Genetics And Oral Health
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| Author | : Alexandre Rezende Vieira |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2019-12-13 |
| Genre | : Medical |
| ISBN | : 9783030144845 |
This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patient’s condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.
| Author | : Alexandre Rezende Vieira |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 165 |
| Release | : 2022-01-25 |
| Genre | : Medical |
| ISBN | : 3318069132 |
Individual susceptibility to disease (i.e., one’s own genetic background) is one of the three main components classically described in the etiology of dental caries. Hence, genes influence susceptibility to erosive tooth wear, dental development, and response to treatments and interventions. This publication is an up-to-date overview of individual susceptibility to dental caries, erosive tooth wear, and disturbances of dental development from different clinically relevant perspectives. One of the most recognized scientists in this field reports on recent research relating to human genetics – from general summaries to recommendations for daily clinical work and population-level interventions. This book covers all aspects of individual susceptibility to dental caries and erosive tooth wear. Several chapters deal with potential biological mechanisms, with additional ones providing a strong foundation in human genetics, and other chapters touch on efficacy of therapies and alternative concepts. This book is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on dental caries and erosive tooth wear.
| Author | : Dr Harisha Dewan |
| Publisher | : DENTOMED PUBLICATION HOUSE |
| Total Pages | : 115 |
| Release | : 2021-05-29 |
| Genre | : Medical |
| ISBN | : 8195032885 |
This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing.
| Author | : Ole Fejerskov |
| Publisher | : John Wiley & Sons |
| Total Pages | : 641 |
| Release | : 2009-03-16 |
| Genre | : Medical |
| ISBN | : 1444309285 |
The second edition of Dental Caries: the Disease and its Clinical Management builds on the success of the prestigious first edition to present an unrivaled resource on cariology. The clinical thrust of the first edition is widened and strengthened to include coverage of the disease in all its variety, from eruption of the first primary tooth to the prevalent forms of the disease in older patients. The centrality of caries control and management to the dental health of all populations is further emphasized, as the book goes beyond the successful treatment of carious lesions to demonstrate the long-term consequences of the non-operative and therapeutic techniques employed.
| Author | : Agnes Bloch-Zupan |
| Publisher | : Elsevier |
| Total Pages | : 265 |
| Release | : 2012-03-21 |
| Genre | : Medical |
| ISBN | : 0124160387 |
Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. Comprehensive examination of dento/oro/craniofacial anomalies Well-illustrated examples Presented in a compact, easy to use format
| Author | : Shuai Li |
| Publisher | : Academic Press |
| Total Pages | : 376 |
| Release | : 2021-08-19 |
| Genre | : Medical |
| ISBN | : 0128209526 |
Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. - Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties - Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders - Features chapter contributions from a wide range of international researchers in the field
| Author | : Grant C Townsend |
| Publisher | : University of Adelaide Press |
| Total Pages | : 218 |
| Release | : 2015-10-08 |
| Genre | : Health & Fitness |
| ISBN | : 1925261158 |
This volume is about an ongoing long-term research initiative led by researchers from the School of Dentistry at the University of Adelaide. The aim of this book is to provide an overview of the studies of the teeth and faces of Australian twins and their families that have extended over more than thirty years.
| Author | : Lester William Burket |
| Publisher | : B.C. Decker |
| Total Pages | : 680 |
| Release | : 2003 |
| Genre | : Medical |
| ISBN | : |
Presenting the status of the fields of oral medicine and clinical oral pathology, this text also outlines the dentist's role in the management of patients with severe medical problems. It reflects the dramatic alterations in some disease patterns as well as the medical advances, which have made an impact on the field of oral medicine. Focusing on knowledge of the pathogenesis and management of diseases, it stresses new diagnostic techniques as well as new concepts of therapy. Chapter topics include the significant research in the field of facial pain management and the impact in oral medicine of such diseases as asthma, chronic obstructive pulmonary disease and tuberculosis. Also examined is the growing importance of geriatrics in dentistry and the issues of Alzheimer's, Parkinson's disease and elderly patients receiving multiple medications. The book includes a CD-ROM with complete text and illustrations.
| Author | : Stephen T. Sonis |
| Publisher | : Academic Press |
| Total Pages | : 460 |
| Release | : 2019-09-14 |
| Genre | : Medical |
| ISBN | : 0128137630 |
Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. - Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine - Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases - Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader - Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care
| Author | : Emmanuel Lesaffre |
| Publisher | : John Wiley & Sons |
| Total Pages | : 408 |
| Release | : 2009-03-09 |
| Genre | : Mathematics |
| ISBN | : 9780470744123 |
Statistical and Methodological Aspects of Oral Health Research provides oral health researchers with an overview of the methodological aspects that are important in planning, conducting and analyzing their research projects whilst also providing biostatisticians with an idea of the statistical problems that arise when tackling oral health research questions. This collection presents critical reflections on oral health research and offers advice on practical aspects of setting up research whilst introducing the reader to basic as well as advanced statistical methodology. Features: An introduction to research methodology and an exposition of the state of the art. A variety of examples from oral health research. Contributions from well-known oral health researchers, epidemiologists and biostatisticians, all of whom have rich experience in this area. Recent developments in statistical methodology prompted by a variety of dental applications. Presenting both an introduction to research methodology and an exposition of the latest advances in oral health research, this book will appeal both beginning and experienced oral health researchers as well as biostatisticians and epidemiologists.
