Experimental Pharmacology
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Author | : James E. Barrett |
Publisher | : Springer Nature |
Total Pages | : 457 |
Release | : 2019-12-24 |
Genre | : Medical |
ISBN | : 3030353621 |
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
Author | : Anton Bespalov |
Publisher | : Springer Nature |
Total Pages | : 424 |
Release | : 2020-01-01 |
Genre | : Cardiology |
ISBN | : 3030336565 |
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Author | : Bertil B. Fredholm |
Publisher | : Springer Science & Business Media |
Total Pages | : 566 |
Release | : 2010-09-22 |
Genre | : Medical |
ISBN | : 3642134432 |
In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.
Author | : Binghe Wang |
Publisher | : John Wiley & Sons |
Total Pages | : 740 |
Release | : 2016-04-18 |
Genre | : Science |
ISBN | : 1118833368 |
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery
Author | : Beverley Greenwood-Van Meerveld |
Publisher | : Springer |
Total Pages | : 446 |
Release | : 2017-04-19 |
Genre | : Medical |
ISBN | : 3319563602 |
This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
Author | : Hans H. Maurer |
Publisher | : Springer |
Total Pages | : 563 |
Release | : 2019-02-20 |
Genre | : Medical |
ISBN | : 303010561X |
This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly developing phenomenon.
Author | : Andreas-Holger Maehle |
Publisher | : Rodopi |
Total Pages | : 388 |
Release | : 1999 |
Genre | : Medical |
ISBN | : 9789042007932 |
This book describes the main issues of eighteenth-century pharmacology and therapeutics and provides detailed case studies of three key areas: lithontriptics (remedies against urinary stones), opium, and Peruvian bark (quinine).
Author | : Harald H. H. W. Schmidt |
Publisher | : Springer Nature |
Total Pages | : 425 |
Release | : 2021-02-23 |
Genre | : Medical |
ISBN | : 3030685101 |
Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author | : Hannsjörg W. Seyberth |
Publisher | : Springer Science & Business Media |
Total Pages | : 385 |
Release | : 2011-09-01 |
Genre | : Medical |
ISBN | : 3642201954 |
The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.
Author | : Allison D. Fryer |
Publisher | : Springer Science & Business Media |
Total Pages | : 501 |
Release | : 2012-01-06 |
Genre | : Medical |
ISBN | : 3642232744 |
Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and exploited for both therapeutic and non-therapeutic purposes for hundreds of years before the existence of the receptors themselves was recognized. This volume presents a broad yet detailed review of current knowledge of muscarinic receptors that will be valuable both to long-time muscarinic investigators and to those new to the field. It describes the detailed insights that have been obtained on the structure, function, and cell biology of muscarinic receptors. This volume also describes physiological analyses of muscarinic receptors and their roles in regulating the function of the brain and of a variety of peripheral tissues. This volume shows how the study of muscarinic receptors continues to provide new and surprising insights not just to the cholinergic system but to the broad areas of neurobiology, cell biology, pharmacology, and therapeutics.