Genetic Engineering Shaping The Material Of Life
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| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 607 |
| Release | : 2017-01-28 |
| Genre | : Science |
| ISBN | : 0309437385 |
Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 329 |
| Release | : 2017-08-13 |
| Genre | : Medical |
| ISBN | : 0309452880 |
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
| Author | : |
| Publisher | : North Carolina State University Libraries |
| Total Pages | : 0 |
| Release | : 2019 |
| Genre | : Art |
| ISBN | : 9781469659268 |
Evolution has gotten us this far. Design may take it from here. Aimed at raising awareness about genetic engineering, biotechnologies, and their consequences through the lens of art and design, Art's Work in the Age of Biotechnology: Shaping Our Genetic Futures is an art-science exhibition curated by Hannah Star Rogers and organized by the NC State University Libraries and the Genetic Engineering and Society Center, and shown at the Gregg Museum of Art & Design, in the physical and digital display spaces of the Libraries, and on the grounds of the North Carolina Museum of Art. By combining science and art and design, artists offer new insights about genetic engineering by bringing it out of the lab and into public places to challenge viewers' understandings about the human condition, the material of our bodies, and the consequences of biotechnology. Exhibition participants include Kirsten Stolle, Paul Vanouse, Adam Zaretsky, Joe Davis, Emilia Tikka, Emeka Ikebude, Jennifer Willet, Charlotte Jarvis, Maria McKinney, Ciara Redmond, Aaron Ellison, David Buckley Borden, Joel Ong, and others.
| Author | : The Royal Society |
| Publisher | : National Academies Press |
| Total Pages | : 239 |
| Release | : 2021-01-16 |
| Genre | : Medical |
| ISBN | : 0309671132 |
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
| Author | : Ellen Thro |
| Publisher | : |
| Total Pages | : 121 |
| Release | : 1993-01 |
| Genre | : Juvenile Nonfiction |
| ISBN | : 9780816026296 |
Defines and traces the history of genetic engineering and describes its uses in medicine, agriculture, and business.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 158 |
| Release | : 2015-06-29 |
| Genre | : Science |
| ISBN | : 0309316553 |
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
| Author | : Bruce R. Korf |
| Publisher | : John Wiley & Sons |
| Total Pages | : 280 |
| Release | : 2012-11-19 |
| Genre | : Medical |
| ISBN | : 1118537661 |
This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice 'Hot topics' boxes that focus on the latest developments in testing, assessment and treatment 'Ethical issues' boxes to prompt further thought and discussion on the implications of genetic developments 'Sources of information' boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.
| Author | : Desmond S. T. Nicholl |
| Publisher | : Cambridge University Press |
| Total Pages | : 308 |
| Release | : 2002-02-07 |
| Genre | : Medical |
| ISBN | : 9780521004718 |
The author presents a basic introduction to the world of genetic engineering. Copyright © Libri GmbH. All rights reserved.
| Author | : Luis A. Campos |
| Publisher | : University of Chicago Press |
| Total Pages | : 317 |
| Release | : 2021-07-16 |
| Genre | : Science |
| ISBN | : 022678357X |
“Engineering” has firmly taken root in the entangled bank of biology even as proposals to remake the living world have sent tendrils in every direction, and at every scale. Nature Remade explores these complex prospects from a resolutely historical approach, tracing cases across the decades of the long twentieth century. These essays span the many levels at which life has been engineered: molecule, cell, organism, population, ecosystem, and planet. From the cloning of agricultural crops and the artificial feeding of silkworms to biomimicry, genetic engineering, and terraforming, Nature Remade affirms the centrality of engineering in its various forms for understanding and imagining modern life. Organized around three themes—control and reproduction, knowing as making, and envisioning—the chapters in Nature Remade chart different means, scales, and consequences of intervening and reimagining nature.
| Author | : Susan Wright |
| Publisher | : University of Chicago Press |
| Total Pages | : 615 |
| Release | : 1994-10-17 |
| Genre | : Health & Fitness |
| ISBN | : 0226910660 |
The promise of genetic engineering in the early 1970s to profoundly reshape the living world activated a variety of social interests in its future promotion and control. With public safety, gene patents, and the future of genetic research at stake, a wide range of interest groups competed for control over this powerful new technology. In this comparative study of the development of regulatory policy for genetic engineering in the United States and the United Kingdom, Susan Wright analyzes government responses to the struggles among corporations, scientists, universities, trade unions, and public interest groups over regulating this new field. Drawing on archival materials, government records, and interviews with industry executives, politicians, scientists, trade unionists, and others on both sides of the Atlantic, Molecular Politics provides a comprehensive account of a crucial set of policy decisions and explores their implications for the political economy of science. By combining methods from political science and the history of science, Wright advances a provocative interpretation of the evolution of genetic engineering policy and makes a major contribution to science and public policy studies.
