Drugs for the Treatment of Respiratory Diseases

Drugs for the Treatment of Respiratory Diseases
Author: Domenico Spina
Publisher: Cambridge University Press
Total Pages: 622
Release: 2003-01-30
Genre: Medical
ISBN: 9780521773218

Respiratory diseases affect millions of people each year and represent a major health burden around the world. This timely reference surveys and evaluates the drug treatments available for the main categories of lung diseases including asthma, tuberculosis, chronic obstructive pulmonary disease, lung cancer, and respiratory infections. The recent re-emergence of tuberculosis and the increase in asthma in certain populations underlines the importance of finding effective new treatments for these diseases. This publication, a comprehensive reference, is one of the first to survey current and novel drug treatments for this group of diseases. It is certain to establish itself as an essential source of reference for respiratory physicians, clinicians and clinical pharmacologists.

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems
Author: Kamal Dua
Publisher: Academic Press
Total Pages: 620
Release: 2020-08-04
Genre: Technology & Engineering
ISBN: 0128208880

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. - Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases - Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases - Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Disease Control Priorities in Developing Countries

Disease Control Priorities in Developing Countries
Author: Dean T. Jamison
Publisher: World Bank Publications
Total Pages: 1449
Release: 2006-04-02
Genre: Medical
ISBN: 0821361805

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Disease Control Priorities, Third Edition (Volume 5)

Disease Control Priorities, Third Edition (Volume 5)
Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
Total Pages: 948
Release: 2017-11-17
Genre: Medical
ISBN: 1464805202

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Medical Management of Pulmonary Diseases

Medical Management of Pulmonary Diseases
Author: Theodore Marcy
Publisher: CRC Press
Total Pages: 856
Release: 1999-08-27
Genre: Medical
ISBN: 9780824760021

This handy, accessible single volume presents useful clinical information to expose the pathophysiology underlying major pulmonary diseases, and traces the steps of treatment, from establishing diagnosis to managing therapy. Contains more than 400 summary tables, radiographs, pathology specimens, and other illustrations that encapsulate information and highlight key points! A suggested reading list accompanies each chapter to facilitate further study! Written by over 55 internationally recognized experts who provide personal experiences, observations, and review statements, and recommend action based on their expertise dealing with patients, Medical Management of Pulmonary Diseases assesses new, efficient, cost-effective technologies for asthma and for the delivery of oxygen therapy evaluates new directions in the diagnosis and treatment of cystic fibrosis, lung cancer, occupational lung diseases, and diffuse interstitial lung disease describes the anatomy and physiology of the respiratory tract and includes examples of abnormalities drawn from common respiratory diseases discusses standard therapies for most pulmonary disease patients as well as targeted management for specific cases addresses common diagnostic and treatment dilemmas and suggests helpful algorithms for care spotlights asthma, chronic obstructive pulmonary disease, sleep-disordered breathing, tuberculosis, and other conditions that warrant careful management follows the progression of lung cancer from initial diagnosis through staging, and explores individualized therapy options considers special environments that may contribute to respiratory symptoms details the effect pregnancy and surgery have on pulmonary disease and more! Medical Management of Pulmonary Diseases serves as an excellent user-friendly guide ideal for primary care, internal medicine, and family practice physicians; pulmonologists and pulmonary disease specialists; clinical allergists; immunologists; respiratory therapists; thoracic surgeons; physiologists; and medical school students in these disciplines.

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 200
Release: 2011-08-26
Genre: Medical
ISBN: 0309212197

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Oxford Desk Reference: Critical Care

Oxford Desk Reference: Critical Care
Author: Carl Waldmann
Publisher: Oxford University Press, USA
Total Pages: 629
Release: 2008-11-27
Genre: Medical
ISBN: 0199229589

The Oxford Desk Reference: Critical Care allows easy access to evidence-based materials on commonly encountered critical care problems for quick consultation to ensure the optimum management of a particular condition. A concise reference book, it collates key recommendations and presents them in an easily accessible and uniform way.

ERS Handbook of Respiratory Medicine

ERS Handbook of Respiratory Medicine
Author: Paolo Palange
Publisher: European Respiratory Society
Total Pages: 891
Release: 2019-09-01
Genre: Medical
ISBN: 1849840806

The European Respiratory Society (ERS) Handbook of Respiratory Medicine, now in its third edition, is a concise, compact and easy-to-read guide to each of the key areas in respiratory medicine. Its 20 sections, written by clinicians and researchers at the forefront of the field, explain the structure and function of the respiratory system, its disorders and how to treat them. The Handbook is a must-have for anyone who intends to remain up to date in the field, and to have within arm's reach a reference that covers everything from the basics to the latest developments in respiratory medicine.

SARS, MERS and other Viral Lung Infections

SARS, MERS and other Viral Lung Infections
Author: David S. Hui
Publisher: European Respiratory Society
Total Pages: 148
Release: 2016-06-01
Genre: Medical
ISBN: 1849840709

Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.

Oligonucleotide-Based Drugs and Therapeutics

Oligonucleotide-Based Drugs and Therapeutics
Author: Nicolay Ferrari
Publisher: John Wiley & Sons
Total Pages: 576
Release: 2018-07-31
Genre: Medical
ISBN: 1118537335

A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular area of pharmacology and biotech and pharma research, from the basic science behind antisense oligonucleotides chemistry, toxicology, manufacturing, to safety assessments, the design of therapeutic protocols, to clinical experience. Antisense oligonucleotides are single strands of DNA or RNA that are complementary to a chosen sequence. While the idea of antisense oligonucleotides to target single genes dates back to the 1970's, most advances have taken place in recent years. The increasing number of antisense oligonucleotide programs in clinical development is a testament to the progress and understanding of pharmacologic, pharmacokinetic, and toxicologic properties as well as improvement in the delivery of oligonucleotides. This valuable book reviews the fundamentals of oligonucleotides, with a focus on antisense oligonucleotide drugs, and reports on the latest research underway worldwide. • Helps readers understand antisense molecules and their targets, biochemistry, and toxicity mechanisms, roles in disease, and applications for safety and therapeutics • Examines the principles, practices, and tools for scientists in both pre-clinical and clinical settings and how to apply them to antisense oligonucleotides • Provides guidelines for scientists in drug design and discovery to help improve efficiency, assessment, and the success of drug candidates • Includes interdisciplinary perspectives, from academia, industry, regulatory and from the fields of pharmacology, toxicology, biology, and medicinal chemistry Oligonucleotide-Based Drugs and Therapeutics belongs on the reference shelves of chemists, pharmaceutical scientists, chemical biologists, toxicologists and other scientists working in the pharmaceutical and biotechnology industries. It will also be a valuable resource for regulatory specialists and safety assessment professionals and an important reference for academic researchers and post-graduates interested in therapeutics, antisense therapy, and oligonucleotides.