Heightened Risk Of Cardiovascular Disease In Patients With Rheumatoid Arthritis
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| Author | : Udi Nussinovitch |
| Publisher | : Academic Press |
| Total Pages | : 768 |
| Release | : 2017-02-10 |
| Genre | : Medical |
| ISBN | : 0128032685 |
The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe. - A review of common, as well as unusual (yet clinically significant) medical cardiac complications of prevalent rheumatic, autoimmune and inflammatory diseases. - Focuses on aspects of pathophysiological processes, clinical presentations, screening tests, prognostic implications and novel therapeutic approaches. - Presents an up-to-date "level of evidence and "strengths of recommendations for suggested therapies and reviews all randomized clinical trials, meta-analyses and other supporting published clinical findings.
| Author | : Hani Almoallim |
| Publisher | : Springer Nature |
| Total Pages | : 562 |
| Release | : 2021-01-05 |
| Genre | : Medical |
| ISBN | : 9811583234 |
This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.
| Author | : Filippo Crea |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 263 |
| Release | : 2013-08-15 |
| Genre | : Medical |
| ISBN | : 8847053676 |
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
| Author | : Yasser El Miedany |
| Publisher | : Springer |
| Total Pages | : 439 |
| Release | : 2017-08-24 |
| Genre | : Medical |
| ISBN | : 3319599631 |
This book explores comorbidity in patients with rheumatic diseases and details both care and treatment options in standard clinical practice. Patients with rheumatic diseases are clinically complex, and the interplay of their disease activity with associated conditions may lead to increased morbidity and mortality. Recently there have been major advances in the management of rheumatic diseases, however, without addressing the potential comorbid conditions, including cardiovascular disease; pulmonary disease; and depression; outcomes remain poor. With its 19 chapters, covering the management of major rheumatic diseases (e.g. rheumatoid arthritis, systemic lupus erythematosus , and osteoarthritis), potential comorbidities and treatment recommendations, as well as possible interactions between conditions; this book addresses the gap between textbook medicine and day to day patients' care. Authors also discuss the new hot issue of the comorbidity index, comparing the standard tools to the recently developed indices and how they can assist the rheumatologists in determining disease burden, prognosis, and comorbidity probability. This book is an ideal clinical guide and reference that enables rheumatologists, internal medicine physicians, and residents to address the full clinical expression of these rheumatic diseases with views towards prevention or early management of comorbid conditions.
| Author | : Juan Carlos Kaski |
| Publisher | : |
| Total Pages | : 961 |
| Release | : 2019 |
| Genre | : Medical |
| ISBN | : 0198759932 |
The ESC Handbook on Cardiovascular Pharmacotherapy, based on the most recent guidelines in cardiovascular pharmacology, and containing a comprehensive A-Z formulary of common and less commonly used cardiac drugs and drug groups, provides practical and accessible guidance on all areas of drug prescribing.
| Author | : Dr. Scott Dougherty |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 364 |
| Release | : 2020-02-22 |
| Genre | : Medical |
| ISBN | : 0323754600 |
Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. - Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. - International editors and chapter authors ensure a truly global perspective. - Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. - Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. - Consolidates today's available information and guidance into a single, convenient resource.
| Author | : Ayman El-Baz |
| Publisher | : CRC Press |
| Total Pages | : 483 |
| Release | : 2011-08-23 |
| Genre | : Medical |
| ISBN | : 1439845573 |
Lung cancer remains the leading cause of cancer-related deaths worldwide. Early diagnosis can improve the effectiveness of treatment and increase a patient’s chances of survival. Thus, there is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because the current technology—namely, needle biopsy and bronchoscopy—fail to diagnose those cases. However, the analysis of small, indeterminate lung masses is fraught with many technical difficulties. Often patients must be followed for years with serial CT scans in order to establish a diagnosis, but inter-scan variability, slice selection artifacts, differences in degree of inspiration, and scan angles can make comparing serial scans unreliable. Lung Imaging and Computer Aided Diagnosis brings together researchers in pulmonary image analysis to present state-of-the-art image processing techniques for detecting and diagnosing lung cancer at an early stage. The book addresses variables and discrepancies in scans and proposes ways of evaluating small lung masses more consistently to allow for more accurate measurement of growth rates and analysis of shape and appearance of the detected lung nodules. Dealing with all aspects of image analysis of the data, this book examines: Lung segmentation Nodule segmentation Vessels segmentation Airways segmentation Lung registration Detection of lung nodules Diagnosis of detected lung nodules Shape and appearance analysis of lung nodules Contributors also explore the effective use of these methodologies for diagnosis and therapy in clinical applications. Arguably the first book of its kind to address and evaluate image-based diagnostic approaches for the early diagnosis of lung cancer, Lung Imaging and Computer Aided Diagnosis constitutes a valuable resource for biomedical engineers, researchers, and clinicians in lung disease imaging.
| Author | : W. Stephen Waring |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 160 |
| Release | : 2006-11-14 |
| Genre | : Medical |
| ISBN | : 0443101744 |
For many years, individual cardiovascular risk factors have been dealt with in isolation, often by specialists with an interest in one particular risk factor, for example hypertension or hypercholesterolaemia. There has recently been a move to emphasise the importance of reducing global cardiovascular risk, which requires clinicians to address any one of a number of different risk factors. The interplay between these various factors is important in our understanding of development of cardiovascular disease and, similarly, the synergistic effects of targeting different risk factors is important in risk reduction. This text provides a comprehensive and up-to-date review of modern cardiovascular risk management. It belongs to the 'In Clinical Practice' series, which incorporate multiple illustrations using novel and effective formats. Data are frequently presented as bullet point lists or tables so that the key information is clearly available. The emphasis is on overall cardiovascular risk reduction throughout, with integration of lifestyle and pharmacological interventions. Jointly written by specialists and GPs to provide cutting edge information tailored perfectly for the primary care settingInclude management algorithms to provide quick reference treatment pathwaysCredible evidence-based sources - when possible, evidence base for best practice by reference to primary research or international guidelinesBullet lists and short tables for clear presentation of key information
| Author | : Sven Plein |
| Publisher | : Springer |
| Total Pages | : 475 |
| Release | : 2015-09-15 |
| Genre | : Medical |
| ISBN | : 331920940X |
The book provides an introduction to CMR imaging that is understandable and focused on the relevant information needed to using CMR imaging in clinical practice. Cardiovascular magnetic resonance (CMR) imaging has become an established imaging modality with an expanding range of clinical indications. While in the past the availability of CMR imaging was limited to a few specialist centres the method is becoming more widely available. Most clinicians therefore need to have a general understanding of the diagnostic information that can be obtained from CMR imaging, the indications for referral as well as contraindications and limitations of the method. For cardiologists and radiologists in particular, CMR imaging will become a routine diagnostic tool and training curricula in Cardiology or Radiology reflect this trend by increasingly demanding training in CMR imaging.
| Author | : John H. Stone |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 489 |
| Release | : 2009-10-03 |
| Genre | : Medical |
| ISBN | : 1848009348 |
Important strides have been made in understanding the pathophysiologic basis of many inflammatory conditions in recent years, but rheumatology remains a discipline in which diagnosis is rooted in the medical history skillfully extracted from the patient, the careful physical examination, and the discriminating use of laboratory tests and imaging. Moreover, selection of the most appropriate therapy for patients with rheumatic diseases also remains heavily reliant upon clinical experience. Medical disciplines such as rheumatology that depend significantly upon clinical wisdom are prone to the development of systems of ‘Pearls’ and ‘Myths,’ related to the diseases they call their own, a ‘Pearl’ being a nugget of truth about the diagnosis or treatment of a particular disease that has been gained by dint of clinical experience and a ‘Myth’ being a commonly held belief that influences the practice of many clinicians – but is false. This book will pool together the clinical wisdom of seasoned, expert rheumatologists who participate in the care of patients with autoimmune diseases, systemic inflammatory disorders, and all other rheumatic conditions.
