This report, commissioned by the U.S. government in response to a growing public health crisis, provides a comprehensive overview of pellagra, a disease caused by niacin deficiency that was epidemic in the American South during the early twentieth century. The report includes detailed information on the symptoms, diagnosis, and treatment of the disease, as well as recommendations for public health interventions to address the crisis. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.