From Breakthrough To Blockbuster
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| Author | : Donald L. Drakeman |
| Publisher | : Oxford University Press |
| Total Pages | : 241 |
| Release | : 2022 |
| Genre | : Biotechnology industries |
| ISBN | : 0195084004 |
"Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. How could a large collection of small companies, most with fewer than 50 employees, compete in one of the world's most breathtakingly expensive and highly regulated industries? This book shows how biotech companies have met the challenge by creating nearly 40% more of the most important treatments for unmet medical needs. Moreover, they have done so with much lower overall costs. The book focuses on both the companies themselves and the broader biotech ecosystem that supports them. Its portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies shows how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions. Looking to the future, it concludes that biomedical research will continue to be most effective in the hands of a large group of small companies as long as national healthcare policies allow the rest of the ecosystem to continue to thrive"--
| Author | : Donald L. Drakeman |
| Publisher | : Oxford University Press |
| Total Pages | : 241 |
| Release | : 2022-02-14 |
| Genre | : Science |
| ISBN | : 0197626300 |
Financial Times Business Top Title March 2022 How could a large collection of small companies, most with fewer than 50 employees, rise to compete with Big Pharma, one of the world's most breathtakingly expensive and highly regulated industries? Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. Biotech companies have met the challenge by creating nearly 40% more of the most important treatments for previously unmet medical needs. Moreover, they have done so with much lower overall costs. From Breakthrough to Blockbuster: The Business of Biotechnology focuses on both the companies themselves and the broader biotech ecosystem that supports them. It paints a portrait of the crucial roles played by academic research, venture capital, contract research organizations, the capital markets, and pharmaceutical companies, demonstrating how a supportive environment enabled the entrepreneurial biotech industry to create novel medicines with unprecedented efficiency. In doing so, it also offers insights for any industry seeking to innovate in uncertain and ambiguous conditions.
| Author | : Gary P. Pisano |
| Publisher | : Harvard Business Press |
| Total Pages | : 278 |
| Release | : 2006 |
| Genre | : Business & Economics |
| ISBN | : 9781591398400 |
Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.
| Author | : Gordon M. Binder |
| Publisher | : Harvard Business Review Press |
| Total Pages | : 326 |
| Release | : 2008 |
| Genre | : Biography & Autobiography |
| ISBN | : |
Under Gordon Binder's leadership, Amgen became the world's largest and most successful biotech company in the world. This text describes what it really takes to manage risk, financing, creative employees, and intellectual property on the international stage.
| Author | : Craig Shimasaki |
| Publisher | : Academic Press |
| Total Pages | : 489 |
| Release | : 2014-04-08 |
| Genre | : Medical |
| ISBN | : 0124047475 |
As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a 'how-to' for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. - Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars - Case studies are interspersed throughout each chapter to support key concepts and best practices. - Enhanced by use of numerous detailed graphics, tables and flow charts
| Author | : Michaelangelo Matos |
| Publisher | : Hachette Books |
| Total Pages | : 480 |
| Release | : 2020-12-08 |
| Genre | : Music |
| ISBN | : 0306903350 |
A Rolling Stone-Kirkus Best Music Book of 2020 The definitive account of pop music in the mid-eighties, from Prince and Madonna to the underground hip-hop, indie rock, and club scenes Everybody knows the hits of 1984 - pop music's greatest year. From "Thriller" to "Purple Rain," "Hello" to "Against All Odds," "What's Love Got to Do with It" to "Wake Me Up Before You Go-Go," these iconic songs continue to dominate advertising, karaoke nights, and the soundtracks for film classics (Boogie Nights) and TV hits (Stranger Things). But the story of that thrilling, turbulent time, an era when Top 40 radio was both the leading edge of popular culture and a moral battleground, has never been told with the full detail it deserves - until now. Can't Slow Down is the definitive portrait of the exploding world of mid-eighties pop and the time it defined, from Cold War anxiety to the home-computer revolution. Big acts like Michael Jackson (Thriller), Prince (Purple Rain), Madonna (Like a Virgin), Bruce Springsteen (Born in the U.S.A.), and George Michael (Wham!'s Make It Big) rubbed shoulders with the stars of the fermenting scenes of hip-hop, indie rock, and club music. Rigorously researched, mapping the entire terrain of American pop, with crucial side trips to the UK and Jamaica, from the biz to the stars to the upstarts and beyond, Can't Slow Down is a vivid journey to the very moment when pop was remaking itself, and the culture at large - one hit at a time.
| Author | : Vicki KUNKEL |
| Publisher | : Amacom Books |
| Total Pages | : 306 |
| Release | : 2008-11-26 |
| Genre | : Business & Economics |
| ISBN | : 0814410219 |
Discover the hidden secrets of mass appeal...and use them to create unbreakable allegiance for products, people, and ideas!
| Author | : Charles Graeber |
| Publisher | : Hachette+ORM |
| Total Pages | : 314 |
| Release | : 2015-12-01 |
| Genre | : Health & Fitness |
| ISBN | : 145556849X |
Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.
| Author | : Bruce Campbell |
| Publisher | : Macmillan |
| Total Pages | : 372 |
| Release | : 2015-10-01 |
| Genre | : Biography & Autobiography |
| ISBN | : 1250099277 |
If Chins Could Kill: Confessions of a B Movie Actor Here we are together in the digital universe. Somehow, you've clicked yourself to this page. If you came here of your own free will and desire, you and I are going to get along just fine. Life is full of choices. Right now, yours is whether or not to download the autobiography of a mid-grade, kind of hammy actor. Am I supposed to know this guy? you think to yourself. No-and that's exactly the point. You can download a terabyte of books about famous actors and their high-falootin' shenanigans. I don't want to be a spoilsport, but we've all been down that road before. Scroll down to that Judy Garland biography. You know plenty about her already-great voice, troubled life. Scroll down a little further to the Charlton Heston book. Same deal. You know his story too-great voice, troubled toupee. The truth is that though you might not have a clue who I am-unless you watch cable very late at night-there are countless working stiffs like me out there, grinding away every day at the wheel of fortune. If Chins Could Kill: Confessions of a B Movie Actor documents my time in blue-collar Hollywood, where movies are cheap, the hours are long, and the filmmaking process can be very personal. To keep up with the times, I've digitized Chins. It was originally published in hardcover/analog fifteen years ago, which is a vast amount of time in the evolution of books and technology, and it was time to get current. The advance of technology is great for a book like this, which is jammed full of pictures. When it came out originally, the photographs all had to be black and white and moderately sized on the page. Now, any photo that was originally taken in color can strut its stuff. Overall, the resolution of the images is off-the-charts better than the first go-around. This is one "sequel" that I'm happy to be a part of, since we could make so many technical improvements. The process was very similar to restoring an old movie. Since I knew that it was going to be reissued, I also had a look at the story being told and decided to condense, move, or clarify some chapters, all or in part. I also tried to add a hint of historical context, since it has been a decade and a half since Chins first came out. I hope you enjoy it. Regards, Bruce Campbell
| Author | : James O'Keefe |
| Publisher | : Simon and Schuster |
| Total Pages | : 352 |
| Release | : 2013-06-18 |
| Genre | : Language Arts & Disciplines |
| ISBN | : 1476706174 |
In this hard-hitting look at the way media and government conspire to protect the status quo, a controversial ambush journalist shows readers what happens when a young citizen journalist challenges some of America's most powerful and protected organizations.
