Handbook Of Transcription Factor Nf Kappab
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Author | : Sankar Ghosh |
Publisher | : CRC Press |
Total Pages | : 246 |
Release | : 2006-10-20 |
Genre | : Medical |
ISBN | : 1420004271 |
Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov
Author | : Hsiou-Chi Liou |
Publisher | : Springer Science & Business Media |
Total Pages | : 202 |
Release | : 2007-02-26 |
Genre | : Science |
ISBN | : 0387335730 |
Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family.
Author | : Timothy R. Hughes |
Publisher | : Springer Science & Business Media |
Total Pages | : 310 |
Release | : 2011-05-10 |
Genre | : Medical |
ISBN | : 904819069X |
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
Author | : Guido Franzoso |
Publisher | : Humana |
Total Pages | : 359 |
Release | : 2021-07-09 |
Genre | : Medical |
ISBN | : 9781071616680 |
This detailed book serves as a systematic examination of the analytical methods to study the transcription factor NF-κB in physiology and disease. It provides an up-to-date guidebook to navigate both conventional and highly specialized methods to detect and analyze the different signaling pathways of NF-κB activation and contextualize them within organismal physiology and disease pathogenesis, using genetic and biochemical techniques and some of the most advanced computational and systems biology methods. Additionally, the volume includes several examples of approaches utilized by leading experts in the NF-κB field to analyze and modulate NF-κB signaling in specific physiological and disease contexts, along with some of the most promising approaches to pharmacologically target the NF-κB pathway in human disease. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, NF-κB Transcription Factors: Methods and Protocols is an up-to-date guide intended for both basic and translational scientists who are working in the dynamic NF-κB field.
Author | : Timothy R. Hughes |
Publisher | : Springer |
Total Pages | : 306 |
Release | : 2011-05-26 |
Genre | : Medical |
ISBN | : 9789048190706 |
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
Author | : Patrick Cramer |
Publisher | : |
Total Pages | : 226 |
Release | : 1997 |
Genre | : |
ISBN | : |
Author | : Manfred Gossen |
Publisher | : Springer Science & Business Media |
Total Pages | : 573 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642189326 |
With contributions by numerous experts
Author | : Michael Karin |
Publisher | : Springer |
Total Pages | : 268 |
Release | : 2011-05-06 |
Genre | : Medical |
ISBN | : 9783642160165 |
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology—from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
Author | : |
Publisher | : ScholarlyEditions |
Total Pages | : 359 |
Release | : 2012-12-26 |
Genre | : Medical |
ISBN | : 1464997101 |
Transcription Factors—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Transcription Factors. The editors have built Transcription Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Transcription Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Transcription Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author | : Vincent Bours |
Publisher | : |
Total Pages | : 247 |
Release | : 1993 |
Genre | : |
ISBN | : |