Successful Drug Discovery

Successful Drug Discovery
Author: János Fischer
Publisher: John Wiley & Sons
Total Pages: 256
Release: 2015-02-03
Genre: Medical
ISBN: 3527678441

The first volume of the book series "Successful Drug Discovery" is focusing on new drug discoveries during the last decade, from established drugs to recently introduced drugs of all kinds: small-molecule-, peptide-, and protein-based drugs. The role of serendipity is analyzed in some very successful drugs where the research targets of the lead molecule and the drug are different. Phenotypic and target-based drug discovery approaches are discussed from the viewpoint of pioneer drugs and analogues. This volume gives an excellent overview of insulin analogues including a discussion of the properties of rapid-acting and long-acting formulations of this important hormone. The major part of the book is devoted to case histories of new drug discoveries described by their key inventors. Eight case histories range across many therapeutic fields. The goal of this book series is to help the participants of the drug research community with a reference book series and to support teaching in medicinal chemistry with case histories and review articles of new drugs.

Industry

Industry
Author: William Robin
Publisher: Oxford University Press
Total Pages: 288
Release: 2021-02-08
Genre: Music
ISBN: 0190068671

Amidst the heated fray of the Culture Wars emerged a scrappy festival in downtown New York City called Bang on a Can. Presenting eclectic, irreverent marathons of experimental music in crumbling venues on the Lower East Side, Bang on a Can sold out concerts for a genre that had been long considered box office poison. Through the 1980s and 1990s, three young, visionary composers--David Lang, Michael Gordon, and Julia Wolfe--nurtured Bang on a Can into a multifaceted organization with a major record deal, a virtuosic in-house ensemble, and a seat at the table at Lincoln Center, and in the process changed the landscape of avant-garde music in the United States. Bang on a Can captured a new public for new music. But they did not do so alone. As the twentieth century came to a close, the world of American composition pivoted away from the insular academy and towards the broader marketplace. In the wake of the unexpected popularity of Steve Reich and Philip Glass, classical presenters looked to contemporary music for relevance and record labels scrambled to reap its potential profits, all while government funding was imperilled by the evangelical right. Other institutions faltered amidst the vagaries of late capitalism, but the renegade Bang on a Can survived--and thrived--in a tumultuous and idealistic moment that made new music what it is today.

Discipline and Discovery Series: Exploring Ephesians

Discipline and Discovery Series: Exploring Ephesians
Author: Jackie Seiferth
Publisher: Xulon Press
Total Pages: 194
Release: 2008-08
Genre:
ISBN: 1606475916

Did you ever know how much detail is in each verse of the Bible? In this study you will find out! You will spend twelve weeks going through the book of Ephesians and finding the hidden treasure you once passed over. As you go through this study, you will read the Word, memorize scripture, and pray each day. These are some of the basic blocks of discipline you need for maturity in your walk of faith. Exploring Ephesians will ignite your the passion for the Word of God. Are you ready to put on your armor and learn God's truth? Jackie Seiferth lives in Dublin, CA with her husband, Joe and daughter, Sahara. She has been a Bible study leader and teacher for 5 years, teaching a wide range of women. She is currently enrolled in Northwestern Theological Seminary to pursue a BA/MA degree in Biblical Studies. Her passion is to study the Word of God and inspire others to become excited about what it says. In her free time she loves to snowboard, read, and go to the zoo with her daughter.

Model Rules of Professional Conduct

Model Rules of Professional Conduct
Author: American Bar Association. House of Delegates
Publisher: American Bar Association
Total Pages: 216
Release: 2007
Genre: Law
ISBN: 9781590318737

The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.

Advances in Nucleic Acid Therapeutics

Advances in Nucleic Acid Therapeutics
Author: Michael J Gait
Publisher: Royal Society of Chemistry
Total Pages: 566
Release: 2019-02-11
Genre: Science
ISBN: 1788012097

The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a comprehensive review of the latest advances in the field, covering the background of the development of nucleic acids for therapeutic purposes to the array of drug development approaches currently being pursued using antisense, RNAi, aptamer, immune modulatory and other synthetic oligonucleotides. Nucleic acid therapeutics is a field that has been continually innovating to meet the challenges of drug discovery and development; bringing contributions together from leaders at the forefront of progress, this book depicts the many approaches currently being pursued in both academia and industry. A go-to volume for medicinal chemists, Advances in Nucleic Acid Therapeutics provides a broad overview of techniques of contemporary interest in drug discovery.

A Discovery of Witches

A Discovery of Witches
Author: Deborah Harkness
Publisher: Penguin
Total Pages: 593
Release: 2011-02-08
Genre: Fiction
ISBN: 1101475692

Book one of the New York Times bestselling All Souls series, from the author of The Black Bird Oracle. “A wonderfully imaginative grown-up fantasy with all the magic of Harry Potter and Twilight” (People). Look for the hit series “A Discovery of Witches,” now streaming on AMC+, Sundance Now, and Shudder! Deborah Harkness’s sparkling debut, A Discovery of Witches, has brought her into the spotlight and galvanized fans around the world. In this tale of passion and obsession, Diana Bishop, a young scholar and a descendant of witches, discovers a long-lost and enchanted alchemical manuscript, Ashmole 782, deep in Oxford's Bodleian Library. Its reappearance summons a fantastical underworld, which she navigates with her leading man, vampire geneticist Matthew Clairmont. Harkness has created a universe to rival those of Anne Rice, Diana Gabaldon, and Elizabeth Kostova, and she adds a scholar's depth to this riveting tale of magic and suspense. The story continues in book two, Shadow of Night, book three, The Book of Life, and the fourth in the series, Time’s Convert.

Pattern Discovery in Bioinformatics

Pattern Discovery in Bioinformatics
Author: Laxmi Parida
Publisher: CRC Press
Total Pages: 512
Release: 2007-07-04
Genre: Computers
ISBN: 1420010735

The computational methods of bioinformatics are being used more and more to process the large volume of current biological data. Promoting an understanding of the underlying biology that produces this data, Pattern Discovery in Bioinformatics: Theory and Algorithms provides the tools to study regularities in biological data. Taking a systema