Genomics and computational science for virus research

Genomics and computational science for virus research
Author: Hironori Sato
Publisher: Frontiers E-books
Total Pages: 183
Release:
Genre:
ISBN: 2889191265

A biologically striking and clinically important feature of viruses is their rapid evolutionary dynamics in nature. The continual interactions between viruses and host organisms promote quick changes in virus populations, eventually leading to co-evolution of viruses and hosts for their survival. The structural and functional information on the interactions between viruses and hosts should provide a molecular and biological basis to understand infection, replication, cell/host-tropism, immune escape, pathogenesis, and direction of evolution of viruses. The information is also essential to develop methods to control transmission and replication of pathogenic viruses. However, the integrated information on the structure, function, and evolution of viruses and hosts has remained poorly accumulated, partly due to the limitation of analytical methods. Recent progress in genome science and computational approach may open up a new avenue of research of the interactions between viruses and hosts by integrating information on the structures, functions, and evolution. In this Research Topic, we welcome papers concerning the computer-assisted structural and functional studies based on genomic information, with theoretical or in combination with experimental approaches, for understanding molecules, infection, replication, cell/host-tropism, immune escape, pathogenesis, and evolution of viruses in nature.

Virus Bioinformatics

Virus Bioinformatics
Author: Manja Marz
Publisher: MDPI
Total Pages: 330
Release: 2020-02-21
Genre: Science
ISBN: 3039218824

Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.

Introduction to Computational Genomics

Introduction to Computational Genomics
Author: Nello Cristianini
Publisher: Cambridge University Press
Total Pages: 200
Release: 2006-12-14
Genre: Computers
ISBN: 9780521856034

Where did SARS come from? Have we inherited genes from Neanderthals? How do plants use their internal clock? The genomic revolution in biology enables us to answer such questions. But the revolution would have been impossible without the support of powerful computational and statistical methods that enable us to exploit genomic data. Many universities are introducing courses to train the next generation of bioinformaticians: biologists fluent in mathematics and computer science, and data analysts familiar with biology. This readable and entertaining book, based on successful taught courses, provides a roadmap to navigate entry to this field. It guides the reader through key achievements of bioinformatics, using a hands-on approach. Statistical sequence analysis, sequence alignment, hidden Markov models, gene and motif finding and more, are introduced in a rigorous yet accessible way. A companion website provides the reader with Matlab-related software tools for reproducing the steps demonstrated in the book.

Impact of Advances in Computing and Communications Technologies on Chemical Science and Technology

Impact of Advances in Computing and Communications Technologies on Chemical Science and Technology
Author: National Research Council
Publisher: National Academies Press
Total Pages: 235
Release: 1999-08-31
Genre: Mathematics
ISBN: 0309184029

The Chemical Sciences Roundtable provides a forum for discussing chemically related issues affecting government, industry and government. The goal is to strengthen the chemical sciences by foster communication among all the important stakeholders. At a recent Roundtable meeting, information technology was identified as an issue of increasing importance to all sectors of the chemical enterprise. This book is the result of a workshop convened to explore this topic.

Encyclopedia of Bioinformatics and Computational Biology

Encyclopedia of Bioinformatics and Computational Biology
Author:
Publisher: Elsevier
Total Pages: 3421
Release: 2018-08-21
Genre: Medical
ISBN: 0128114320

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

The Art and Science of Analyzing Software Data

The Art and Science of Analyzing Software Data
Author: Christian Bird
Publisher: Elsevier
Total Pages: 673
Release: 2015-09-02
Genre: Computers
ISBN: 0124115438

The Art and Science of Analyzing Software Data provides valuable information on analysis techniques often used to derive insight from software data. This book shares best practices in the field generated by leading data scientists, collected from their experience training software engineering students and practitioners to master data science. The book covers topics such as the analysis of security data, code reviews, app stores, log files, and user telemetry, among others. It covers a wide variety of techniques such as co-change analysis, text analysis, topic analysis, and concept analysis, as well as advanced topics such as release planning and generation of source code comments. It includes stories from the trenches from expert data scientists illustrating how to apply data analysis in industry and open source, present results to stakeholders, and drive decisions. - Presents best practices, hints, and tips to analyze data and apply tools in data science projects - Presents research methods and case studies that have emerged over the past few years to further understanding of software data - Shares stories from the trenches of successful data science initiatives in industry

In Loeffler's Footsteps – Viral Genomics in the Era of High-Throughput Sequencing

In Loeffler's Footsteps – Viral Genomics in the Era of High-Throughput Sequencing
Author:
Publisher: Academic Press
Total Pages: 272
Release: 2017-10-20
Genre: Science
ISBN: 0128125993

In Loeffler's Footsteps – Viral Genomics in the Era of High-Throughput Sequencing, Volume 99, the latest in the Advances in Virus Research series, contains new information on the topic, with chapters covering Loeffler 4.0 – diagnostic metagenomics, Detection of a novel orthobunyavirus by metagenomic analysis – the situation after five years, New Squirrel and Rodent Viruses Detected by NGS, Astroviridae – A Growing Family, New Leaves in the Growing Pestivirus Tree, New BTV Serotypes and no End?, and The recently discovered Bokeloh Bat Lyssavirus - Evidence for its continued transmission in Europe. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. The series is a valuable resource for information on all topics of virus research, from bacteriophages to human viruses, with this volume focusing on genomics. - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field - Features a diverse range of virology topics

Artificial Intelligence and Computational Dynamics for Biomedical Research

Artificial Intelligence and Computational Dynamics for Biomedical Research
Author: Ankur Saxena
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 298
Release: 2022-11-07
Genre: Computers
ISBN: 3110762048

This work presents the latest development in the field of computational intelligence to advance Big Data and Cloud Computing concerning applications in medical diagnosis. As forum for academia and professionals it covers state-of-the-art research challenges and issues in the digital information & knowledge management and the concerns along with the solutions adopted in these fields.