Gastric Cytoprotection Experimental And Clinical Studies
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Author | : Helmut Sinzinger |
Publisher | : Springer Science & Business Media |
Total Pages | : 480 |
Release | : 1997 |
Genre | : Medical |
ISBN | : 9780306457760 |
One hundred papers treat advances in research of the effects and uses of prostaglandins, thromboxanes, and leukotrienes in such medical fields as organ transplantation, male erectile dysfunction, amniotic fluid infection and labour, renal function, anti-inflammatory drugs, allergic and aspirin-intolerant asthma, angioplasty and heart ischemia, Alzheimer's disease, vessel wall hyperplasia, and more. Annotation copyrighted by Book News, Inc., Portland, OR
Author | : Rodolfo Cheli |
Publisher | : |
Total Pages | : 320 |
Release | : 1988 |
Genre | : Medical |
ISBN | : |
Author | : Daniel Hollander |
Publisher | : Springer Science & Business Media |
Total Pages | : 228 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1468456970 |
Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal mucosa is normally protected by a complex series of events includ ing mucus and bicarbonate secretion, cell renewal, surface mucosal restitution, and preservation of the microvasculature and mucosal proliferative zone.
Author | : |
Publisher | : |
Total Pages | : 382 |
Release | : 1990 |
Genre | : Drugs |
ISBN | : |
Author | : L.P. Filaretova |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 259 |
Release | : 2012-06-22 |
Genre | : Medical |
ISBN | : 3318021849 |
In recent years, there have been significant advances both in understanding the mechanisms involved in gastrointestinal mucosal injury and protection, as well as in the development of successful strategies for prevention and treatment of gastrointestinal injury. Nevertheless, many people worldwide still suffer from gastrointestinal damage.This book contains contributions by an international panel of researchers in the form of up-to-date reviews on the mechanisms of gastrointestinal injury and protection. These are complemented by papers discussing how these new findings about cell/tissue injury and cytoprotection/organoprotection can be applied to the prevention and treatment of tissue damage in the gastrointestinal tract. Moreover, the publication includes a special chapter on Andre Robert, who has discovered the phenomenon of gastric cytoprotection.This publication will be of great interest for both basic and clinical researchers in gastroenterology and pharmacology, reviewing the advances made so far and pointing towards future developments.
Author | : Gyula Mózsik |
Publisher | : Springer Science & Business Media |
Total Pages | : 366 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9401153922 |
The scientific main programmes of these series of symposia changed from time to time following the international scientific trends. The main programmes of the First Symposium were: 1. Gastric and intestinal cytoprotection; 2. Hepatoprotection; 3. Pancreatic protection. For the second one: 1. Gastrointestinal mucosal 'cytoprotection'; 2. Liver 'cytoprotection'; 3. Pancreatic 'cytoprotection'; 4. Free radicals and scavangers; 5. Computer approach to cytoprotec tion. For the third one: 1. Basic, central, peripheral and cellular mechanisms of gastrointestinaol cytoprotection; 2. Esophagal protection; 3. Gastric protection; 4. Small intestinal injury and protection; 5. Large bowel injury and protection; 6. Liver injury and protection; 7. Pancreas injury and protection. The main scientific programmes of the Fourth International Symposium on 'Cell Injury and Protection in the Gastrointestinal Tract' are: 1. General mechanisms of gastrointestinal injury and protection; 2. Cell injury and protection in the stomach; 3. Cell injury and protection in the small intestine and in the large bowel; 4. Cell injury and protection in the liver and pancreas; 5. Cell injury and protection of the premalignant status and malignant diseases in the gastrointestinal tract. The presented papers are published in this book. The abstracts of this meeting were published in Digestive Diseases and Sciences, and we record appreciation of the Editor ofthatjoumal for their publication. Some of the papers published here have appeared in Inflammopharmacology 1996;4:331-398.
Author | : Gyula Mozsik |
Publisher | : BoD – Books on Demand |
Total Pages | : 368 |
Release | : 2016-03-09 |
Genre | : Medical |
ISBN | : 9535122517 |
The book on Membrane-bound Atp-dependent Energy Systems and the Gastrointestinal Mucosal Damage and Protection deals with various aspects of peptic ulcer disease, like clinical pharmacology, nutrition, molecular biochemical pharmacology as well as clinical aspects, and especially with the evaluation of certain biochemical mechanisms in human gastric mucosa and in animal gastric tissues obtained from different ulcer models. This book can be useful to physiologists; biochemists; pharmacologists, particularly molecular and biochemical pharmacologists; internists; gastroenterologists; biologists; surgeons and pharmacists.
Author | : Daniel Hollander |
Publisher | : Springer Science & Business Media |
Total Pages | : 373 |
Release | : 2007-07-07 |
Genre | : Medical |
ISBN | : 058532154X |
International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future directions for research. This volume will be of interest to scientists and clinicians working in gastroenterology and gastrointestinal physiology.
Author | : Ronald Ross Watson |
Publisher | : Academic Press |
Total Pages | : 322 |
Release | : 2019-01-10 |
Genre | : Science |
ISBN | : 0128144696 |
Dietary Interventions in Gastrointestinal Diseases: Foods, Nutrients and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the gastrointestinal system. It provides nutritional treatment options for those suffering from gastrointestinal diseases including Crohn's Disease, Inflammatory Bowel Disease, Ulcerative Colitis and Allergies, among others. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus showing that changes in intake can change antioxidant and disease preventing non-nutrients and affect gastrointestinal health and/or disease promotion. This book serves as a valuable resource for biomedical researchers who focus on identifying the causes of gastrointestinal diseases and food scientists targeting health-related product development. - Provides information on agents that affect metabolism and other health-related conditions in the gastrointestinal tract - Explores the impact of composition, including differences based on country of origin and processing techniques to highlight compositional differences and their effect on the gastrointestinal tract - Addresses the most positive results from dietary interventions using bioactive foods to impact gastrointestinal diseases, including reduction of inflammation and improved function of organs
Author | : K. D. Rainsford |
Publisher | : Springer Science & Business Media |
Total Pages | : 465 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9401097755 |