Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment
Author: National Research Council
Publisher: National Academies Press
Total Pages: 300
Release: 2007-12-19
Genre: Science
ISBN: 0309112982

The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

TSCA Handbook

TSCA Handbook
Author: McKenna Long & Aldridge, LLP
Publisher: Government Institutes
Total Pages: 462
Release: 2005-11
Genre: Law
ISBN: 0865877335

Prompted by important developments that have occurred since the publication of the third edition eight years ago, the newly updated TSCA Handbook provides anyone who manufactures, processes, distributes, or uses chemicals with a comprehensive look at their requirements under the Toxic Substances Control Act (TSCA). Practical and informative, this ready reference details current regulation under TSCA. It examines the Environmental Protection Agency's program for evaluation and regulating new substances, and it discusses PMN preparations and follow through, inspections and audits, and more. Developments addressed in this edition include the following: changes to the Inventory Update Rule, new voluntary testing initiatives, new enforcement policies and rules, revised PCB regulations regarding contaminated sites, and increased maximum civil penalties.

Regulatory Toxicology, Second Edition

Regulatory Toxicology, Second Edition
Author: Shayne C. Gad
Publisher: CRC Press
Total Pages: 424
Release: 2001-07-19
Genre: Medical
ISBN: 9781420025187

This practical resource provides toxicologists and scientists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology also covers the scientific and historical underpinnings of those regulations. Each chapter provides a grounding in the historical events that led to the development of original legislation and major subsequent changes in legislation. The major administrative divisions for regulatory agencies and their main missions and responsibilities are also detailed, as are the basic filing units or documents the agencies require of individuals to meet goals. This second edition is updated to reflect new developments in the field.

OECD Series on Testing and Assessment Guidance on Grouping of Chemicals, Second Edition

OECD Series on Testing and Assessment Guidance on Grouping of Chemicals, Second Edition
Author: OECD
Publisher: OECD Publishing
Total Pages: 141
Release: 2017-04-13
Genre:
ISBN: 9264274677

This guidance document is part of the OECD effort to provide guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category ...