Gossypol

Gossypol
Author: Sheldon J. Segal
Publisher: Springer Science & Business Media
Total Pages: 268
Release: 2012-12-06
Genre: Medical
ISBN: 1461328098

The search for a reversible male contraceptive has centered upon the suppression of sperm production or sperm motility. Gossypol, a natural substance extracted from the cotton plant, appears to cause both of these effects. Its ability to reduce spermatogenesis in men is undeniable and has been demonstrated in both large studies in China and a smaller confirmatory study in Brazil. These investiga tions have revealed the remarkable fact that with gossypol, it is possible to separate an effect on the testis' gamete-producing function from an effect on its hormone-producing function. Thus, it is possible to maintain normal testosterone levels and libido while sperm counts (and motility) fall. Because of this unique and important action, gossypol warrants the fullest possible evaluation as a potential male contraceptive. Sheldon J. Segal vii ACKNOWLEDGMENT Lynn C. Landman played a major role in this publication by skillfully editing the manuscripts which were submitted for inclusion in this volume. Janet O'Connell added her efforts in editing, assembling texts and figures and handling final details required for publication. I thank these talented colleagues for their invaluable contributions.

Gossypol

Gossypol
Author: Sheldon J. Segal
Publisher: Springer
Total Pages: 296
Release: 1985
Genre: Health & Fitness
ISBN:

The search for a reversible male contraceptive has centered upon the suppression of sperm production or sperm motility. Gossypol, a natural substance extracted from the cotton plant, appears to cause both of these effects. Its ability to reduce spermatogenesis in men is undeniable and has been demonstrated in both large studies in China and a smaller confirmatory study in Brazil. These investiga tions have revealed the remarkable fact that with gossypol, it is possible to separate an effect on the testis' gamete-producing function from an effect on its hormone-producing function. Thus, it is possible to maintain normal testosterone levels and libido while sperm counts (and motility) fall. Because of this unique and important action, gossypol warrants the fullest possible evaluation as a potential male contraceptive. Sheldon J. Segal vii ACKNOWLEDGMENT Lynn C. Landman played a major role in this publication by skillfully editing the manuscripts which were submitted for inclusion in this volume. Janet O'Connell added her efforts in editing, assembling texts and figures and handling final details required for publication. I thank these talented colleagues for their invaluable contributions.

Toxic Constituents of Plant Foodstuffs

Toxic Constituents of Plant Foodstuffs
Author: Irvin Liener
Publisher: Elsevier
Total Pages: 517
Release: 2012-12-02
Genre: Technology & Engineering
ISBN: 0323147372

Toxic Constituents of Plant Foodstuffs focuses on toxic substances in foods of plant origin, including protease inhibitors, hemagglutinins, goitrogens, cyanogens, saponins, gossypol, lathyrogens, and allergens. The book also considers adventitious toxic factors in processed foods and miscellaneous toxic factors such as stimulants and depressants, hypoglycemic agents, toxic amino acids, metal-binding constituents, and hepatotoxins. This volume is organized into 13 chapters and begins with an overview of protease inhibitors, including their distribution in the plant kingdom, physical and chemical properties, and mechanism of interaction with proteases. The next chapters focus on the adventitious introduction of toxic factors into processed plant foods; the inactivation of the trypsin inhibitor and hemagglutinin found in legumes by cooking; and the extraction of a nontoxic, edible starch from cycads. The reader is also introduced to lathyrism, the toxicity of agglutinins, occurrence of goitrogens in thioglucoside-containing plants, and dietary sources of cyanogen. This book will be of interest and value to food scientists who are concerned with the safety of food supply and public health officials tasked with enforcing regulations necessary to ensure the safety of a particular food.

Handbook of Plant and Fungal Toxicants

Handbook of Plant and Fungal Toxicants
Author: J. P. Felix D'Mello
Publisher: CRC Press
Total Pages: 528
Release: 2020-03-27
Genre: Medical
ISBN: 100008339X

First published in 1997. Natural toxicants are the subject of research throughout the world, and they are used for many purposes. The Handbook of Plant and Fungal Toxicants presents a wide range of compounds and considers how they relate to food safety, therapeutic purposes in medicine, and uses in breeding plants for enhanced resistance to insects and disease. Alkaloids, both from plant and fungal sources, are emphasized. Also covered are a variety of toxicants and phytochemicals including: bracken fern poisons polyphenolics gossypol flavones isoflavones pyrimidine glycosides fruit and vegetable allergens linear furanocoumarins photosensitizing agents nitrates oxalates Pinus ponderosa toxicants The text stresses the positive aspects of plant secondary compounds and presents examples of beneficial attributes in the context of environmental protection and human health. An international authorship addresses the global diversity and ecological distribution of plant and fungal toxicants. This handbook is ideal for senior-level college students and post-graduate students studying animal science, toxicology, and pharmaceutical sciences.

Handbook of Plant and Fungal Toxicants

Handbook of Plant and Fungal Toxicants
Author: J. P. Felix D'Mello
Publisher: CRC Press
Total Pages: 369
Release: 2020-03-27
Genre: Medical
ISBN: 1000086887

First published in 1997. Natural toxicants are the subject of research throughout the world, and they are used for many purposes. The Handbook of Plant and Fungal Toxicants presents a wide range of compounds and considers how they relate to food safety, therapeutic purposes in medicine, and uses in breeding plants for enhanced resistance to insects and disease. Alkaloids, both from plant and fungal sources, are emphasized. Also covered are a variety of toxicants and phytochemicals including: bracken fern poisons polyphenolics gossypol flavones isoflavones pyrimidine glycosides fruit and vegetable allergens linear furanocoumarins photosensitizing agents nitrates oxalates Pinus ponderosa toxicants The text stresses the positive aspects of plant secondary compounds and presents examples of beneficial attributes in the context of environmental protection and human health. An international authorship addresses the global diversity and ecological distribution of plant and fungal toxicants. This handbook is ideal for senior-level college students and post-graduate students studying animal science, toxicology, and pharmaceutical sciences.

Veterinary Toxicology for Australia and New Zealand

Veterinary Toxicology for Australia and New Zealand
Author: Rosalind Dalefield
Publisher: Elsevier
Total Pages: 630
Release: 2017-06-23
Genre: Medical
ISBN: 0127999124

Veterinary Toxicology for Australia and New Zealand is a reference suited to the unique challenges of veterinary practice in Australia and New Zealand. Both streamlined and thorough in its coverage of poisons and treatments for those locations, this focused approach allows readers to quickly find relevant information that is presented in a concise and logical manner that is useful to clinicians. The authors draw upon a wealth of knowledge of the particularities of toxicology in Australia and New Zealand to present readers with the up-to-date information required to efficiently and effectively diagnose and treat their patients. Highlights toxins of specific concern in Australia and New Zealand Structures information in a logical way so that it can be located quickly Offers up-to-date information on current and emerging risks

Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy

Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy
Author: Benjamin Bonavida
Publisher: Springer Science & Business Media
Total Pages: 431
Release: 2008-07-31
Genre: Medical
ISBN: 1597454745

This book reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. It also introduces several current approaches developed by established investigators that are aimed at overcoming resistance. This is the first volume to compile studies on tumor cell sensitization. It will prove useful for students, scientists, clinicians and pharmaceutical companies.

Non-Traditional Feeds for Use in Swine Production (1992)

Non-Traditional Feeds for Use in Swine Production (1992)
Author: Phillip Thacker
Publisher: CRC Press
Total Pages: 745
Release: 2017-11-22
Genre: Nature
ISBN: 1351359789

Feed represents the single greatest expense associated with bringing pigs to market weight. Therefore, if you can reduce the cost of feeding without detriment to pig performance, the economics of swine production will improve. The ingredient list for swine rations has become fairly limited, and the majority of diets fed to pigs consist of a few staples, such as corn, wheat, barley, and soybean meal. Non-Traditional Feeds for Use in Swine Production explores over fifty non-traditional feedstuffs in terms of their nutritional content and their viability as alternative, cost effective food sources