External Field and Radiation Stimulated Breast Cancer Nanotheranostics

External Field and Radiation Stimulated Breast Cancer Nanotheranostics
Author: Nanasaheb D. Thorat
Publisher: Iop Expanding Physics
Total Pages: 450
Release: 2019-09-26
Genre: Science
ISBN: 9780750324144

Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature and reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. This book is a compilation of research development lead by expert researchers and it establishes a single reference module. It addresses, for the first time, all translational aspects and clinical perspectives of physically stimulated breast-cancer nanotheranostics from a wide-ranging and multidisciplinary perception providing unrivalled and comprehensive knowledge in the field.

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics
Author: Sudip Mukherjee
Publisher: Morgan & Claypool Publishers
Total Pages: 50
Release: 2019-10-29
Genre: Medical
ISBN: 1643277863

In this book, cancer theranostics applications of magnetic iron oxide nanoparticles are overviewed in details. Moreover, their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity have been briefly highlighted. Finally, we have mentioned the current examples of clinical trials of magnetic nanoparticles in cancer theranostics along with their future scopes and challenges.

Physics of Cancer

Physics of Cancer
Author: Claudia Mierke
Publisher: Iph001
Total Pages: 500
Release: 2018-10-24
Genre: Science
ISBN: 9780750317511

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

Nanomedicines for Breast Cancer Theranostics

Nanomedicines for Breast Cancer Theranostics
Author: Nanasaheb D. Thorat
Publisher: Elsevier
Total Pages: 440
Release: 2020-03-08
Genre: Technology & Engineering
ISBN: 0128200170

Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer

The Physical Microbe

The Physical Microbe
Author: Stephen J. Hagen
Publisher: Morgan & Claypool Publishers
Total Pages: 146
Release: 2017-10-01
Genre: Technology & Engineering
ISBN: 1681745305

The new field of physical biology fuses biology and physics. New technologies have allowed researchers to observe the inner workings of the living cell, one cell at a time. With an abundance of new data collected on individual cells, including observations of individual molecules and their interactions, researchers are developing a quantitative, physics-based understanding of life at the molecular level. They are building detailed models of how cells use molecular circuits to gather and process information, signal to each other, manage noise and variability, and adapt to their environment. This book narrows down the scope of physical biology by focusing on the microbial cell. It explores the physical phenomena of noise, feedback, and variability that arise in the cellular information-processing circuits used by bacteria. It looks at the microbe from a physics perspective, to ask how the cell optimizes its function to live within the constraints of physics. It introduces a physical and information based -- as opposed to microbiological -- perspective on communication and signaling between microbes. The book is aimed at non-expert scientists who wish to understand some of the most important emerging themes of physical biology, and to see how they help us to understand the most basic forms of life.

Nano-Pharmacokinetics and Theranostics

Nano-Pharmacokinetics and Theranostics
Author: Nanasaheb D. Thorat
Publisher: Academic Press
Total Pages: 324
Release: 2021-07-28
Genre: Business & Economics
ISBN: 0323859828

Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer

Nanostructured Smart Materials

Nanostructured Smart Materials
Author: V. R. Remya
Publisher: CRC Press
Total Pages: 322
Release: 2021-06-30
Genre: Science
ISBN: 1000291561

This new volume presents various research studies that focus on the development of advanced nanomaterials and their composites and blends for different applications in sensing, electrical, biomedical, coating, industrial applications, etc. This book includes detailed discussions on the synthesis, properties, processing, and potential applications of nanomaterials and their blends and composites. Some chapters also explain the basic theoretical aspects of these nanostructured materials and systems, which help readers to develop a better understanding various application areas, including construction. Nanostructured Smart Materials: Synthesis, Characterization and Potential Applications responds to the need for advanced polymeric materials and nanostructured materials with ultimate performance and enhanced qualities and properties for varied applications. The chapters highlight information and research that will be valuable for development of new smart materials. This book will be a useful reference source for universities, colleges, researchers from R&D groups, scientists, postdoctoral fellows, industrialists, graduate and postgraduate students, and faculty.

Biopolymer-Based Nano Films

Biopolymer-Based Nano Films
Author: Mahendra Rai
Publisher: Elsevier
Total Pages: 442
Release: 2021-02-02
Genre: Technology & Engineering
ISBN: 0128233826

Biopolymer-Based Nano Films: Applications in Food Packaging and Wound Healing covers a variety of biofilms, including active biofilms, nisin-silver nano-films, silk fibroin-based composite films, lignocellulose/cellulose-based biofilms, carboxymethyl cellulose-coated polypropylene, hybrid film-loaded antimicrobials, chitosan hybrid systems, pullulan, and biopolymers films. The applications of these nano-biofilms in different fields, particularly in food packaging, wound healing, and as potential antimicrobials against new, emerging, and multidrug resistant microbes are also discussed. This is an important resource for researchers in the fields of pharmacology, nanotechnology, microbiology, biotechnology, and for clinicians. The possibility of associating nanotechnology with biotechnology helps with the creation of innovative new products and the development of processes at the molecular level. Within this context, nanobiotechnology advances and revolutionizes several scientific fields. In the development of new technologies and products, it is also necessary to develop "platforms" that allow the specific application and delivery of compounds/actives in a controlled, specific and non-toxic way. Covers a variety of biofilms Outlines the fundamental properties and major applications of nanostructured biofilms Associates nanotechnology with biotechnology and how they can help with the creation of innovative new products and the development of processes at the molecular level

A Guided Tour of Light Beams

A Guided Tour of Light Beams
Author: David S Simon
Publisher: Morgan & Claypool Publishers
Total Pages: 105
Release: 2016-12-07
Genre: Science
ISBN: 1681744376

From science fiction death rays to supermarket scanners, lasers have become deeply embedded in our daily lives and our culture. But in recent decades the standard laser beam has evolved into an array of more specialized light beams with a variety of strange and counterintuitive properties. Some of them have the ability to reconstruct themselves after disruption by an obstacle, while others can bend in complicated shapes or rotate like a corkscrew. These unusual optical effects open new and exciting possibilities for science and technology. For example, they make possible microscopic tractor beams that pull objects toward the source of the light, and they allow the trapping and manipulation of individual molecules to construct specially-tailored nanostructures for engineering or medical use. It has even been found that beams of light can produce lines of darkness that can be tied in knots. This book is an introductory survey of these specialized light beams and their scientific applications, at a level suitable for undergraduates with a basic knowledge of optics and quantum mechanics. It provides a unified treatment of the subject, collecting together in textbook form for the first time many topics currently found only in the original research literature.

Superparamagnetic Materials for Cancer Medicine

Superparamagnetic Materials for Cancer Medicine
Author: Nanasaheb Thorat
Publisher: Springer Nature
Total Pages: 274
Release: 2023-10-02
Genre: Technology & Engineering
ISBN: 3031372875

This book delves into the methods of synthesis and functionalization of superparamagnetic materials, offering a deep understanding of their properties and applications. It explores the behavioral study of these materials and provides valuable insights into their diverse applications across various fields. A dedicated section focuses on in vitro and in vivo assessment, toxicology considerations, and post-application aspects. Furthermore, the book summarizes the current development of superparamagnetic materials, including an overview of ongoing clinical trials.