Enzyme Handbook 12
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Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 1017 |
Release | : 2013-06-29 |
Genre | : Science |
ISBN | : 3642611176 |
Recent progress on enzyme immobilisation, enzyme production, coenzyme re generation and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. As more progress in research and application of enzymes has been made the lack of an up-to-date overview of enzyme molecular properties has become more appar ent. Therefore, we started the development of an enzyme data information sys tem as part of protein-design activities at GBF. The present book "Enzyme Hand book" represents the printed vers ion of this data bank. In future a computer searchable version will be also available. The enzymes in this Handbook are arranged according to the Enzyme Com mission list of enzymes. Some 3000 "different" enzymes will be covered. Fre quently enzymes with very different properties are included under the same EC number. Although we intend to give a representative overview on the char acteristics and variability of each enzyme the Handbook is not a compendium. The reader will have to go to the primary literature for more detailed information. Naturally it is not possible to cover aII the numerous literature references for each enzyme (for special enzymes up to 40000) if the data representation is to be concise as is intended.
Author | : Alan J. Barrett |
Publisher | : Elsevier |
Total Pages | : 1182 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 0080984150 |
Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.
Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 1098 |
Release | : 1997-09-24 |
Genre | : Gardening |
ISBN | : 9783540632306 |
This collection of datasheets was generated from the database "BRENDA"
Author | : Dietmar Schomburg |
Publisher | : |
Total Pages | : 982 |
Release | : 1990 |
Genre | : Electronic books |
ISBN | : 9780387564357 |
Includes nomenclature, reactions and specificity, enzyme structure, isolation / preparation, stability, cross references to structure databanks, and literature references for each enzyme.
Author | : Chi-Huey Wong |
Publisher | : Elsevier |
Total Pages | : 392 |
Release | : 1994-07 |
Genre | : Science |
ISBN | : 9780080359410 |
Covering the recent development in enzymatic organic synthesis, this text focuses on the use of isolated enzymes. It includes a discussion of the characteristics of enzymes as catalysts and different types of chemical transformations.
Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 675 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642589030 |
The objective of the Enzyme Handbook is to provide in concise form data on enzymes sufficiently well characterized. The data sheets are arranged in their EC number sequence, volumes 15 to 17 contain Additional Enzymes and updated data sheets to be inserted in previous volumes by their EC-number. For each enzyme, systematic and common names are given, information on reaction type, substrate and product spectrum, inhibitors, cofactors, kinetic data, pH and temperature range, origin, purification, molecular data and storage conditions are listed. A reference list completes the data sheets. This collection is an indispensable source of information for researchers applying enzymes in analysis, synthe.
Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 304 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642589693 |
Today, as the large international genome sequence projects are gaining a great amount of public attention and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products - the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of this knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist or physician to analyse a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the designer of artificial biocatalysts has to choose the optimum prototype to start with.
Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 1037 |
Release | : 2013-11-11 |
Genre | : Science |
ISBN | : 3642844375 |
Recent progress in enzyme immobilisation, enzyme production, coenzyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. As more progress in research and application of enzymes has been made the more apparent has become the Iack of an up-to-date overview of enzyme molecular properties. The need for such a data bank was also expressed by the EC-task force "Biotechnology and Information". Therefore we started the development of an enzyme data information system as part of protein-design activities at GBF. The present book "Enzyme Handbook" represents the printed version of this data bank. ln future it is also planned to make a com puter searchable version available. The enzymes in the Handbook are arranged according to the 1984 Enzyme Commission Iist of enzymes and later supplements. Same 3000 "different" en zymes are covered. Frequently very different enzymes are included under the same E. C. number. Although we intended to give a representative overview on the molecular variability of each enzyme, the Handbook is not a com pendium. The readerwill have to go to the primary Iiterature for more detailed information. Naturally it is not possible to cover all numerous, up to 40 000, Iiterature references for each enzyme if data representation is to be concise as is intended.
Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 980 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642591760 |
Today, as the large international genome sequence projects are gaining a great amount of public attention and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products - the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of that knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist of physician to analyze a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the designer of artificial biocatalysts has to choose the optimum prototype to start with.
Author | : Dietmar Schomburg |
Publisher | : Springer Science & Business Media |
Total Pages | : 988 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 364259025X |
Today, as the large international genome sequence projects are gaining a great amount of public attention and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products -the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of that knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist of physician to analyze a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the designer of artificial biocatalysts has to choose the optimum prototype to start with.