Field Flow Fractionation Handbook
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| Author | : Martin E. Schimpf |
| Publisher | : John Wiley & Sons |
| Total Pages | : 618 |
| Release | : 2000-08-02 |
| Genre | : Science |
| ISBN | : 9780471184300 |
Field flow fractionation (FFF) is an emerging separation technique, which has been proven successful in the analysis of pharmaceuticals, biotechnology products, polymers, soils, and foods, among others. In this book, Martin Schimpf joins forces with Karin Caldwell and J. Calvin Giddings, two of the primary developers of this technique, to bring you the first comprehensive, one-stop reference on the technique.
| Author | : S. Kim R. Williams |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 306 |
| Release | : 2011-12-07 |
| Genre | : Science |
| ISBN | : 3709101530 |
This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most commonly used solvent systems. Importantly, the field-flow fractionation (FFF) technique has recently emerged as a prominent complement to size exclusion chromatography for protein pharmaceuticals. Fractionation with FFF is gentle and preserves protein structural integrity better than existing alternatives. In the present text, different chapters are written by experts in their respective field of application, who offer comparisons between the FFF techniques and other methods for characterizing their special focus material. Practical guide-lines for successful implementation, such as choice of operating conditions, are offered in conjunction with each application. In addition to new instrumentation and approaches that address important current topics, readers are provided with an overall sense of prior (but timeless) major developments that may be overlooked in literature searches.
| Author | : Guilaume Greyling |
| Publisher | : Springer |
| Total Pages | : 125 |
| Release | : 2019-02-21 |
| Genre | : Technology & Engineering |
| ISBN | : 3030106500 |
This book introduces the reader to thermal field-flow fractionation and discusses its advantages over the fundamental problems associated with traditional column-based analytical techniques commonly used to characterize polymers and macromolecules. The authors discuss the theoretical background, equipment, experimental procedures as well as the recent advances and applications of thermal field-flow fractionation. Complete with several practical examples and troubleshooting guidelines, the book is written for beginners and experienced separation scientists alike and will enable its readers to optimize their experimental conditions for their specific separation needs and problems.
| Author | : Joseph Banoub |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 360 |
| Release | : 2010-11-05 |
| Genre | : Science |
| ISBN | : 9048198798 |
The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.
| Author | : Stepan Podzimek |
| Publisher | : John Wiley & Sons |
| Total Pages | : 325 |
| Release | : 2011-04-20 |
| Genre | : Technology & Engineering |
| ISBN | : 111810272X |
A comprehensive, practical approach to three powerful methods of polymer analysis and characterization This book serves as a complete compendium of three important methods widely used for the characterization of synthetic and natural polymers—light scattering, size exclusion chromatography (SEC), and asymmetric flow field flow fractionation (A4F). Featuring numerous up-to-date examples of experimental results obtained by light scattering, SEC, and A4F measurements, Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation takes an all-in-one approach to deliver a complete and thorough explanation of the principles, theories, and instrumentation needed to characterize polymers from the viewpoint of their molar mass distribution, size, branching, and aggregation. This comprehensive resource: Is the only book gathering light scattering, size exclusion chromatography, and asymmetric flow field flow fractionation into a single text Systematically compares results of size exclusion chromatography with results of asymmetric flow field flow fractionation, and how these two methods complement each other Provides in-depth guidelines for reproducible and correct determination of molar mass and molecular size of polymers using SEC or A4F coupled with a multi-angle light scattering detector Offers a detailed overview of the methodology, detection, and characterization of polymer branching Light Scattering, Size Exclusion Chromatography and Asymmetric Flow Field Flow Fractionation should be of great interest to all those engaged in the polymer analysis and characterization in industrial and university research, as well as in manufacturing quality control laboratories. Both beginners and experienced can confidently rely on this volume to confirm their own understanding or to help interpret their results.
| Author | : Diane Beauchemin |
| Publisher | : Newnes |
| Total Pages | : 588 |
| Release | : 2020-03-15 |
| Genre | : Science |
| ISBN | : 0444594833 |
Sample Introduction Systems in ICPMS and ICPOES provides an in-depth analysis of sample introduction strategies, including flow injection analysis and less common techniques, such as arc/spark ablation and direct sample insertion. The book critically evaluates what has been accomplished so far, along with what can be done to extend the capabilities of the technique for analyses of any type of sample, such as aqueous, gaseous or solid. The latest progress made in fields, such as FIA, ETV, LC-ICP-MS and CE-ICP-MS is included and critically discussed. The book addresses problems related to the optimization of the system, peak dispersion and calibration and automatization. - Provides contributions from recognized experts that give credibility to each chapter as a reference source - Presents a single source, providing the big picture for ICPMS and ICPOES - Covers theory, methods, selected applications and discrete sampling techniques - Includes access to core data for practical work, comparison of results and decision-making
| Author | : Wim Jiskoot |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 694 |
| Release | : 2005-12-05 |
| Genre | : Medical |
| ISBN | : 9780971176720 |
Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. This book explores the nature of different analytical techniques and the way in which they are related to pharmaceutical proteins. In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time.
| Author | : Jack Cazes |
| Publisher | : CRC Press |
| Total Pages | : 2968 |
| Release | : 2009-10-12 |
| Genre | : Science |
| ISBN | : 1439870675 |
Thoroughly revised and expanded, this third edition offers illustrative tables and figures to clarify technical points in the articles and provides a valuable, reader-friendly reference for all those who employ chromatographic methods for analysis of complex mixtures of substances. An authoritative source of information, this introductory guide to specific chromatographic techniques and theory discusses the relevant science and technology, offering key references for analyzing specific chemicals and applications in industry and focusing on emerging technologies and uses.
| Author | : Kevin J. Wilkinson |
| Publisher | : John Wiley & Sons |
| Total Pages | : 702 |
| Release | : 2007-01-30 |
| Genre | : Science |
| ISBN | : 047002433X |
This text presents the current knowledge of environmental colloids and includes reviews of the current understanding of structure, role and behaviour of environmental colloids and particles, whilst focussing directly on aquatic systems and soils. In addition, there is substantial critical assessment of the techniques employed for the sampling, size fractionation and characterisation of colloids and particles. Chemical, physical and biological processes and interactions involving colloids are described, and particular attention is paid to quantitative approaches that take account of particle heterogeneity and polydispersity. Presents critical reviews of the state-of-the-art knowledge of environmental colloids Critical assessment of techniques employed for the sampling, size fractionation and characterisation of colloids and particles are given Theoretical and experimental aspects of the methods as well as the required developments and possible recommendations are discussed Each chapter gives a brief introduction general enough for the non-specialist Written by a internationally recognized group of contributors
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 445 |
| Release | : 2006-10-06 |
| Genre | : Science |
| ISBN | : 0080522548 |
The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. - Presents detailed protocols - Includes troubleshooting tips - Provides coverage on structural biology, computational methods, and biology
