | : Philip Sutton |
Publisher | : CABI |
Total Pages | : 316 |
Release | : 2010 |
Genre | : Medical |
ISBN | : 1845935942 |
This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.
Author | : David Hompes |
Publisher | : |
Total Pages | : 226 |
Release | : 2011 |
Genre | : Helicobacter pylori infections |
ISBN | : 9780956923004 |
Author | : Peter Malfertheiner |
Publisher | : Springer Science & Business Media |
Total Pages | : 479 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642753159 |
Helieobaeter pylori has recently been recognized as a new genus according to specific taxonomic criteria; the "popular" name Campylobaeter pylori has been corrected by scientific progress. Following the discovery of the spiral microorgan ism in gastric mucosa by Marshall and Warren in 1982, it took only a few years for H. pylori to become established as a factor in the pathogenesis of gastritis and peptic ulcer disease. Interest in different aspects of H. pylori has grown continuously and has attracted scientists from various medical and biological disciplines such as gastroenterology, microbiology, pathology, immunology, and pharmacology. Indeed H. pylori provides an excellent model for interdisciplinary interaction and cooperation. To promote this concept of interdisciplinary research and exchange of knowledge, a European Campylobacter (Helicobacter) Pylori Study Group was founded in 1987 in Copenhagen. The second meeting of this expanding group was held from October 12-14,1989 in Ulm, FRG. The fact that more than 500 participants attended the conference and that 187 original contributions from all five continents were presented clearly confirmed that H. pylori has "scientifically infected" the whole world. Our understanding of the microbiological and pathogenetic aspects of H. pylori is continuously being challenged as new results follow swifthy from different research areas. This book includes an update and progress report on the various aspects of H. pylori presented and discussed in special workshops held during the meeting in Ulm.
Author | : Robert Logan |
Publisher | : BMJ Books |
Total Pages | : 54 |
Release | : 2002-03-22 |
Genre | : Medical |
ISBN | : 9780727912664 |
This new ABC concentrating on major upper Gastrointestinal disorders reflects the latest advances in understanding of the pathophysiology and pathogenesis of upper GI diseases most of which now have precise diagnostic methods and relational and effective medical and surgical managements.
Author | : Nayoung Kim |
Publisher | : Springer |
Total Pages | : 532 |
Release | : 2016-06-16 |
Genre | : Medical |
ISBN | : 9812877061 |
This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.
Author | : Sinead M Smith |
Publisher | : Humana |
Total Pages | : 234 |
Release | : 2021-03-26 |
Genre | : Medical |
ISBN | : 9781071613016 |
This book brings together a collection of methods for the successful detection, culture and investigation of H. pylori, and its associated diseases. Chapters guide the reader through overviews on H. pylori infection, protocols for analyzing human clinical samples, and protocols for characterizing H. pylori, its functional components and its interactions with host cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Helicobacter pylori: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.
Author | : C. Scarpignato |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 481 |
Release | : 2004 |
Genre | : Medical |
ISBN | : 3805576587 |