Due to its potential transformative nature, empathy has increasingly received attention in business, psychology, neuroscience, education, medicine, social sciences and design, to mention only a few. During the last two decades, discussions about the role of empathy in design and creative research and practice have developed, with empathy perceived as a key instrument in human-centred design and design thinking. This book revisits the powerful concept of empathy in the new post-pandemic era in which ubiquitous digitalisation presents challenges to retaining human-centredness when developing products and services. The book presents a practical four-step approach to the challenges presented concerning how organisations can turn from merely feeling empathy with or for people, to actions of empathy and compassion that can be implemented with and by communities. A wide range of organisations and organisational settings can benefit from the presented case studies and research methods. Through them, the book explores how to discover, share and act with empathy and compassion in the new digitally driven post-pandemic era to innovate across a wide range of organisations, including for-profit and not-for-profit businesses and those in the public and third sectors. This edited volume will appeal to global researchers in the fields of product and service design and digital, social innovation, as well those interested in organisational development. The practical, interdisciplinary nature of the book and innovative four-step approach will also appeal to upper-level students.