Fentanyl, Inc.

Fentanyl, Inc.
Author: Ben Westhoff
Publisher: Atlantic Monthly Press
Total Pages: 365
Release: 2019-09-03
Genre: Business & Economics
ISBN: 080214795X

A four-year investigation into the world of synthetic drugs—from black market factories to users & dealers to harm reduction activists—and what it revealed. A deeply human story, Fentanyl, Inc. is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. “A whole new crop of chemicals is radically changing the recreational drug landscape,” writes Ben Westhoff. “These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs” —and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice—and those with arcane acronyms like 25i-NBOMe—were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs’ effects impossible to predict. Westhoff has infiltrated this shadowy world. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Westhoff visits the shady factories in China from which these drugs emanate, providing startling and original reporting on how China’s vast chemical industry operates, and how the Chinese government subsidizes it. Poignantly, he chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the United States and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many. “Timely and agonizing. . . . An impressive work of investigative journalism.” —USA Today “Westhoff explores the many-tentacled world of illicit opioids, from the streets of East St. Louis to Chinese pharmaceutical companies, from music festivals deep in the Michigan woods to sanctioned ‘shooting up rooms’ in Barcelona, in this frank, insightful, and occasionally searing exposé. . . . Westhoff’s well-reported and researched work will likely open eyes, slow knee-jerk responses, and start much needed conversations.” —Publishers Weekly “Our 25 Favorite Books of 2019” —St. Louis Post-Dispatch “Best Books of 2019” —Buzzfeed “Best Nonfiction of 2019” —Kirkus Reviews “50 Best Books of 2019” —Daily Telegraph “Best Nonfiction Books of 2019” —Tyler Cowen “Best Books of 2019” —Yahoo Finance

The Least of Us

The Least of Us
Author: Sam Quinones
Publisher: Bloomsbury Publishing USA
Total Pages: 433
Release: 2021-11-02
Genre: Social Science
ISBN: 1635574374

Apple Best Books of 2021 Longlisted for the Andrew Carnegie Medal * Shortlisted for the Zocalo Book Prize From the New York Times bestselling author of Dreamland, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair. Sam Quinones traveled from Mexico to main streets across the U.S. to create Dreamland, a groundbreaking portrait of the opioid epidemic that awakened the nation. As the nation struggled to put back the pieces, Quinones was among the first to see the dangers that lay ahead: synthetic drugs and a new generation of kingpins whose product could be made in Magic Bullet blenders. In fentanyl, traffickers landed a painkiller a hundred times more powerful than morphine. They laced it into cocaine, meth, and counterfeit pills to cause tens of thousands of deaths-at the same time as Mexican traffickers made methamphetamine cheaper and more potent than ever, creating, Sam argues, swaths of mental illness and a surge in homelessness across the United States. Quinones hit the road to investigate these new threats, discovering how addiction is exacerbated by consumer-product corporations. “In a time when drug traffickers act like corporations and corporations like traffickers,” he writes, “our best defense, perhaps our only defense, lies in bolstering community.” Amid a landscape of despair, Quinones found hope in those embracing the forgotten and ignored, illuminating the striking truth that we are only as strong as our most vulnerable. Weaving analysis of the drug trade into stories of humble communities, The Least of Us delivers an unexpected and awe-inspiring response to the call that shocked the nation in Sam Quinones's award-winning Dreamland.

The Future of Fentanyl and Other Synthetic Opioids

The Future of Fentanyl and Other Synthetic Opioids
Author: Bryce Pardo
Publisher:
Total Pages: 0
Release: 2019
Genre: Medical
ISBN: 9781977403384

Deaths involving synthetic opioids, such as fentanyl, increased from roughly 3,000 in 2013 to more than 30,000 in 2018. This book provides readers with insights intended to improve their understanding of the synthetic opioid problem.

Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 483
Release: 2017-09-28
Genre: Medical
ISBN: 0309459575

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

The Age of Fentanyl

The Age of Fentanyl
Author: Brodie Ramin
Publisher: Dundurn
Total Pages: 261
Release: 2020-03-14
Genre: Medical
ISBN: 1459746724

Ottawa Book Award 2021 — Shortlisted • The Donner Prize 2020 — Shortlisted • Speaker's Book Award 2020 — Shortlisted Is there a way to end North America’s opioid epidemic? “A fascinating, wise, and humane analysis of one of the most pressing health challenges of the 21st century.” — Steven Pinker, author of Enlightenment Now In The Age of Fentanyl, Brodie Ramin tells the story of the opioid crisis, showing us the disease and cure from his perspective as an addiction doctor working on the front lines. We meet his patients, hear from other addiction experts, and learn about the science and medicine of opioid addiction and its treatments. He shows us how addiction can be prevented, how knowledge can reduce stigma, and how epidemics can be beaten. Dr. Ramin brings the hopeful message that just as patients and health care workers rallied together to fight HIV one generation ago, a coalition of patients, advocates, scientists, doctors, and nurses is once again finding solutions and making plans to stem the overdose deaths, block the spread of fentanyl, and end the epidemic.

Painkiller Addict

Painkiller Addict
Author: Cathryn Kemp
Publisher: Sphere
Total Pages: 0
Release: 2013-11-19
Genre: Self-Help
ISBN: 9780749958060

WINNER OF THE BIG RED READ PRIZE FOR NON-FICTION IN 2013. Cathryn Kemp was a successful travel journalist who was struck down by a life-threatening illness, pancreatitis. After four years of operations and mis-diagnoses she left hospital with a repeat prescription for fentanyl, a painkiller 100 times stronger than heroin. Within two years she was taking more than ten times the NHS maximum, all on prescription. Her family struggled to understand; her boyfriend left her, she hit rock bottom. Discovering she had only six months to live if she didn't give up the drugs she sold everything she owned and checked into rehab. In the addiction treatment centre she was told that she was unlikely to recover from 'the highest level of opiate-abuse in the clinic's history'. To everyone's amazement, she proved them wrong. This is an extraordinarily poignant, vivid and honest memoir. Based on the twenty-four diaries that the author kept during this period, we travel with Cathryn through her hospital agony, descend with her into the hell of addiction and cheer her as she pulls herself out and upwards. It is a love story, a horror story, a survival story, and one that shows only too clearly the very real dangers of the over-prescription of painkillers and tranquillisers. There is also a resource section for sufferers and their loved ones.

The Essence of Analgesia and Analgesics

The Essence of Analgesia and Analgesics
Author: Raymond S. Sinatra
Publisher: Cambridge University Press
Total Pages: 551
Release: 2010-10-14
Genre: Medical
ISBN: 1139491989

The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Fentanyl

Fentanyl
Author: Amy Sterling Casil
Publisher: Mason Crest Publishers
Total Pages: 0
Release: 2019
Genre: Drug abuse
ISBN: 9781422243794

Fentanyl was developed as a drug that could relieve severe pain and assist doctors in performing complex surgeries. Due to its potent effects, fentanyl is often sold illegally as an ingredient in counterfeit opioid pills or mixed with heroin or cocaine. Because it is nearly impossible to gauge the strength of illegal fentanyl doses, tens of thousands of Americans have overdosed on the drug in recent years. This book provides information about the effects of fentanyl and how it contributes to the ongoing opioid crisis. Opioids are psychoactive drugs derived from the opium poppy, such as heroin or morphine, or synthetic versions that mimic their effects, such as fentanyl or oxycodone. The series Opioid Education: Devastation and the Grip on Society examines various aspects of opioid use and treatment in the United States and the rest of the world. The purpose of this series is to provide young readers with a greater understanding of the ongoing opioid crisis.

Synthesis of Essential Drugs

Synthesis of Essential Drugs
Author: Ruben Vardanyan
Publisher: Elsevier
Total Pages: 635
Release: 2006-03-10
Genre: Medical
ISBN: 008046212X

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references

American Overdose

American Overdose
Author: Chris McGreal
Publisher: PublicAffairs
Total Pages: 346
Release: 2018-11-13
Genre: Social Science
ISBN: 1541773772

A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.