From Melanocytes To Melanoma
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Cutaneous Melanoma
| Author | : Charles M. Balch |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2020-01-29 |
| Genre | : Medical |
| ISBN | : 9783030050689 |
Written by the leading melanoma experts from the United States, Australia, and Europe, this new edition incorporates the clinical outcomes of more than 70,000 patients treated at major melanoma centers throughout the world and is the definitive and most authoritative textbook on melanoma used worldwide. Providing the most up-to-date and comprehensive information needed for the clinical management and scientific study of melanoma, Cutaneous Melanoma, 6th edition covers everything from precursors of melanoma to advanced stages of metastatic disease.
Histological Diagnosis of Nevi and Melanoma
| Author | : Guido Massi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 764 |
| Release | : 2013-09-16 |
| Genre | : Medical |
| ISBN | : 3642373119 |
The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.
Pathology of Melanocytic Nevi and Malignant Melanoma
| Author | : Michael Piepkorn |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 432 |
| Release | : 2013-03-19 |
| Genre | : Medical |
| ISBN | : 0387216197 |
Highly acclaimed and considered the leading reference in the field, Pathology of Melanocytic Nevi and Malignant Melanoma has now been fully revised and updated to accomodate rapid advances in the field of melanoma pathology. Drs. Michael Piepkorn and Klaus Busam have now joined Dr. Barnhill, world-renowned expert in dermatology and pathology, to expand the text with new sections on the genetics and cytogenetics of melanoma, sentinal lymph node biopsy, the new AJCC TNM staging system for melanoma, the mechanisms of melanoma metastasis. The successful focus and format of the first edition have been preserved. Each lesion and diagnosis is clearly illustrated, now with more than 340 new, digitally enhanced full-color photomicrographs and over 125 tables. A corresponding precis, or concise description of the clinical features, histopathology, differential diagnosis, and outstanding characteristics of each lesion provides readers with a quick yet comprehensive overview of each topic covered. With the inclusion of recent advances in cancer research and new techniques, the second edition of Pathology of Melanocytic Nevi and Malignant Melanoma is the essential reference for every practicing dermatopathologist, pathologist, dermatologist, and cancer research scientist today.
Nevogenesis
| Author | : Ashfaq A. Marghoob |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 160 |
| Release | : 2012-10-13 |
| Genre | : Medical |
| ISBN | : 3642283977 |
The “Abtropfung” theory that nevi develop through the migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the “Hochsteigerung” theory postulated the reverse pattern of migration. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of these theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.
From Melanocytes to Melanoma
| Author | : Vincent J. Hearing |
| Publisher | : Humana Press |
| Total Pages | : 696 |
| Release | : 2005-12-15 |
| Genre | : Medical |
| ISBN | : 9781588294593 |
Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.
Clinical Atlas of Skin Tumors
| Author | : Can Baykal |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 509 |
| Release | : 2014-04-07 |
| Genre | : Medical |
| ISBN | : 3642409385 |
This superb atlas presents an unrivalled wealth of original high-quality clinical photographs of almost all benign and malignant skin tumors. The diverse subtypes and clinical forms, including different localizations, are depicted and careful attention is paid to evolution and follow-up. While the main focus is on the clinical presentation as reflected in the photographs, diagnostic clues and management considerations are also summarized in a straightforward, readily understandable way. The atlas has been designed so that it will meet clinical needs and allow rapid identification of clues relevant to daily practice. Clinical Atlas of Skin Tumors will be valuable for all dermatologists in training as well as for those who are already established in the profession or in allied specialties such as plastic surgery and oncology.
Skin Cancer and UV Radiation
| Author | : Peter Altmeyer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1476 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642607713 |
UV radiation is recognized as the major risk factor for skin can cer. For the last three decades the incidence and mortality of skin cancer have been increasing steadily in almost all parts of the world. Unfortunately, there have been very few advances in the management and treatment of skin cancer. In comparison to other malignant tumors, skin cancer offers the unique opportuni ty to identify this tumor at an early stage. Thus, there is strong interest in preventing death by early diagnosis and prompt treat ment. The proceedings of the International Congress on Skin Cancer and UV Radiation which was held in Bochum Germany in October 1996, reflect the newest scientific standards in the field of skin cancer. The conference in Bochum was a platform for leading scientists from all over the world to discuss the complexity and diversity of UV radiation in its interaction with the skin. Starting with basic science like physiology, immunology, and molecular biochemistry of the skin as influenced by UV radiati on, the book presents a profound survey into the field of skin can cer by focusing on the latest scientific results in prevention, early detection, treatment, and epidemiology. The congress in Bochum in 1996 was organized to provide a starting point for coordinated European strategies against skin cancer with internationally renown scientists.
Recent Advances in the Biology, Therapy and Management of Melanoma
| Author | : Lester Davids |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 388 |
| Release | : 2013-02-13 |
| Genre | : Medical |
| ISBN | : 9535109766 |
The book Recent Advances in the Biology, Therapy and Management of Melanoma brings up-to-date information regarding a number of aspects which culminate in illuminating potential targets in the fight against melanoma. This book is intended to be a reference book for both the scientific and clinical communities and brings complicated subject matter together in an easy, readable way. Undoubtedly fundamental scientific understanding has to then be translated to the clinic in order for us to make significant strides in eradicating melanoma. It is hoped that scientists, clinicians, students and residents find this book useful in their studies on melanoma and that it not only expands their perspectives and views on the field, but challenges them to forge ahead towards discovering the ultimate cure.
Melanins and Melanosomes
| Author | : Jan Borovansky |
| Publisher | : John Wiley & Sons |
| Total Pages | : 395 |
| Release | : 2011-10-05 |
| Genre | : Science |
| ISBN | : 3527644555 |
The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.
