Fluorescent Analogs Of Biomolecular Building Blocks
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| Author | : Marcus Wilhelmsson |
| Publisher | : John Wiley & Sons |
| Total Pages | : 474 |
| Release | : 2016-04-04 |
| Genre | : Science |
| ISBN | : 1118175867 |
Fluorescent Analogs of Biomolecular Building Blocks focuses on the design of fluorescent probes for the four major families of macromolecular building blocks. Compiling the expertise of multiple authors, this book moves from introductory chapters to an exploration of the design, synthesis, and implementation of new fluorescent analogues of biomolecular building blocks, including examples of small-molecule fluorophores and sensors that are part of biomolecular assemblies.
| Author | : Marcus Wilhelmsson |
| Publisher | : John Wiley & Sons |
| Total Pages | : 448 |
| Release | : 2016-03-16 |
| Genre | : Science |
| ISBN | : 1119179343 |
Fluorescent Analogs of Biomolecular Building Blocks focuses on the design of fluorescent probes for the four major families of macromolecular building blocks. Compiling the expertise of multiple authors, this book moves from introductory chapters to an exploration of the design, synthesis, and implementation of new fluorescent analogues of biomolecular building blocks, including examples of small-molecule fluorophores and sensors that are part of biomolecular assemblies.
| Author | : Bernard Valeur |
| Publisher | : John Wiley & Sons |
| Total Pages | : 595 |
| Release | : 2013-03-25 |
| Genre | : Science |
| ISBN | : 3527328467 |
This second edition of the well-established bestseller is completely updated and revised with approximately 30 % additional material, including two new chapters on applications, which has seen the most significant developments. The comprehensive overview written at an introductory level covers fundamental aspects, principles of instrumentation and practical applications, while providing many valuable tips. For photochemists and photophysicists, physical chemists, molecular physicists, biophysicists, biochemists and biologists, lecturers and students of chemistry, physics, and biology.
| Author | : Ramon Eritja |
| Publisher | : Walter de Gruyter GmbH & Co KG |
| Total Pages | : 380 |
| Release | : 2021-01-18 |
| Genre | : Science |
| ISBN | : 311063953X |
This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
| Author | : Alexander P. Demchenko |
| Publisher | : Springer Nature |
| Total Pages | : 772 |
| Release | : 2023-02-15 |
| Genre | : Medical |
| ISBN | : 3031190890 |
Fluorescence is the most popular technique in chemical and biological sensing because of its ultimate sensitivity, high temporal and spatial resolution and versatility that enables imaging within the living cells. It develops rapidly in the directions of constructing new molecular recognition units, new fluorescence reporters and in improving sensitivity of response up to detection of single molecules. Its application areas range from control of industrial processes to environment monitoring and clinical diagnostics. This book provides systematic knowledge of basic principles in design of fluorescence sensing and imaging techniques together with critical analysis of recent developments. Being a guide for students and young researchers, it also addresses professionals involved in active basic and applied research. Making a strong link between education, research and product development, this book discusses prospects for future progress.
| Author | : Mario Barbatti |
| Publisher | : Springer |
| Total Pages | : 381 |
| Release | : 2014-12-26 |
| Genre | : Science |
| ISBN | : 3319133713 |
The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students
| Author | : Juan Carlos Stockert |
| Publisher | : Bentham Science Publishers |
| Total Pages | : 751 |
| Release | : 2017-12-15 |
| Genre | : Science |
| ISBN | : 1681085186 |
Fluorescence Microscopy is a precise and widely employed technique in many research and clinical areas nowadays. Fluorescence Microscopy In Life Sciences introduces readers to both the fundamentals and the applications of fluorescence microscopy in the biomedical field as well as biological research. Readers will learn about physical and chemical mechanisms giving rise to the phenomenon of luminescence and fluorescence in a comprehensive way. Also, the different processes that modulate fluorescence efficiency and fluorescence features are explored and explained.
| Author | : Kazuhiko Nakatani |
| Publisher | : Springer |
| Total Pages | : 280 |
| Release | : 2016-04-04 |
| Genre | : Science |
| ISBN | : 3319271113 |
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
| Author | : Meni Wanunu |
| Publisher | : CRC Press |
| Total Pages | : 411 |
| Release | : 2011-12-20 |
| Genre | : Medical |
| ISBN | : 1439839735 |
Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the efficacy and nature of interactions between nucleic acids and their putative ligands. This progress can benefit tremendously from new methods that probe nucleic acid/ligand interactions both rapidly and quantitatively. A variety of novel methods for these studies have emerged in recent years, and Methods for Studying DNA/Drug Interactions highlights new and non-conventional methods for exploring nucleic acid/ligand interactions. Designed to present drug-developing companies with a survey of possible future techniques, the book compares their drawbacks and advantages with respect to commonly used tools. Perhaps more importantly, this book was written to inspire young scientists to continue to advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials.
| Author | : Michael L. Johnson |
| Publisher | : Academic Press |
| Total Pages | : 378 |
| Release | : 2011 |
| Genre | : Carrier proteins |
| ISBN | : 0123860032 |
