The Fungal Cell Wall

The Fungal Cell Wall
Author: Jean-Paul Latgé
Publisher: Springer Nature
Total Pages: 369
Release: 2020-08-12
Genre: Science
ISBN: 3030499286

This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.

Clinical Mycology

Clinical Mycology
Author: Elias J. Anaissie
Publisher: Elsevier Health Sciences
Total Pages: 702
Release: 2009-01-01
Genre: Medical
ISBN: 1416056807

The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical manifestations with accuracy. Expanded therapy content helps you implement the most appropriate treatment quickly, and a bonus CD-ROM-featuring all of the images from the text-enables you to enhance your electronic presentations. Includes specific recommendations for diagnosing, preventing, and treating fungal infections in various patient populations based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. Covers etiologic agents of disease, fungal infections in special hosts such as pediatric patients and patients with cancer and HIV, infections of specific organ systems, and more, to make you aware of the special considerations involved in certain cases. Features clinically useful and reader-friendly practical tools-including algorithms, slides, graphs, pictorials, photographs, and radiographs-that better illustrate and communicate essential points, promote efficient use in a variety of clinical and academic settings, and facilitate slide making for lectures and presentations. Offers a CD-ROM containing all of the book's images for use in your electronic presentations. Offers more clinically relevant images-more than 300 in full color for the first time-to facilitate diagnosis. Features expanded therapy-related content, including up-to-date treatment strategies and drug selection and dosing guidelines. Includes several new sections in the chapter on fungal infections in cancer patients that reflect the formidable clinical challenges these infections continue to present. Presents the work of additional international contributors who have defined many of the key issues in the field, providing more of a global perspective on the best diagnostic and management approaches. Uses a new, full-color design to enhance readability and ease of access to information.

The Fungal Cell Wall

The Fungal Cell Wall
Author: Fausto Almeida
Publisher: Frontiers Media SA
Total Pages: 167
Release: 2020-11-19
Genre: Science
ISBN: 2889661326

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Lectin in Host Defense Against Microbial Infections

Lectin in Host Defense Against Microbial Infections
Author: Shie-Liang Hsieh
Publisher: Springer Nature
Total Pages: 240
Release: 2020-03-09
Genre: Medical
ISBN: 9811515808

This book systemically presents the latest research on lectins, covering all the major topics in the field, including the heterocomplex of lectins and Toll-like receptors, protective versus pathogenic functions in connection with microbial infections, and novel strategies for enhancing host immunity against infectious diseases caused by viruses, bacteria, and fungi. Lectins are a large group of glycan-binding proteins that recognize diverse glycan and non-glycan structures expressed on prokaryotic and eukaryotic cells, and are vital to cell-cell interactions, the attachment of microbes to host cells, and the recognition and activation of immune responses to exogenous and endogenous danger signals. The composition and structure of microbes are complex and include numerous ‘pathogen-associated molecular patterns’ or ‘damage-associated molecular patterns’. As such, microbes’ interactions with immune cells activate multiple innate immunity receptors and produce distinct inflammatory reactions, which can be protective to contain microbial invasion, or pathogenic to cause tissue damage and shock syndrome in the host. The book shares lessons learned from state-of-the art research in this field, highlights the latest discoveries, and provides insightful discussions on lectin-mediated inflammatory reactions, while also outlining future research directions.

Fungal Extracellular Vesicles

Fungal Extracellular Vesicles
Author: Marcio Rodrigues
Publisher: Springer Nature
Total Pages: 193
Release: 2022-01-01
Genre: Science
ISBN: 3030833917

This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host’s immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species. The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology.

The Fungal Cell Wall

The Fungal Cell Wall
Author: Hector Manuel Mora-Montes
Publisher:
Total Pages: 0
Release: 2013
Genre: Science
ISBN: 9781626182295

The fungal cell wall is a shield that protects the cells against changes in the extracellular environment, and from the high internal pressure generated during cell growth. These protective attributes are associated with cell wall robustness and strength, but at the same time the wall has to be plastic and dynamic to allow cell growth and communication with the external environment. The main components of the cell wall are sugars, proteins and lipids. Sugars are the most abundant components of the wall, and are mostly present as polysaccharides of glucose (alpha- and beta-glucans), N-acetylglucosamine (chitin), and glucosamine (chitosan). Most of the cell wall proteins are glycoproteins modified by a glycolipid and/or oligosaccharides covalently attached to asparagine (N-linked glycosylation) or serine/threonine residues (O-linked glycosylation). These wall proteins play important roles in cell wall integrity and structure, sensing changes in the extracellular environment, and some of them have adhesive properties and hydrolytic activities.

Candida and Candidiasis

Candida and Candidiasis
Author: Richard A. Calderone
Publisher: American Society for Microbiology Press
Total Pages: 1222
Release: 2011-12-07
Genre: Medical
ISBN: 1555815391

The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. • Reviews all aspects of this common fungal pathogen and its impact on human health, from the basic biology of Candida albicans to the clinical management of candidiasis. • Reviews the latest basic and clinical research, focusing on findings in genome variability, host-pathogen interactions, antifungal resistance and drug discovery, and diagnostics to foster better understanding and treatment of candidiasis. • Examines recent discoveries that have shed light on morphogenesis and the cell cycle, including how new findings on host responses may have applications for the diagnosis of blood-borne candidiasis.

Fungal Cell Wall

Fungal Cell Wall
Author: José Ruiz-Herrera
Publisher: CRC Press
Total Pages: 203
Release: 2016-04-19
Genre: Science
ISBN: 1439848386

Fungal Cell Wall: Structure, Synthesis, and Assembly, Second Edition is a compendium of information on the chemical structure, synthesis, and organization of the cell wall of fungi. Reviewing the past 20 years of research in the field, it discusses experimental evidence that demonstrates the role of the cell wall in the growth, development, morphog

Candida Albicans

Candida Albicans
Author: Rajendra Prasad
Publisher: Springer Science & Business Media
Total Pages: 273
Release: 2012-12-06
Genre: Science
ISBN: 3642752535

Candida, which was discovered more than a century ago as a causative organism of oral thrush, is now thought to potentially infect almost every tissue of the human body. Although we still do not have a safe anti-candida drug, the growing pace of progess of research on Candida albicans holds promise that a breakthrough is imminent. Though many monographs and articles on candida and candidoses have appeared in recent years, they mostly cover the clinical aspects. This particular text, however, explains the more basic features of candida including the molecular genetics, molecular biology and immunology of the cell wall, the molecular basis of morphogenesis and the structure and function of the plasma membrane. The role of anti-candida drugs and their mechanism of action are also discussed.