Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1)

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1)
Author: Mohd Fauzi Mh Busra
Publisher: Bentham Science Publishers
Total Pages: 311
Release: 2023-07-25
Genre: Medical
ISBN: 9815123114

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics included in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 1 covers techniques for tissue engineering, wound healing and skin engineering. It also presents reviews on techniques such as acellular synthesis and 3D bioprinting. Materials highlighted in this part include chitosan-based nanoparticles, nanocollagen-based materials and plant based composites. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2)

Functional Bio-based Materials for Regenerative Medicine From Bench to Bedside (Part 2)
Author: Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus
Publisher: Bentham Science Publishers
Total Pages: 309
Release: 2024-02-02
Genre: Medical
ISBN: 9815179349

Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 2 covers advanced materials and techniques used in tissue engineering. Topics focus on advanced composite materials for 3D scaffolds and the repair of tissues in different organs such as the heart, cornea, bone and ligaments. Materials highlighted in this part include polyamide composites, electrospun nanofibers, and different bio-based hydrogels. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Biomaterials in Translational Medicine

Biomaterials in Translational Medicine
Author: Lei Yang
Publisher: Academic Press
Total Pages: 364
Release: 2018-11-30
Genre: Technology & Engineering
ISBN: 012813478X

Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. - Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine - Includes the translational or commercialization status of these new biomaterials - Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine - Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles

Advances in Regenerative Medicine: Role of Nanotechnology, and Engineering Principles
Author: Venkatram Prasad Shastri
Publisher: Springer Science & Business Media
Total Pages: 414
Release: 2010-08-14
Genre: Technology & Engineering
ISBN: 9048187885

This book summarizes the NATO Advanced Research Workshop (ARW) on “Nanoengineered Systems for Regenerative Medicine” that was organized under the auspices of the NATO Security through Science Program. I would like to thank NATO for supporting this workshop via a grant to the co-directors. The objective of ARW was to explore the various facets of regenerative me- cine and to highlight role of the “the nano-length scale” and “nano-scale systems” in defining and controlling cell and tissue environments. The development of novel tissue regenerative strategies require the integration of new insights emerging from studies of cell-matrix interactions, cellular signalling processes, developmental and systems biology, into biomaterials design, via a systems approach. The chapters in the book, written by the leading experts in their respective disciplines, cover a wide spectrum of topics ranging from stem cell biology, developmental biology, ce- matrix interactions, and matrix biology to surface science, materials processing and drug delivery. We hope the contents of the book will provoke the readership into developing regenerative medicine paradigms that combine these facets into cli- cally translatable solutions. This NATO meeting would not have been successful without the timely help of Dr. Ulrike Shastri, Sanjeet Rangarajan and Ms. Sabine Benner, who assisted in the organization and implementation of various elements of this meeting. Thanks are also due Dr. Fausto Pedrazzini and Ms. Alison Trapp at NATO HQ (Brussels, Belgium). The commitment and persistence of Ms.

Regenerative Medicine and Stem Cell Biology

Regenerative Medicine and Stem Cell Biology
Author: Nagwa El-Badri
Publisher: Springer Nature
Total Pages: 374
Release: 2020-11-27
Genre: Medical
ISBN: 3030553590

This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.

3D Printing and Biofabrication

3D Printing and Biofabrication
Author: Aleksandr Ovsianikov
Publisher: Springer
Total Pages: 0
Release: 2018-06-08
Genre: Science
ISBN: 9783319454436

This volume provides an in-depth introduction to 3D printing and biofabrication and covers the recent advances in additive manufacturing for tissue engineering. The book is divided into two parts, the first part on 3D printing discusses conventional approaches in additive manufacturing aimed at fabrication of structures, which are seeded with cells in a subsequent step. The second part on biofabrication presents processes which integrate living cells into the fabrication process.

Bone Tissue Engineering

Bone Tissue Engineering
Author: Jeffrey O. Hollinger
Publisher: CRC Press
Total Pages: 462
Release: 2004-10-14
Genre: Medical
ISBN: 1135501912

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Biomedical Product Development: Bench to Bedside

Biomedical Product Development: Bench to Bedside
Author: Babak Arjmand
Publisher: Springer Nature
Total Pages: 164
Release: 2020-02-05
Genre: Medical
ISBN: 3030356264

This textbook covers all the steps in manufacturing a biomedical product from bench to bedside. It specifically focuses on quality assurance and management and explains the different good practice principles in the various phases of product development as well as how to fulfill them: Good laboratory practice, good manufacturing practice and good clinical practice. It provides readers with the know-how to design biomedical experiments to ensure quality and integrity, to plan and conduct standard preclinical studies and to assure the quality of the final manufactured biomedical products. Importantly, it also addresses ethical concerns and considerations. The book discusses the guidelines and ethical considerations for preclinical and clinical studies, to allow readers to identify safety concerns regarding biomedical products and to improve pre-clinical studies for the development of better products. This textbook is a valuable guide for biomedical students (B.Sc., M.S., and Ph.D. students) in the field of molecular medicine, medical biotechnology, stem cell research and related areas, as well as for professionals such as quality control staff, tissue bankers, policy-makers and health professionals.

Biomaterials and Tissue Engineering in Urology

Biomaterials and Tissue Engineering in Urology
Author: John Denstedt
Publisher: Elsevier
Total Pages: 593
Release: 2009-04-29
Genre: Technology & Engineering
ISBN: 1845696379

Urology is the branch of medicine dealing with disorders or diseases of the male genitor-urinary tract and the female urinary tract. This important book summarises the wealth of recent research on the use of biomaterials and tissue engineering to treat urological disorders.Part one reviews the fundamentals with chapters on such topics as biofilms and encrustation formation. Part two then discusses recent advances in biomaterials and design of urological devices such as metal ureteral stents, self-lubricating catheter materials and penile implants. Chapters in Part three address urological tissue engineering with coverage of themes such as artificial and natural biomaterials, nano-technology and placental stem cells for tissue engineering the regeneration of urological tissue and organs.With its eminent editors and international team of contributors, Biomaterials and tissue engineering in urology is an invaluable resource to researchers of urological biomaterials, devices and regenerative medicine in both industry and academia, as well as an important reference for medical practitioners. - Provides a comprehensive review of biomaterials and tissue engineering in urology - Explores the fundamentals of urology, focusing on biofilms and encrustation and formation - Discusses recent advances in biomaterials and the design of urological devices, catheters and stents

Translating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic
Author: Jeffrey Laurence
Publisher: Academic Press
Total Pages: 356
Release: 2015-11-18
Genre: Technology & Engineering
ISBN: 0128005521

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. - Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic - Covers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field - Contains extensive pedagogical updates aiming to improve the education of translational researchers in this field - Provides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine